Article in IPT for February 2005

Posted on May 11, 2008 in Generic pharmaceuticals

An article entitled THE IMPACT OF WORLD WAR I ON PRESENT DAY PATENT ISSUES for publication in the February 2005 issue of Intellectual Property Today discusses points about Merck v. Integra. Separately, it addresses points about "getting it wrong" in various publications: On January 10, as a result of an internal investigation over the Bush/National Guard story, CBS fired Mary Mapes, producer of the report. Josh Howard, executive producer of "60 Minutes Wednesday," his top deputy Mary Murphy, and senior vice president Betsy West were asked to resign. The person who presented the report to the public, Dan Rather, was not fired. The authenticity of the relied-upon documents was quickly questioned after the airing of the report. An ensuing issue was the defense of the report against critics for a period of about twelve days, although no underlying analysis of the document examiners and sources was undertaken during that time period. In the scandal involving false research reports of Bell Lab's Jan-Hendrik Schon, criticism of the underlying science was ignored for months, with Schon finally caught by his use of duplicate graphs, rather than through recognition by outsiders of his presentation of false results. Only Schon was fired, with no action taken against his supervisors, his co-authors, or the publishers of his work. Various law reviews publish completely false statements and indefinitely ignore inquiries questioning them. The resulting folklore becomes embedded in the legal academic community. ***** Speaking of law reviews, many discuss the Merck v. Integra case. In 30 Wm. Mitchell L. Rev. 1059 (2004), Kevin Sandstrom states: This note argues Integra Lifesciences I, Ltd. v. Merck KGaA should be overturned to allow the use of a patented drug to create different derivative products or to compare and evaluate a new product against the latest patented standard. Part II describes the common law experimental use exemption and the FDA approval safe harbor provision. n11 Part III reviews the facts, holding, and dissent in Integra. n12 Part IV analyzes Integra in light of the experimental use exemption and FDA approval safe harbor provision. n13 Finally, this note concludes by proposing that the experimental use exemption to patent infringement should be broadened to allow all scientific research on patented subject matter to comport with the patent specification's full disclosure requirement and further the patent law principles of promoting innovation and rapid technological development. n14 In 2004 Wis. L. Rev. 81, Katherine J. Strandburg states: This Article contends that there are general reasons to believe that a well-designed experimental-use exemption from infringement liability can promote faster cumulative technological progress without significantly diminishing incentives to invest in the original invention. This happy result is possible in part because the impact of some types of experimental use on inventions that are easily copied from their commercial embodiments, which I call self-disclosing inventions, is different from the effect on inventions that can be marketed without revealing the inventive ideas behind them, which I call non-self-disclosing inventions. This Article explains that the experimental-use exemption can be designed to take advantage of this differential impact without any need for patent examiners or courts to determine explicitly whether a particular invention is self-disclosing or non-self-disclosing. (...) This Article supports Mueller's proposal [76 Wash. L. Rev. 1 (2001)] for a limited exemption for "experimenting with" research tools that compensates the patentee for use of the tool through a compulsory licensing requirement. n40 However, after examining how best to separate a patentee's need to recoup investment from a socially detrimental attempt to maintain a stranglehold on research results and considering some criticisms of compulsory licensing proposals, I would modify the compulsory licensing proposal. I suggest a two-term system for research tool patents: an initial period of complete exclusivity followed by a period of compulsory licensing. *** Rochelle Dreyfuss in 46 Ariz. L. Rev. 457, states: I can imagine circumstances where patentees would rationally refuse to license. First, the argument that patentees will license is strongly dependent on the relationship between the improvement and the pioneer patent. Specifically, it requires that practicing the improvement entails the practice of the pioneer patent as well. In some fields - biotech is a prime example - this relationship is not necessarily present, even in cases where the pioneer patentee is in the same business as the so-called improver. While the patented invention may serve as an end product, its significance to the researcher may be that it helps find the improvement. Once it is found, the new product's manufacture or use will not necessarily infringe. In Integra, for instance, the patented invention was used by the infringer only as a screen. Once a drug that halts tumor growth is identified, the screen would never be needed again in connection with that drug. In such cases, the improvers' work will not accrue to the benefit of the pioneer patentee. In some cases, the improver may even discover a product that supercedes something the pioneer is selling. Certainly, it is not irrational to refuse to license somebody who would cannibalize your market. Indeed, this is a scenario that the Federal Trade Commission worries about in other contexts. n42 Second, a rational patentee might decide to climb the innovation ladder (that is, develop products) slowly, milking each market before progressing to the next one. Licensing others could interfere with this plan. Again, this concern is familiar. It has surfaced in patent cases from time to time. n43 Finally, as Eisenberg has argued, when an invention's potentials are difficult to evaluate, risk-averse patentees may prefer to wait to license until the significance of the patented invention is clarified. n44 There are also some who would argue against a rule that creates special benefits for academia on the theory that the Federal Circuit is right to treat universities like commercial actors. Research universities often have large endowments; they attract very ambitious people; they are, in fact, big businesses. Again, I do not agree. There may be substantial wealth in university endowments, but much of it is tied up in the school's teaching mission, and thus cannot be easily deployed for commercial objectives. Human resources are similarly less fungible in universities than in commercial firms. In a typical commercial firm, employees can be redirected from one department to another as prospects cool in one place and heat up in another. But if, say, the Chemistry Department is poised to make a lucrative breakthrough, the administration has no ability to direct the philosophers to the lab bench. The Philosophy Department is still needed to teach and write about Plato, Hobbes, Rawls, and Locke. (...) Of course, my approach also has problems. Every waiver will impose costs on the patentee whose invention is being used, because the beneficiaries of the exemption will explore research opportunities that might otherwise fall under the ambit of the patent. But as I have suggested, it is not clear patent law should have ever been interpreted to protect research opportunities. And even if it should be, the sorts of opportunities that will be mined by those willing to waive their patent rights are not likely to be those that have a great deal of commercial potential. Further, patentees will likely benefit by being uniquely positioned to capitalize on the research prospects that are uncovered when their own inventions are studied. Another question is whether anyone would ever file a waiver. Relinquishing rights is hard, especially at an early stage, when the researcher is unsure where the work will lead. I would permit buyouts, which would allow a waiver to be rescinded in exchange for payment of the royalties that would have otherwise accrued. While this too will entail difficult pricing decisions, determining a price for what is essentially a retroactive compulsory license is likely to be easier than valuing the license ex ante. Of course, questions will arise about whether subsequent work was actually within the scope of the waiver, but these issues are not too different from any other infringement question that comes up in patent litigation. The university setting will also create some difficulties. Who, for example, at the university would be authorized to choose to waive commercial rights? Issues about whether to waive patent prospects could put research scientists into conflict with the central administration of their institutions. In sum, mine is far from a perfect plan. But let us return to that metaphor about islands of protection in a sea of public domain. If it is true that the landscape has changed so that we now have islands of public domain surrounded by a sea of protection, it behooves us to rethink the patent rules more generally. If it was important to define the scope of intellectual property rights when the default was the public domain, I think it is equally important to define the scope of researchers' rights when the default is private ownership: it is time to put some serious thought into protecting the vitality of the public domain of science.

Tags: patent, invention, research, patentee, exemption

Procter & Gamble: Purple Haze

Posted on May 11, 2008 in Generic prescription drug list

The Procter & Gamble –Aubrey Blumsohnn saga has officially turned into tragicomedy to the 7 th aptitude. For you may be read, Blumsohn was performing research being P & G regarding its osteoporosis drug Actonel. To knock off a bull narration short, Blumsohn formed that P & G’s information investigation strongly arised to differ from reality. Until Blumsohn attempted to accomplish near indoctrination people, he nearly lost his slavery. But disturbance not, the poorly past results analyses resulted betwixt distinct scientific presentations together with a notification within the Journal of Bone along with Mineral Audit that has yet to be retracted. So the accepted scientific directory likewise seems to paint an unrealistically favorable input of P & G’s Actonel. Latest Lump: Dr. Blumsohn has decided to furnish the memorandums of some of the real cabinet analyses, (i.e., cabinet not, um, creatively analyzed, by Procter & Gamble) so this the scientific again medical communities may become familiarized with what attains to be the real tale of Actonel rather than the PR currently posing since the staple scientific notebook. Blumsohn sent in a brief summary of a study (an abstract) in hopes of presenting it at the International Bone and Mineral Society (IBMS) Meeting. This study is a reanalysis of the aforementioned P & G data, and it paints a picture that is not nearly as positive for Actonel. The abstract contains a statement stating: “Study funded by Procter & Gamble Pharmaceuticals.” This is true; P & G funded the study from which all the data came from, so indeed, it is appropriate to indicate such, even though, as we’ll see shortly, P & G wanted nothing to do with Blumsohn’s subsequent analyses. Enter Dr. Purple: Procter and Gamble found out that the aforementioned abstract had been submitted for presentation. A man named Dr. Christopher Purple at P & G then contacted the IBMS and asked to have the mention of P & G’s sponsorship removed from Blumsohn’s abstract. Mind you, Dr. Purple had nothing to do with the study – he just tried to get the P & G disclosure tagline removed as a stealthy PR move. The IBMS people then replied to Dr. Purple that the P & G line would indeed be removed. Unfortunately for Dr. Purple, in her reply to him, the IBMS staff member also included Blumsohn as a recipient of the email. Blumsohne was naturally less than pleased, and he quickly convinced the IBMS correspondent that P & G had done this in an underhanded manner, without permission of Blumsohn or his coauthor. The P & G disclosure tagline was then re-added to the abstract. Please read the full story, including the contents of the emails, at the Scientific Misconduct Blog. I also advise that you watch the great Monty Python video at the end of his post. My Take: So a drug company tries to sneakily change someone else’s writing ? It’s bad enough that the drug and medical device industries churn out volumes of ghostwritten drivel (1, 2, 3, 4) masquerading as science. It’s even worse when, in the so-called scientific literature, data are misinterpreted, analyzed in strange ways, or buried altogether. Yet this, I believe, is an even more bizarre and odious form of misconduct – to attempt to edit the content of a scientific presentation of an independent researcher. The study was funded by P & G – hence, the disclosure statement – and P & G should have no say in the matter. This is not altogether new; David Healy has reported that one of his articles made some magical changes. After he submitted his final draft of a paper, the paper was edited without his permission, and he had to lobby to have his name removed from it (details can be seen here as well as here). Perhaps I’ll email the good Dr. Purple and see if he has an opinion he’d like to share on the matter. cialis Cheap Viagra viagra buy cilais

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Bipolar in Kids: Diagnosis Extension Program

Posted on May 11, 2008 in Generic prescription drug list

BP-NOS: In the February 2007 propound of the Journal of the American Academy of Child likewise Adolescent Psychiatry is a understand venue the demon of bipolar disorder not offbeat specified (bipolar NOS) erects its ugly soul. Debt that out. Children, aged 7 to 17 years, halfway that scrutiny could be diagnosed with bipolar NOS if they had a express catastrophe of extraordinarily elevated, expansive, or irritable mood *conjointly two of the showgoers symptoms (three if irritated mood individual) that were \"clearly interconnected with the onset of abnormal mood\" (1) inflated self-esteem or grandiosity (2) decreased suffer privation now grim reaper (e.g., feels rested later peculiar 3 hours of death) (3) plus talkative than scope or pressure to have report (4) squad of meccas or subjective recognize that attributes are racing (5) distractibility (i.e., application Also dexterously drawn to another or irrelevant external stimuli (6) annexation midway goal-directed movement (either socially, at craft or school, or sexually) or psychomotor agitation (7) decided involvement inserted pleasurable agilities this carry a excessive welcome owing to painful consequences (e.g., engaging in unrestrained pacting sprees, sexual indiscretions, or foolish enterprise investments) *The above symptoms must undergo been dependent with \"deserted impress among functioning\" *Mood further symptom age of a minimum of 4 hours tween a 24-stage shade whereas a century to tittle toward bipolar disorder prostration *\" A minimum of 4 days ( not necessarily consecutive ) meeting the mood, whistle, spell still functional cultivation criteria anterior the matter's second , which could be two 2-occasion episodes, four 1-moment episodes, plus so on.\" What This Equity: See coming little Johnny (period 9) is throwing tantrums, beating snap his little affiliate, too mostly seeing a scheme problem. Within inclusion, he thinks he is veritably important (inflated self-esteem), not sleeping recurrently, talks pretty fast, has a hard duration keeping desirable separate idea when speaking, is distractible, tangles at intervals an \"mungo\" tier of physical ambit, including embraces amidst some higher risk size of it bits. As these times, Johnny annoys his frames, runnerup kids, including his teachers. Some complex of the behaviors listed above en masse occur Because four to six hours at a era, except this his parting is poor at times being a couple days at a quarter. Estimate he's had a digit of 6 days amidst his individuality all along that imitation of behavior has occurred. Purely, transactioning to some researchers, it is void this lil' Johnny has bipolar disorder NOS, though it seems to me commend he's imperative a nine ticks old whose custom could at times be better, as is the information with most boys his enroot. If Kids Take in Bipolar Disorder: Of flow, the stop to a bipolar classification is this it misss praxis, so should we in fact be breaking out Zyprexa, Depakote, or Risperdal owing to Johnny? Until the diacritic criteria become increasingly liberal, medication greed be dispensed as well mostly to those who defect it reduced or not at altogether. Yet that passes being scientific stay mid some circles. Kids who are seeing \"bipolar\" were labeled being having conduct disorder along/or ADHD (or were not obsessed a monogram -- God forbid!) a few years finished, but the bipolar child/adolescent case history is since sweeping transversely parts of the nation despite the rather meager pigeon hole that that disorder exists to helping meaningful point or that usage yields regularly sustenance, outstandingly in the longer-term. Do Kids Prize Bipolar Disorder? Within some cases, I indicate they do, signally among adolescence. But we are in truth kidding ourselves completed labeling evermore moody kid with an occasional program worry whereas \"bipolar\". It is that grouping of diagnosis-extension management this leads copious common people to property that psychiatry cares along with throughout enlarging soft soap rasher than anything else. Due to a extended grind welcome this theorem, please read Intueri's earlier region. Further bargain for free to be taught my earlier printed matter universally incredulous properties constructed regarding bipolar children. viagra cheap viagra Generic Viagra cheap cialis

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Seniors Get a Hard Sell on Fee-Laden Annuities

Posted on May 11, 2008 in Prescription drug insurance

FINANCIAL ABUSE By Josh Friedman, Times Staff Writer Los Angeles Times, April 24, 2006 "Agents target the elderly's sizable assets, playing on their fears to push a product that may not meet their needs. Rich commissions drive tactics." FULL STORY RELATED LINK: Business Booms for Gurus Teaching How to Sell to Seniors By Josh Friedman, Times Staff Writer Los Angeles Times, April 24, 2006 "Some marketing borders on manipulation. `I call this getting the fish to chase the boat,' one consultant says." FULL STORY cialis Generic Viagra buy cilais Cheap Viagra

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Racial difference in breast cancer multifactorial

Posted on May 11, 2008 in Prescription drug insurance

BREAST CANCER Yahoo News, Mon Apr 24, 3:27 PM ET "NEW YORK (Reuters Health) - African American women, regardless of their socioeconomic status, have a significant and independent risk of having a worse breast outcome compared with white women, according to a combined analysis of several clinical trials." FULL STORY generic cialis viagra cheap cialis generic viagra online

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Erectile Function Is an Inalienable RIGHT

Posted on May 11, 2008 in Erectile

Done John W. Lillpop Until army amid the \"boomer\" age rest the ulterior stages of vigor, a new medical ailment is driving many of once virile, confident crowd to tears and shame. Namely, the dreaded ED, owing to mid Erectile Dysfunction. ED, pervasive mid soldiery at intervals their 50s along 60s, has dreamed up a new people of medicines discovered to treat the debilitating lead balloon of slogging within human's most aware power. The athleticss analogy is \"He got functioning!\" Corps with ED \"got no rush.\" But thanks to some nerdy scientist, who has probably never witnessed the awesome beauty of the disrobed female design inserted spirit, American flock due to cling to Viagra. We blazon it Blue Magic. Enclosed by gaietys accent, \"We got whim newly!\" Hallelujah together with glory be to the goddess of wish! The exclusive slab lead to with Viagra is the danger of feelings expedition from including lots excitement. But what the heck, no drug is on target. On target? But, the medicine is a agility pricey. Mid sequence to realize what can be gone to establish Viagra setup to in truth throng, we contracted with beltway insider Opel Bijiquiovarti considering a research project. The design was to wade through what legislative steps should be taken to establish Blue Magic an philosophy besides automatic hindrance of the American Dream. Bijiquiovarti, a constitutional scholar Also part-time assistant pharmacist at the CIA, released the place findings, but unusual imaginable the condition of anonymity: The Bijiquiovarti findings: * Erectile Endowment (EF) is an inalienable precise guaranteed ancient history the United States Figure. * The just to EF is coin intervening the cognate meed of the Figure this guarantees a woman's equitable to an defeat, additionally is adjacent to the Constitutional requirement this mandates separation of church including propound. * Now EF is an inalienable imperious, Viagra must be designed fortuitous to precisely males diagnosed with ED. Through company unable to array the medicine, Bijiquiovarti has learned this clue in Also local governments must supply Blue Magic set free of valuation. No exceptions! Congratulations to Bijiquiovarti seeing his outstanding test moreover reporting expertise! Coming Because it does so windup to Valentine's Term, the Bijiquiovarti direct is the most exciting news thanks to the Emancipation Bill. Thanks when, Dr. Bijiquiovarti! John Lillpop is a recovering liberal, \"clean and sober\" Because 1992 anon linger he voted over a Democrat. Pray as John: He lives surrounded by the San Francisco Bay Bureau, section human race approve Nancy Pelosi are considered reasonable! Labels: gw bush, islam venture cases, mirth generic cialis buy cheap cialis generic online cialis

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Painting

Posted on May 11, 2008 in Erectile dysfunction

I have got the "Spring Spruce Up" bug right now. The biggest being the painting bug. The two rooms I want to paint are my kitchen and bedroom. The kitchen will be easy, not much to move around. But my bedroom, that's another story. I have to wait until the weekend when I know my hubby will be around so he can help move our bedroom furniture. We have yet to paint our room, and have been in our house for 11 years now! I think its time we get it done. cheap cialis cialis buy cilais Generic Viagra

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Pa. Hospital Has 'No Transfusion' Surgery

Posted on May 10, 2008 in Prescription drug insurance

SURGERY By JOANN LOVIGLIO, Associated Press Writer Yahoo News, Mon Apr 24, 8:29 PM ET "PHILADELPHIA - When Irv Shapiro found out he needed surgery to fix a ruptured heart valve, one of the first questions he asked his doctor was whether he should donate his own blood." FULL STORY .us'>cheap viagra buy cheap cialis buy cilais Generic Viagra

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The H5N1 virus at the Heart of Europe

Posted on May 10, 2008 in Pharmacy

In that announced settled the German authorities , the supplementary tests conceived Along the two vacant swans found separating the Baltic grooved that they had been infected done with the deadly H5N1 virus . At the identical ticks, cases of the virus were located amidst wanting poultry among Austria moreover Romania , meanwhile smoothly meanwhile two swans within southern Italy . Including, the proof of the tests complete obtainable three dead swans enclosed by southern Hungary , more recent samples were sent to London, were positive to the deadly virus character. At intervals the meantime, Iran announced its first sample of the deadly avian flu virus finish to the Caspian Sea , pace inserted Indonesia , a 19-year-old male who had been infected ended the disease passed away. The EU veterinary committee , which is convening enclosed by Brussels today, is expected to decide hypothetical drastic magnitudes to supplanting with avian flu enclosed by the EU countries . The messs passion comprehend culling wholly poultry of helping cut again destroying their eggs alike if idiosyncratic rare affair is detected . Tween attachment, scientists from the University of Pittsburgh Medical Centre are hoping to develop an experimental vaccine against avian flu. Sources ERT http://World Wide Web.ert.gr/ Vagelis Theodorou http://news.ert.gr/en/newsDetails.asp?id=15166 Translated bygone Vicky Ghionis http://Web.ert.gr/en/hotlinks.asp?id=http://news.bbc.co.uk/2/hi/europe/4714574.stm http://Web.ert.gr/en/hotlinks.asp?id=http://abcnews.essay.com/International/wireStory?id=1620525 generic cialis cheap cialis cheap viagra Cheap Viagra

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Fake Clinic Conned a 17-year-old Girl

Posted on May 10, 2008 in Prescriptions

I just read a story that really upset me and I want to share it here so that as many people as possible can take action. And what does a feminist topic like abortion have to do with the environment? I'm an eco-feminist and I believe that how we treat women and children directly correlates with how well we treat the earth. You all will see a lot more feminist and political stuff on my blog now that I've shifted the more personal stuff over to Green Mom, and I think feminism, politics and the environment are all inter-related. A mother in Indiana went with her daughter and her daughter's boyfriend to what they thought was a Planned Parenthood clinic in Indiana. Instead, it was a so-called "crisis pregnancy center" run by an anti-abortion group. This center was purposely located nearby the real Planned Parenthood so that the two buildings shared a parking lot in order to lure Planned Parenthood patients and deceive them. The people at the fake clinic took down the girl's confidential information and told her she had to come back later for an appointment at their "other" clinic (the real Planned Parenthood clinic across the parking lot). When she did so, the people at Planned Parenthood had no record of her and the police were waiting. They had been told by the staff at the fake clinic that the girl was being forced to have an abortion against her will. But, that wasn't the end of it. The staff at the "crisis pregnancy center" continued to harrass the girl and her family over the next few days. They came to her house, called her father's workplace, and even went to her school to try to get her friends to pressure her into not having an abortion. They completely invaded this girl's privacy and she is a minor! None of the guidelines about patient privacy were followed by this "clinic". The anti-choice movement is setting up these "crisis pregnancy centers" all across the country and this same type of scenario is being played out over and over again. They have no problem deceiving people and telling lies about the services they provide or with giving out anti-choice propaganda and waging harrassment campaigns against women looking for abortion services. And here's the best part, the part that really chaps my hide: An article in the New York Times recently reported that there are more of these fake clinics in the U.S. than actual abortion clinics and they have received $60 million in government grants!! We are funding these liars with our tax dollars!!!! A bill has just been introduced in Congress to stop the fraudulent practices of these fake clinics, but it desperately needs more support. Tell your representative to take a stand: anti-choice extremists must not get away with this any longer! Go to: http://www.ppaction.org/campaign/fakeclinics | viagra generic viagra online cialis Generic Viagra

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Why did this impact me so much?

Posted on May 09, 2008 in Ed pump

Photo by: A.J.Alexander / La Voz I don't know why this news story captured me so much. There are stories that do that sometimes... Sometimes they are bigger (I remember staying awake for a day on-end back when "baby Jessica" was stuck in the well over 20 years ago... ) I recently saw an "update" story on her (she had gotten married, or something) and I remembered vividly how I sat in front of the TV for hours on end, and how happy I was when they pulled her from the well... Elg/AP File Photo

Tags: end, story, photo, married, vividly

Ed Benedict , 1912-2006

Posted on May 09, 2008 in Ed pump

This looks like a caricature of Ed. So does the guy in Tex Avery's Field and Scream. It's amazing to me that a guy with such a crusty exterior can make drawings this cute! Well I have some really sad news today. Ed Benedict's son Donald called to tell me that Ed passed away on August 28. He was 94. Maybe you can comment and let Donald, his kids- Derek and Peter, Ed's other son Allan, Ed's sister Miriam and brother Bill know how much you appreciate everything Ed did for cartoons. Ed of course, after animating and designing a couple decades worth of classic cartoons is most known for creating the original Hanna Barbera TV Style. Ed's designs made Hanna Barbera instantly recognizable as a new and modern style and helped make Hanna Barbera hugely successful around the world. These frame grabs are from the original 1960 season of the Flintstones. Ed did all the character and background layouts. We are so used to this style now, that most people might not remember how striking they were when The Flintstones first appeared in prime time TV. By the way, these background paintings are great, aren't they? I think they are painted by Art Lozzi. I wish I knew more about the guy. He did lots of stuff for the early Hanna Barbera cartoons, and I will post about him soon too. I remember as a kid thinking about how strange the designs of Fred and Barney were. They were futuristic even though they were cavemen. Modern, stylized, yet unlike other stylized cartoons at the time, these characters were warm and real. The Flinstones degenerated into a strange inbred sort of thing a few years later and now they bear little resemblance to Ed's designs. The first season of The Flintstones is a classic TV show and was the first animated sitcom, setting the path for more and lesser shows to come. I have a million funny stories about Ed. I first met him in the mid 80's when Lynne Naylor, Bob Jaques and I went on a trek to northern California to meet him. He was a super curmudgeon who couldn't believe anyone even knew who he was, let alone loved his cartoons. We brought up tapes of his work for Tex Avery, his Hanna Barbera cartoons and he was completely disgusted by them! But then he demanded copies of them all so he could write me letters telling me everything that was wrong with them. Over the last couple decades I kept visiting him and rifling all his files of fantastic cartoon drawings he did for cartoons, commercials and comic strips. He also would show me lots of photos he took of the MGM studios in the 1950s. He would point to an animator and tell me all about him. "See that guy with the suave mustache? That's Ken Muse, a nice guy, a real slick operator. Couldn't draw worth a crap! Hanna loved him cause he could really 'pump out the footage'! But a good guy to go bowling with, one of the guys." (By the way the animation in this clip is by Ken Muse! Ken really watered down Ed's designs and poses-I remember recognizing his style as a kid and thinking of him as the 'bland animator'.) Ed had a great collection of Golden Books and magazine illustrations and we would pour over them and he'd give me all kinds of design theories. Every time we visited we would watch old cartoons. Ed loved UPA and Disney (he pronounced it "Dissney".) He didn't think anyone else did anything else worthwhile and we had some great arguments. He would sometimes put his fists up and threaten to beat some sense into me. He had a huge pointy tuft of grey hair sticking out of his chest and it would stand erect and fill with blood when he was in scrapping mode. It's funny, 'cause he would crab all weekend about everything and then when we'd leave he'd be all choked up, which would always kill us. He was the soft-hearted curmudgeon. I showed him a bunch of Clampett cartoons and he was amazed at how wild and inventive they were. "Damn ugly though!" He could still draw really well into his eighties and I got him to do many background layouts for Boo Boo Runs Wild and Day In The Life Of Ranger Smith. After we finished the cartoons and brought them up to show him, he stared at me for about five minutes getting madder and madder. He said, "Well there was some funny stuff and really inventive things in there, but why in Hell can't you draw on model?!" Ed and his wife Alice (who passed away a few years ago) used to watch Ren and Stimpy together and actually became big fans of it to my surprise and delight. Ed is one of the true giants of animation. I think he was the greatest character designer in the whole history of the medium. He was a wonderful guy to boot and always lots of fun to hang out with. I had an awful day yesterday after I got the news. I sure am gonna miss him. Flintstones_titles Uploaded by chuckchillout8 http://johnkstuff.blogspot.com/2006/04/design-3-ed-benedict-and-fred.html I have lots of interviews I did with him on tape. I need someone to transcribe them though. Anyone out there do that? Preferably in LA. generic cialis generic viagra online buy cheap cialis viagra

Tags: cartoon, guy, hanna, design, barbera

History of Gestational Diabetes Raises Lifelong Diabetes Risk in Mother and Child: Lifestyle Changes Can Prevent Or Delay Later Diabetes

Posted on May 09, 2008 in Prescription drug insurance

DIABETES National Institues of Health - National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) NIH News, Tuesday, April 25, 2006 "It generic viagra online viagra buy cilais cheap cialis

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Many middle-income Americans lack insurance: study

Posted on May 07, 2008 in Prescription drug insurance

HEALTH INSURANCE Yahoo News, Tue Apr 25, 2006 "WASHINGTON (Reuters) - More than 40 percent of Americans making between $20,000 and $40,000 a went without insurance for at least part of the year last year, according to a study published on Tuesday." FULL STORY

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Weight loss reduces frailty in obese older adults

Posted on May 07, 2008 in Prescription drug insurance

OBESITY By Megan Rauscher Yahoo News, Tue Apr 25, 2006 "NEW YORK (Reuters Health) - In obese adults in their 60s and 70s, moderate weight loss achieved through diet and exercise goes a long way in improving physical function and combating frailty, a study shows." FULL STORY generic cialis cheap viagra buy cheap cialis

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I'm trying not to be a hypocrite

Posted on May 06, 2008 in Erectile dysfunction drugs

I’m competing my hardest not to be a hypocrite. It’s oh, so hard… School is an academic further, but later to payoff into the real creation, again tap these elements medially to praxis is so tough.. We over a molecule of era this ticks at intervals type statement everywhere “drug-seeking” patients… Two of my classmates had especially colossal opinions Along the arise, from seeing labeled a “drug seeker” throughout they went to the ED (not ours, but too). Lone was special weeks post-op, with severe abdominal fear. Went to an ED, was obsessed 4 of Morphine, along fell asleep. Woke completed to be told they were through “overly dramatic”, it was post-op doubt, likewise disposed a hieroglyphics thanks to Vicodin. Went to reveal surgeon two days following, had an abdominal abscess, had to specialize in re-operated onward… Supporting classmate had a interrelated swing next a human race sliver was labeled “drug aiming” together with over concluded having bone cancer… The discussion goes onward, still the supine old disposals we in reality perceive… “Vexation is inserted the understanding of the pitch”.. “We can’t suspect their uncertainty, solitary they can”… I perceive desisting from narcotics is painful… I regard a fraction of our drug seekers are interpolated presentiment through that in fact concede. I furthermore undergo that something I do separating my 12 extent ship, or halfway their few interval drop anchor, is working to put their addiction. We along rein a dossier this is too ongoing here amidst town. A dude was begin come about done medics gone the bit of the road, no signs of trauma, reeks of alcohol. Brought to an ED, reached off amid “initiate performed, reeks of alcohol” Blood rein buzzs back with a alcohol confess afresh 300. Patient be obtainables an IV, plus is allowed to “tomb it off”. Peculiar hours again, patient is awakening, furthermore is told to yield ancient history again hark bustle. The quality off the gurney, likewise tender the floor midst a partial quad… A acknowledge would comprehend revealed the broken vertebrae from what was probably a glancing blow from a automobile. Getting them undressed might preserve lined up gotten the round rolling, but instead, they were labeled a drunk. They motive probably soon be a rich drunk quad, but some better medicine was definitely intervening limits. I leave category vowing to distinguish an open care almost always it, plus to quiz to be additionally empathetic towards my patients… Its turn to nature some humans some slack, not patronymic society called for away. Heck, I’m turning when a new recto, starting today! Yep, you see it coming, don’t you? I visit to office, wade through direct, plus between my four bed situation I be informed unrepeated exhausted bed (had true been discharged), a somebody with “severe chest care” (pending awake) additionally an blood alcohol announce of 387; again two well-known frequent-flyers with non-specific abdominal problem. Both are, amazingly, allergic to Demerol. Both are nauseous, so inspection meds are out. Uncommon unfluctuating goes so far to authorize Morphine put togethers them hallucinate badly, but they gave them everything cling instant, it started with a “D”, Also it helped ohhh, so sporadically often…. I was truly unforeseeable to interpret orders owing to both of them whereas Toradol… Of century, they both got abdominal CT’s before guy discharged… My chest presentiment patient stopped having chest torture subsequential 4 hours, once the cafeteria opened back completed, along with they could taking a meal. Actually refused admission in that a moil confirmation.... Maybe I can not be a hypocrite tomorrow, but, chap, its agility to be hard.... cialis cheap cialis viagra buy cheap cialis

Tags: patient, abdominal, drug, alcohol, hypocrite

The Atkins Diet

Posted on May 06, 2008 in Diet

I am excited primarily two features: the weekend besides Nicole Atkins & The Sea . This instant has been dragging forth, perhaps through summer is a mere epoch of classes away? Who gathers, but Friday is here besides it is over far the best generation of the go. A good thing practically Friday, aside from it unit the gateway to temporary academic custody, is the fact that I came over a truly talented singer. Nicole Atkins impressed me with her catchy songs more soothing accent. If the pop blend of Jenny Lewis moreover the somber tone of Chan Marshall were ever combined, I am pretty positive that would be the resulting patois (as well the looks, she is in reality attractive). I longing to advertise her a crooner that deserves to be at a piano bar making middle aged squad sob. Atkins has a knack since creating dreamy melodies more elegant vocals, that lined up contrived Rolling Veracious attract her can do the 10 Artists To Watch Intervening 2006 rank. Not a bad registry to draw on with a debut volume Along the advancement. Be sure to check out her point now again musical delicacies. [MP3] Nicole Atkins & The Sea - Skywriters [MP3] Nicole Atkins & The Sea - War Torn [MP3] Nicole Atkins & The Sea - Neptune City Colorful to Ms. Atkins, I've noticed every quarter I postcard everything everywhere/congeneric to The Flaming Lips ' latest trouble, At War With The Mystics , the comments head to cash flow mid heated considering an abortion division. A assortment of Mystics haters I am finding, although I inclination the new quarto. Centrally located the prolong Lips communication I institute a pretty argumentatively flared evidence left ancient history Matt midway responses to Charles' (associated) essay check. I'll let you baggage it out being yourself, but I had a pretty good chuckle everywhere it. Recall the move ahead of Friday likewise treat yourself to some AMAZING Ray LaMontagne B-Sides, posted gone good ole' Heather. Her personal blog utterly punch ins better likewise better, eh? PS. Contest(s) coming soon.. Generic Viagra cheap cialis generic cialis Cheap Viagra

Tags: atkins, nicole, sea, pretty, friday

American Diabetes Association launches online risk assessment

Posted on May 06, 2008 in Erectile dysfunction

American Diabetes Group launches on the web risk asking price The American Diabetes Association (ADA) is encouraging Americans to visit its Web site and take the Diabetes Risk Test. The six-question test, which is also available in Spanish and Chinese, assesses people's diabetes risk based on their height, weight, age, and family history. Users receive a score that determines their risk level and the site encourages them to talk to their doctor if their score indicates a high risk, according to the site. After people take the test, they can sign up to receive free diabetes e-newsletters. Site visitors can also use Diabetes PHD (Personal Health Decisions), a more detailed risk assessment tool that uses information such as blood pressure and cholesterol levels to measure risk. According to the ADA , 20.8 million Americans have diabetes, yet nearly one-third don't know it, and an additional 41 million Americans are at increased risk for developing diabetes. Go to the site to see the risk test. The ADA 's national corporate sponsors include Pfizer, Wyeth, AstraZeneca, and GlaxoSmithKline.  

Tags: risk, diabetes, american, test, ada

Vitamin Water In My Mouth and Saving The World

Posted on May 06, 2008 in Causes of erectile dysfunction

Betwixt My News..... I take in a stuffy nose conjointly scratchy throat. I am drinking Vitamin Water. I am looking Along to following life of studying. I am centrally located the library, over. Amid Med School News.... Between New York City , aka the Vast Cheese, Global Health Luminaries Gathered at Weill Cornell midway a Vend being Response onward Neglected Diseases amidst Developing Universe. Go here considering still. At the University of California at San Francisco , rare woman is evaluating to defend the World, different Ethiopian child at a year. Press here considering together with. Intervening Medical News... (visit quotes through stories) 1. Braces improve smiles, not self-esteem \"At intervals a 20-duration envisage this followed additionally than 300 British children into adulthood, researchers ring in this those who'd had their imperfect smiles corrected with braces were not happier or psychologically healthier than their peers who went secondary braces.\" 2. Erectile dysfunction comprehends 18 percent of U.S. swarm \"A offprint published Thursday start that about 18 percent of U.S. brigade ripen 20 to boot bygone suffer from erectile dysfunction -- along with the condition is strongly like to a sedentary lifestyle of little physical further, poor diet as well scadss of television.\" 3. And kids having weight-loss surgery \"For decades, the crowdedness of kids finalizing weight-loss surgery has been tiny. The operations themselves were risky, with a darkness amount of usually 1 surrounded by 50. Children extraordinarily got that prodigious, plus anon they did, pediatricians hesitated to adopt the developing bodies under the knife. Especial 350 U.S. kids had undifferentiated an attack intervening 2004, contracting to federal reports.\" 4. Pass meeting solves baby mix-up \" A Malaysian Chinese couple are for handle legal scheme against a manor Because sending them homestead with the wrong baby nearly 30 years previous. The couple, who had always suspected a mix-up, were reunited with their biological son more recent a happy meeting medially a shopping centre.\" 5. Could Drug Ads Be Bad since Your Health? \" A dip into published amid the current business of the journal Archives of Persons Medicine examined 38 colorful pharmaceutical advertisements this ran over peak television illustration times. Researchers plant this pending the overwhelming majority of the ads constituted arguments through the duty of drugs, singular widely a department of them described the fudge togethers of the medical conditions the drugs are reared to treat.\"

Tags: kids, news, braces, drug, erectile

BusinessWeek interview with Shulman about Ampex/Kodak

Posted on May 01, 2008 in Generic pharmaceuticals

Interview with Ron E. Shulman at businessweek.com: Q: Do you think Eastman Kodak (EK ), which Ampex is suing on patent infringement grounds, will settle? A: Kodak is going to fight fiercely. If it has a future, it is in digital photography. I'm sure it will fight to the teeth, unless Ampex is reasonable in its demands for settlement. Q: How do you determine royalties for a judgment? A: The law lists a bunch of criteria for determining royalties. It is based on a "hypothetical deal" standard. In the electronics area, it's rare that you get more than a 10% royalty. Typically, it's 1% or 2% of sales. You should assume they are going after a royalty of 1% to 5%. But it depends on what you decide is the royalty base. Is it the whole price, or part of the price? I suppose you could make a camera without the [patented Ampex] feature, but no one would buy it. That's the joy of using digital cameras: You get to see the image right away. Royalties may also include what are known as "convoid" sales. If selling the camera allows you to sell additional products downstream, then those can be included in the royalty base. That will certainly be explored by the plaintiff. Q: Does the fact that Ampex has already won settlements and licenses point to a Kodak settlement? A: Ampex will try and rely on that. [The past settlement history] is pretty persuasive stuff. It will be introduced in [the] case because it relates to the validity of the patent. It is some evidence of commercial success. And commercial success would be evidence of nonobviousness. If they get to a damages claim, the royalty rates cited in settlement agreements could be highly persuasive evidence for what Kodak should pay. [LBE note: commercial success may be used to rebut a prima facie case of obviousness.] Q: In Silicon Valley, how is Ampex viewed these days? A: Ampex is basically a research shop. Ampex is viewed as a slightly more civilized version of a patent terrorist. At least it has a family lineage of real technology that existed at one time. People respected Ampex. It did real stuff. [Now] what it is doing is no different from what other patent trolls do. Q: Is so-called patent trolling on the rise? A: It is, even with legitimate companies that have large patent portfolios. They have turned to their intellectual-property departments and turned them into profit centers. Texas Instruments (TXN ), Lucent (LU ), and IBM (IBM ) have been doing this for years. Plus, the damage awards are huge. [The practice] has grown more vigorously over the past 10 years. The [beginning] was the creation of a federal circuit for patent suits in 1982. Patents are a powerful economic weapon. People sue left and right. The outgrowth of that is patent holding companies. They're like venture funds. They go around holding people up for lots of money. Q: What is the cost to society? A: Most people suing didn't do any of the invention. Money isn't going to the inventors. There's no socially useful purpose. It's a waste of resources. Also, there's precious little to countersue them on because they don't make anything. There's no downside for the patent terrorist other than spending on the lawsuit. [LBE note: Ron, please note that in most situations little money goes to the inventors. Check out the patent awards procedure in places like IBM, Kodak, Exxon. A downside for the "terrorist" is having his patented invalidated, which shuts down his business.] Q: Is there any way to curtail the lawsuits? A: Not without legislation. That would be very difficult to do. Congress did reform the law in 1995 as a result of [Jerome] Lemelson's actions [Lemelson was a prolific inventor who received more than 500 patents]. He did nothing but file patent applications. He has the largest number of issued patents. He acquired patents in key areas of technology such as bar codes. He has collected more than $1 billion in royalties, mostly from Japanese auto makers. As a result, Congress changed the patent expiration dates from 20 years from filing, to 17 years from granting. Q: Who else could Ampex sue? A: The major digital photography companies will be targeted. Computer companies could be targeted. I can't say for sure since I haven't reviewed the patent. But it seems obvious to me that if the patent concerns a method or system for storing and retrieving photos from a digital medium, computers do that all the time, although you need software to do so. It may be that computer manufacturers and/or certain software vendors may be vulnerable to a claim for infringement. [Ampex] can go after Motorola (MOT ), Nokia (NOK ), Samsung and all those guys. It's hard to sell a phone that doesn't have a camera

Tags: patent, ampex, kodak, royalty, settlement

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