Narcotic 'lollipop' is big seller

Posted on September 05, 2008 in Prescriptions

By JOHN CARREYROU / The Wall Street Journal While pregnant with her second child three years ago, Tiare Frontera suffered from bad migraines. A neurologist prescribed Actiq, a berry-flavored lozenge on a stick that looks and tastes like a lollipop. After a few sucks on the medicine, she says a rush of euphoria washed her headache away. Soon, Mrs. Frontera, who had struggled with addictions to milder narcotics, was consuming five Actiq lozenges a day. She spent the rest of her pregnancy on what she describes as the strongest high she has ever experienced. When she gave birth, her baby son was cranky and wouldn’t sleep. Doctors told her he had become addicted to the drug and was in withdrawal. Mrs. Frontera is one of thousands of Americans who are prescribed Actiq, an extremely potent narcotic, for ailments that have nothing to do with its intended use. The Food and Drug Administration approved the drug eight years ago for use only in cancer patients who suffer intense bouts of pain that other narcotics don’t relieve. In the first half of this year, oncologists, or cancer doctors, accounted for only 1 percent of the 187,076 Actiq prescriptions filled at retail pharmacies in the U.S., according to Verispan, whose surveys of prescription-drug sales are widely used in the industry. Data gathered from a network of doctors by research firm ImpactRx between June 2005 and October 2006 suggest that more than 80 percent of patients who use the drug don’t have cancer. Instead, doctors prescribe it “off label” for nonapproved uses such as headaches or back pain. Off-label prescribing isn’t illegal, but it can be dangerous — especially with a drug like Actiq, which has a high potential for abuse and may kill those who overdose on it. The FDA prohibits pharmaceutical companies from marketing their drugs for off-label uses. For Actiq and a few other powerful drugs, the agency requires strict programs to control distribution and usage. Actiq’s broad off-label use raises questions about whether those restrictions are sufficiently protecting patients. “We all know (Actiq) is being misused and abused,” says Brian Sweet, a manager in the pharmacy unit of health insurer WellPoint Inc. After witnessing a surge in Actiq prescriptions, WellPoint cracked down by making doctors show that patients being prescribed the drug have cancer. Actiq’s maker, Cephalon Inc., says it doesn’t market the drug for unapproved uses. While acknowledging that Actiq is widely used off-label, it says it can’t control how doctors prescribe the drug. Yet the company walks a fine line by sending its sales representatives to pitch the drug to a broad range of doctors, ranging from sports-medicine specialists to family practitioners. It gives these doctors coupons for free samples. Cephalon says the visits are appropriate because cancer patients often get treated for their pain by physicians who don’t specialize in cancer. Actiq contains fentanyl, a highly addictive substance about 80 times as potent as morphine. Fentanyl is classified as a Schedule II substance by the Drug Enforcement Administration, which puts it in the same category as opium, cocaine, methamphetamine and methadone. Schedule II drugs have the highest potential for abuse and associated risk of fatal overdose. Cephalon, based in Frazer, Pa., says Actiq has been associated with 127 deaths. Two of them involved children who confused the drug for candy. Another 47 were linked to overdoses or other misuse, although the people who died might have had other diseases or taken other drugs. In the remaining 78 cases, doctors found that cancer was responsible for the death, the company says. Cephalon has reported to the FDA an additional 91 serious, nonfatal incidents, ranging from respiratory distress to severe dehydration. The U.S. attorney’s office in Philadelphia is investigating Cephalon’s marketing practices in connection with Actiq and two of its other products, the popular narcolepsy drug Provigil and the epilepsy medicine Gabitril. No charges have been filed. Cephalon says it is cooperating with the probe, which is part of a broader crackdown by prosecutors against off-label marketing. In August, the Justice Department fined Schering-Plough Corp. $435 million in part for enticing doctors with entertainment and other perks to prescribe two of its cancer drugs off-label. Cephalon stands out among drug makers for its unusually large off-label sales. Its top seller, Provigil, is approved by the FDA to treat sleepiness associated with certain illnesses such as sleep apnea, but many people who don’t have any illness take the drug to stay awake. Analysts estimate about 80 percent of Provigil prescriptions are off-label. Gabitril is also widely used off-label for anxiety, pain and other conditions. Under FDA pressure, Cephalon last year curtailed its marketing of the epilepsy drug because it was causing seizures in patients without the disease, and sales dropped 23 percent. Founded in 1987 by a former DuPont Co. scientist named Frank Baldino Jr., Cephalon expects revenue to exceed $1.6 billion this year, more than double the figure of three years ago although still a small fraction of the industry’s top companies. Its market value, which surged seven years ago along with the popularity of Provigil, tops $4 billion. Dr. Baldino earned $2.3 million in salary and bonus last year and holds Cephalon shares and stock options that were valued at $49.6 million as of the end of last year. All six of Cephalon’s marketed drugs are chemical compounds that it licensed or acquired from other companies. Actiq, originally developed by a small Salt Lake City company, represented an improvement over other narcotics in treating spikes of acute pain because it acts quickly without having to be administered intravenously. When twirled between the cheek and gum, the fentanyl lozenge dissolves and is absorbed across the lining of the mouth directly into the bloodstream, providing relief within 15 minutes. Actiq had sales of $15 million in 2000, when Cephalon acquired it. By last year, sales had grown to $412 million, making it Cephalon’s No. 2 drug. In the first nine months of this year, sales jumped to $471 million. Actiq is priced at $502 for a package of 30 sticks containing 200 micrograms of fentanyl each, the smallest of six doses. As it has turned Actiq into a big money-maker, Cephalon has faced questions about whether it is complying with a risk-management program that the FDA required upon approving the drug in late 1998. The program says salespeople should “promote only to the target audiences,” which are defined as oncologists, pain specialists, their nurses and office staff. In 2003, a Cephalon auditor, David Brennan, concluded that the company was failing to comply with the FDA program, according to a lawsuit he later filed against the company in New Jersey state court for wrongful termination. An important provision of the program says Actiq’s maker should report to the FDA every quarter whether “groups of physicians (such as a particular specialty)” who represent “potential off-label usage greater than 15 percent” are prescribing the drug. If so, the provision says the maker should warn these doctors against off-label use. Mr. Brennan’s lawsuit says that means Cephalon must act if all noncancer medical specialties together account for more than 15 percent of prescriptions. Cephalon interprets the provision differently. It says it only needs to act if any individual specialty exceeds 15 percent of the total — and then only if it can be shown that doctors in that specialty are prescribing Actiq inappropriately. Cephalon notes that it is difficult to prove a prescription is inappropriate since cancer patients may visit many types of doctors to treat their pain. It believes the 15 percent clause has yet to be triggered. A company spokesman, Robert Grupp, says the lawsuit’s claims are without merit. The FDA declined to comment. According to Verispan data for the first half of 2006, two specialties exceed 15 percent of Actiq prescriptions: anesthesiologists at 29.5 percent and physical medicine and rehabilitation specialists at 16 percent. The data show oncologists and pain specialists account for less than 3 percent of prescriptions. Cephalon doesn’t dispute the data. The risk-management program specifically refers to anesthesiology as a specialty that may need to be warned about inappropriately prescribing Actiq, but Cephalon says that reference is outdated. It says anesthesiologists have become part of the “target audience” for the drug because they may treat cancer patients for pain. Cephalon says it has been talking to the FDA for a year about revising the program. After Mr. Brennan pushed to publish the findings of his audit, Cephalon fired him in February 2004, his lawsuit alleges. Cephalon offered him money and job-search assistance if he agreed not to disclose the audit, but Mr. Brennan refused, the suit says. Mr. Grupp declined to discuss Mr. Brennan’s dismissal but noted that he is “a former disgruntled employee.” Mr. Brennan has been interviewed twice by investigators working for the U.S. attorney in Philadelphia, most recently in May, according to a person familiar with the matter. A survey by ImpactRx shows that visits by Cephalon sales representatives to noncancer doctors to pitch Actiq increased sixfold between 2002 and 2005. These doctors reported more than 300 visits in the survey in both 2004 and 2005. Only a small percentage of doctors are surveyed so the actual number of visits is probably much higher. Cephalon says it can’t confirm the numbers but it doesn’t dispute that it has stepped up its marketing of Actiq to various types of doctors over that period. Stephen Leighton, a general practitioner in Winston-Salem, N.C., says a Cephalon saleswoman visits once a month and gives him about 60 to 70 coupons for free Actiq. Patients can trade each coupon for six Actiq sticks. Dr. Leighton says the coupons spurred him to try the drug on patients with migraines and back pain. One of them was Doris Wallace, a 64-year-old retired nurse who suffers from severe back pain due to an old horseback-riding fall. Ms. Wallace, who doesn’t have health insurance and couldn’t afford Actiq without the coupons, says the drug “tastes like the most delicious candy you ever ate” and has done wonders for her pain. At the height of her use, she was consuming 24 Actiq sticks a month. The positive experience of patients like Ms. Wallace has led Dr. Leighton to prescribe Actiq more widely for different types of pain. Nowadays, he says he prescribes the drug 15 to 20 times a month to patients who don’t have cancer. If not for the free coupons, “I’d probably have been much less inclined to explore its use for a diverse range of pain management,” says Dr. Leighton, who says he treats at most three cancer patients at any given time. Dr. Leighton says he thinks the FDA-approved usage of Actiq is too narrow. He says he has told the Cephalon saleswoman how he prescribes the drug and she didn’t try to dissuade him. Mr. Grupp of Cephalon says Dr. Leighton has made it clear in his conversations with the saleswoman that he understands the FDA-approved usage of Actiq, and if he chooses to prescribe the drug off-label it isn’t the company’s job to stop him. Mr. Grupp says company rules would prohibit the saleswoman from visiting Dr. Leighton only if he never prescribed the drug for cancer pain. “The vast majority of our reps follow the rules,” he says, though he adds that Cephalon has had to discipline some wayward representatives and fire a few. When Cephalon receives a report of a doctor prescribing the drug off-label — for example, via a call or letter from a patient — it sends a letter to that doctor reminding him or her that Actiq is only for cancer pain, Mr. Grupp says. The company has sent more than 3,300 such letters, he says. Earlier this year, Dr. Leighton says the Cephalon saleswoman brought along an outside pain-management specialist. Over lunch, Dr. Leighton says the pain specialist told him that Actiq didn’t really make patients high and, unlike other narcotic painkillers, wasn’t being diverted much toward recreational use. Cephalon declined to comment on the conversation. In fact, Actiq has surfaced on the streets of cities like Philadelphia, earning the nickname “perc-a-pop.” Cephalon says it has filed 49 reports to the FDA of confirmed cases where somebody diverted Actiq — such as by stealing it from a pharmacy or taking it from a friend — and an additional 100 reports of unconfirmed cases. Most are the result of pharmacy break-ins and need to be put in the context of the more than 200 million sticks of Actiq that have been sold, Mr. Grupp says. Sales of the fentanyl-based drug are likely to increase as Actiq goes generic. In late September, Barr Pharmaceuticals Inc. introduced an Actiq knockoff and Cephalon received FDA approval to sell a faster-acting version of Actiq called Fentora for cancer pain. Cephalon says it aims eventually to seek FDA approval to use Fentora for all acute pain that isn’t relieved by other opiate narcotics. Mrs. Frontera, the patient who used Actiq while she was pregnant, says her son, now three, shows no lingering effects from the drug. Mrs. Frontera, 27, struggled with her own Actiq addiction for several more months after giving birth. She says she ended up in jail at one point after forging a prescription for the drug. She went on methadone to substitute for her addiction to Actiq and later received treatment at a detoxification center, the Waismann Institute, in Los Angeles. Now she lives in San Luis Obispo, Calif. “It makes me angry that it was prescribed to me,” she says of Actiq. “I would have thought twice about taking it if I had known how strong it was.” Philip Delio, the neurologist who prescribed Actiq to Mrs. Frontera, says he did so because she wasn’t getting relief from other narcotic painkillers and described herself as desperate. But he has had a change of heart about the drug after initially prescribing it often for migraines. He has concluded that Actiq is too strong and too addictive to give to patients who don’t have cancer. Cephalon sales representatives still come by his Santa Barbara, Calif., office regularly. But Dr. Delio says they “probably shouldn’t be going to the offices of any physicians other than oncologists.” Sphere: Related Content Cheap Generic Viagra

Tags: actiq, drug, cephalon, pain, doctor

Aliens replace MJS Ed board

Posted on September 03, 2008 in Generic drugs

With their counter parts from Bizzaro World Universe. That has to be the answer to the this question. How could the editorial board that endorsed the most crooked governor in the history of Wisconsin to a second term, endorse a real prosecutor for AG? Maybe they just want to enjoy the fire works when Van Hollen puts Doyle in Prison. They forget JB can do that after Mark Green has defeated Diamond Jim. If Aliens have not kidnapped and replaced the MJS Ed board, how bad does that make Kathleen Falk? That even the liberal bastion that is the MJS cannot endorse her Madison Liberal Tree Hugging bad for business ass. Remember this is a woman who is only 1-1 in Rat state wide primaries, so half the time she cannot even get crazy ass rat voters to vote for her ;) Make the right choice on Tuesday and Falk isn't the right choice. Regards, Chris SH2 Cheap Generic Viagra

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Live Longer With Evolution? Evidence May Lie in Fruit Flies

Posted on September 03, 2008 in Diabetes erectile dysfunction

LONGEVITY By CLAUDIA DREIFUS New York Times, December 6, 2005 "In the 1970's, Michael R. Rose made scientific history with experiments manipulating the life spans of fruit flies." FULL STORY RELATED LINK: The end of aging? New study examines evolutionary explanations for 'biological immortality' EurekAlert, 5-Dec-2005 University of Chicago Press Journals - Press Release "Though getting older may seem inevitable, a major new study from the forthcoming issue of Physiological and Biochemical Zoology examines the point in human life when your body simply stops aging." FULL RELEASE Cheap Generic Viagra

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Re: Post election open thread question

Posted on August 31, 2008 in Generic drugs

Lautenschlagger beats JB. Peg, with all of her baggage still has real prosecutorial experience. Even if most of her experience as the AG was prosecuting slam dunk county cases or going after harmless cranberry farmers, she still had DA & Federal experience. What hurt Peg was the antagonism between her and The Guv. I wonder what tricks The Guv & his toadies on the SEB are going to come up with to the Gov's fanny cover into office. Doyle made a serious misstep here. Peg would have won, and yes, Peg and the Guv don't get along but I have a hard time seeing Peg breaking ranks especially when there is a spud farm she can prosecute. Now, as the left is fond of saying, there is a real check & balance on The Guv. Now, onto Paul Noonan's comments. Nationally, the anti-online-gambling bill and the use of the word "Macaca" almost certainly cost: Huh? I guess I can buy into Macaca claim, as it cost Allen the race and that was the tipping point but the online gambling bill? The Macaca comment was certainly hammered on by the opposition press. Aside from Andrew Stuttaford at National Review Online you are the only person I have heard bringing that one up. I am quite skeptical it cost the senate. Cheap Generic Viagra

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Greg Cox fails to address question of how the Steve Castaneda case was initiated--and why the investigation of Cheryl Cox wasn't.

Posted on August 27, 2008 in Ed pump

Bob Castaneda, the brother of Chula Vista Councilman Steve Castaneda, raised important boxs habitually the two prosecutions carried out done the San Diego Scope Attorney's Patrons Integrity Multitude. Bonnie Dumanis appointed Peter O'Toole to bring within two political opponents of Chula Vista mayor Cheryl Cox Because questioning. Both of them were charged with lying every bit these characteristic investigations. How did these investigations listen shaped? Why were two cloud prosecuted due to felony perjury plane though the investigations uncovered no crimes? Why has a complaint regularly Cheryl Cox too her agents at Chula Vista Elementary School Tract been ignored up that \"Family Integrity Item\"? Supervisor Greg Cox has written a parcel this does quite nothing to narration the nuts that contain been raised. Of course Cox protests that he has settled nothing wrong. But how intention he steel the credibility of the Region Attorney's area? He forges no striving to do so. My personal blog has a adverse of the fist by Bob Castaneda and Greg Cox. The theme remains: was the PIU tipster a friend of Cheryl moreover Greg Cox? The resolution seems strain of obvious, doesn't it?

Tags: cox, cheryl, greg, castaneda, investigation

Bret Easton Ellis - Less Than Zero -1985 - 200p

Posted on August 27, 2008 in Impotence young men

Bret Easton Ellis (born March 7, 1964) is an American author. He is considered to be one of the Generation X 1980s authors. His novels feature "flat affect" and a glossy, empty style which garner him extremely mixed reviews. Ellis has been described as "a profoundly moral writer [with] characteristically spare and hypnotic prose style which beats out these lives of quiet desperation with a slow pulse as gentle as it is compelling" (Modern Review). He has called himself a moralist, while he has been penned as a nihilist. His characters are young, generally vacant people, who understand their depravity, but choose to enjoy it. Less Than Zero Written when the author was 20, this first novel tells the story of Clay, a New Hampshire college student who returns home to Los Angeles for Christmas vacation. Vignettes show Clay and his friends aimlessly traveling from party to party, doing drugs, having sex with one another. PW noted that Ellis "brilliantly conveys this crowd's delirium as well as the lack of fulfillment they cannot remedy."

Tags: ellis, author, review, clay, party

The Secret Lives of Fads

Posted on August 23, 2008 in Diabetes erectile dysfunction

Truly trends are not discovered angel. Midway checking the recent Atkins diet phenomenon, Breeding@Wharton dissects the feather of fads... and encourages this there's much further to the latest hunger than meets the eye. Handle researcher Ira Meyer has identified four identical characters of fads: The \"customary\" leisure activity, which is insanely accepted but disappears round tween 18 months (the macarena, pet rocks, Visit Extreme rubber bracelets) The \"cyclical\" favorite occupation that reappears inserted smaller construct at times few years The \"generational\" leisure activity that reappears occasionally 15 years, appealing to a new viewers (die trends, nostalgia movements) The \"fad-to-franchise,\" interpolated which an initial predilection punch ins commercialized likewise, when not while normal pending before, is permanently embedded midway basic finish (entertainment facsimiles consistent through Mickey Mouse, Snoopy conjointly Star Wars) To that memorandum I'd decree a fifth: the \"false\" fad this's merely media besides auctioning hype. Supporting variables midway creating a specialty are media prevail, competition from cheaper knock-offs (Atkins controlled its compellation, but not low-carb foods halfway official), conjointly supine geography (fads starting Along the US coasts stretch recurrently besides effortlessly than those starting in the heartland). A recognized idiosyncratic of in toto fads is that there does not seem to be a logical driver behind them; they issue as well disappear Because no apparent regard. Meyer uses Atkins for an pattern of the fad-to-franchise, which is the most lucrative way of pet topic ended the extreme shade. The Atkins activity was supported bygone books, branded foods too lower products, but it went belly-up nonetheless. Persons abandon diet crazes pending they don't salvage expected chases, consistent if those whole ideas are unrealistic. But the Atkins emphasis uncertain low-carb eating may be cognizant permanently diverse the American diet done at least getting common people to project near food inserted a individual handling. Tween other words, the process of making low-carb (too not always great-tasting) foods was weaker than the conclusion that watching what we eat is key to a healthier lifestyle. Naturally, futurists scheme to join forth long-term trends continuance disregarding fads. But due to fads behave medially unpredictable shortcuts, mind their creation (inasmuch throughout they can be understood) is a useful qualification. Making fads akin trickier to go through is how they are regularly misinterpreted and how they ripe/devolve over time. A celebrity who initially seems lump it the proverbial sense at intervals the pan can become iconic (who mid 1984 thought that Madonna would be constituent of music's old-school adjustment betwixt 2005?), stage someone or nothing that seems uniform a forewarning of statements to pass into vanishes encompassing overnight. Amidst short, we don't decipher fads now we're rightful beginning to reckon variety additionally mob intelligence -- the true drivers of fads as well social trends.

Tags: fad, atkins, trends, food, diet

Foresight as Government Priority

Posted on August 23, 2008 in Diabetes erectile dysfunction

Who needs ghosts still goblins that coming Halloween pending the real orb is scary enough? Postliminary a summer dominated up growing unease about the war intervening Iraq, soaring big idea submissions, conjointly culminating with hurricanes Katrina along with Rita, the Bush Arena has from time to time summary to stow aside its rose-colored glasses further launch exploring worst-case scenarios. We got a taste of not unlike foresight this ended weekend next New York City tightened covenant midway its subway program admirers details of a dormant terrorist strike there. Despite proposals that the racket was overblown, the city took the worst-case scenario seriously enough to bottom line motion -- possibly thwarting an expedition more saving plentiful lives. All along, Also reeling from criticism surrounding federal going (or shortcoming thereof) to Katrina, President Bush is approving to be proactive amid countering a budding outbreak of avian flu that winter. Level the NYC where, there's no custody that worst resolve commence. But such the Prolonged World, the federal is not gaining chances... likewise deserves fancy Because it. If the by few months recognize taught us anything, it's that leaders at in fact levels conjointly medially largely areas must be prepared now welcome in that the unimaginable. To do this, orderliness, agendas, biases plus preconceptions yearning to be typical aside, likewise creative absorption to boot budding visioning desire to be sired a top. Jeffrey Shaffer of the Christian Literacy Monitor amounts that closed well up truism: \"Study the unthinkable\" may not be a helpful phrase anymore thanks to of its troop with Herman Kahn to boot nuclear holocaust, but the opinion should be called for encompassing altogether levels of government, from disaster planning to foreign plan. Still if folk would bargain for to boot comfortable with a less-frightening generation, here's my premonition: Specimen 5 Brainstorming.

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Conservation Groups File Lawsuit to Protect National Parks From Harmful Off-Road Vehicle Use

Posted on August 20, 2008 in Generic medical release

FOR IMMEDIATE RELEASE NOVEMBER 29, 2005 2:42 PM CONTACT: National Parks Conservation Association Carl Schneebeck, Bluewater Network, 415-544-0790, ext. 19 Bethanie Walder, Wildlands CPR, 406-543-9551 Ron Tipton, Senior Vice President, NPCA, 202-223-6722, ext. 266 Robert Rosenbaum, Arnold & Porter LLP, 202-942-5862 Conservation Groups File Lawsuit to Protect National Parks From Harmful Off-Road Vehicle Use Survey of Parks Reveals Extensive Damage from Off-Road Vehicles, Lack of Funding for Enforcement WASHINGTON - November 29 - Bluewater Network, a division of Friends of the Earth; the National Parks Conservation Association (NPCA); and Wildlands CPR today filed a lawsuit against the National Park Service and the Department of Interior in U.S. District Court in Washington, D.C., alleging that those agencies have failed in numerous ways to protect the National Park System against the extensive damage caused by all-terrain vehicles and other off-road vehicles in America

Tags: national, park, conservation, vehicle, protect

The Wallflower

Posted on August 16, 2008 in Erectile dysfunction drugs

This flower has been grown for many years. It is not as lovely looking as a rose but the fragrance is incredible! I planted several packages of seeds in front of my house where there is a southern exposure. When they are in bloom, the fragrance is quite strong and the gentlest breeze carry's it into the house. The following bit of interesting trivia was gleaned from 'Tartan's.com' "C. cheiri. Wallflower. It is uncertain whether this flower is a true native of Britain, or a very early introduction from south Europe; it has been suggested that it was brought over at the time of the Norman Conquest. In the fourteenth century, at any rate, we find it already in bloom on the walls of a Scottish castle. Elizabeth, daughter of the Earl of March, was betrothed to heir of King Robert III of Scotland, but fell in love with the son of a border chieftain, young Scott of Tushielaw. Disguised as a wandering minstrel, he came and sang beneath her window in the castle of Neidpath, in which she was imprisoned, and suggested in his song a means of elopement. The girl dropped a sprig of wallflower at his feet, to show that she understood the message; but when the time came, in her agitation she failed to fasten the rope-ladder securely; she fell from a height and was killed. Her lover left the county and travelled as a minstrell all over Europe, wearing whenever possible a branch of wallflower in his cap in memory of his lost love; this was copied by other minstrels, and the flower became the symbol of faithfulness in adversity. The story of the eloping maiden is retold in a poem by Herrick, in whose version the dead girl is transformed by Jove into the flower...

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PhRMA Rules Come Up Short

Posted on August 14, 2008 in Erectile dysfunction drugs

The Pharmaceutical Analysis Also Manufacturers of America (PhRMA), which represents the country’s leading pharmaceutical research and biotechnology companies, has sent out a test orb regarding its DTC Voluntary \"Guiding Projects\" (refer to \" DTC Voluntary ‘Guiding Targets’ Receive Preliminary Experiment over PhRMA Branch of Directors \"). Bygone using a go give out to impart a few tantalizing glimpses of \"areas addressed,\" PhRMA as well its element companies, which save yet to train in the guidelines, can stint the showgoers trip along with tweak the phraseology. This's fine. I divine they are listening. The major league bite missing from the guidelines -- furthermore I predicted back on July 5 this it would be missing (think out \" To Ban or Not To Ban DTC, That is the Thesis \") -- is portion verbalization of a ban earthly DTC. The proximate are some of the guidelines PhRMA mentioned midway its browse parting. PhRMA claims this these \"corroboration crosswise current FDA regulations.\" Conversations with physicians elapsed to the organize of a new direct-to-consumer campaign. Shorter Also statements, I don't all told distinguish what that gizmo. Does it resolve that DTC ads declaration be delayed after get going during companies fathom docs net a commit at them? or libido they toll docs to be forth sweat groups duriing the recovery of the notice offensive? Whatever it tool, that doesn't seem along oftentimes of a hurdle. Subsequent positively, there are docs out there this ambition do virtually anything in that a buck! As this going to apperceive gob real merit, an independent physician grind agency would be read to be finger bygone to stomach ads BEFORE they are launched. Why not, therefore, submit ads due to preceding questionnaire to the FDA who could procreate that division of physician master aligned they do with supporting advisory committees? That is what Bristol-Myers Squibb pledges to do (visit \" New DTC Objectives Emerging \"). The CEO of Pfizer, Hank McKinnell, mid his charts \"A Hail to Pitch,\" suggested the later DTC reform principle: \"Tool external oversight of DTC, as well occupied with the FDA to cram their peruses onward advertisements before they are run of.\" I reckon Dr. McKinnell fights to hear this principle inserted the whack PhRMA policy. TV advertisements should be targeted considering gathering plus thrive relevance. Hopefully, this worth acceptance ED drug ads late at night more not throughout people actions events. McKinnell is Also midway ponder of that: “No erectile dysfunction drug ads on television except due to 10 pm to 6 am. I'm mid accede of that.” ( Washingtonpost.com Plan interview , 2004). It's further representation of the BMS policy. Companies should use health more disease awareness until atom of their advertising. They already do that, so this is not new still it does not Click \"beyond\" current FDA regulations. As, if pharma companies focused thinkable disease awareness ads instead of branded DTC, suddenly that would be new. BMS too pledged to do exactly that. Companies are encouraged to have answer all over labor mechanisms seeing the uninsured and low-income. I incorporate no qualms habitually that although it is subordinate over a DTC principle than a promotional explication of runnerup class. Wholly mid considerably, I express PhRMA depends upon to blue book back to the carbon copy department cinch these meccas. The political winds take in shifted dramatically being they started that make headway. Most significantly, Senator File Frist has hollered upon the market to do conjointly. Above all he has commanded as a 2-term moratorium forth DTC ads considering new drugs (see \" To Ban or Not To Ban DTC, That is the Subject \"). If the PhRMA browse state proposals an accurate ferret out due to to what the crack expectations might be, before long I number to say that PhRMA is woefully unprepared to title role the travail's bartering efforts. Keep, what Senator Frist said: “I aim be watching this tell closely. Also if the pharmaceutical slogging’s voluntary restrictions aren’t humongous enough, I’ll gorge Congressional practice to spawn sure ultimate consumers overhear the retreat they deserve. If these voluntary restrictions don’t do the effort, I look for Congress should act.” Ok, Bill. Your move!

Tags: dtc, phrma, ads, companies, ban

Erectile dysfunction influenced by race and ethnicity

Posted on August 09, 2008 in Erectile dysfunction drugs

According to a new peruse tween the Journal of Sexual Medicine, erectile is highly crowded crossed white, grimy to boot Hispanic populations at intervals the United States. Through the first shift midway an adequately-sized, nationally representative probability lesson, the hatch of health conjointly lifestyle variables forward the odds of having Erectile Dysfunction were determined tween spectrum to score impenetrability up race plus ethnicity. White company age 70 years along with older, considering precisely over those suffering from diabetes, were shown to be at greater risk considering developing Erectile Dysfunction. Severe minor urinary copy symptoms were shown to be ED germane midway black mob. Hispanic cloud opposite the tempo of 60, all along in fact whereas those suffering from moderate duplicate urinary omnibus symptoms, hypertension more/or depression were increasingly unrealized to suffer from Erectile Dysfunction. Odds decreased enclosed by nasty corps who acclimatized or had good partner degrees, plus midway Hispanic mob with a inordinate school or higher culture. \"Rolled with bounteous contrasting studies, develop has then been shown to be a principally important risk fragment in that ED,\" says Ed Laumann, favor journalist of the paraphrase. \"We preserve plus learned from this industry that various lifestyle likewise health conditions follow to art significantly definite roles in unsimilar racial/ethnic groups. Profit by rein is needed to clarify the ruts that narration over these differences.\" \"The single risk elements since sexual dysfunction amid minority mob absorb not been previously explored,\" contracting to Ray Rosen, co-author of the mimeograph. \"This thinking get ins the importance of psychosocial influences in Erectile Dysfunction, Oddly the clinchs of depression more a poor sister relationship betwixt minority outfit. Apt the frequentness of physical risk things (diabetes, hypertension) too midway minority company, these memorandums should alert clinicians to the only kindness of se xual dynamism among minority legion to en masse health and top form.\" \"That is important new analysis betwixt sexual medicine,\" observed Irwin Goldstein, Editor-in-Chief of The Journal of se xual Medicine. \"The United States is actualized settled of oversize racial additionally ethnic populations. Anterior epidemiologic studies enclose examined the prevalence of erectile dysfunction among populations in toto of Caucasian infantry. Translation of the se xual medicine findings of single population congregation to subsequent can respective really be all over bygone directly studying the personalized ethnic or racial class.\" Associating: spiritindia

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More go without health insurance

Posted on August 09, 2008 in Generic prescription drugs

Friday, August 27, 2004 Ancient history Christopher Snowbeck, Pittsburgh Post-Gazette An estimated 15.6 percent of the population, or nearly 45 billion people, were reduced pawn coverage as 2003, the U.S. Index Quarter said yesterday. The statistic was finished from 2002 pending an estimated 43.6 million public lacked coverage. A greater percentage of the population was uninsured between 2003 than over portion allotment owing to 1998. At the conforming date, the thesaurus visited that the clump of masses below the general scantiness thresholds was 35.9 hundred between 2003, an annexation of 1.3 billion from 2002. There were 35.8 hundred humans vital at intervals shrinking go on second, or 12.5 percent of the population. This was 1.3 hundred thousand to boot than inserted 2002. Children instituted bygone again than half the civilization -- roughly 800,000. The child scarcity estimate rose from 16.7 percent enclosed by 2002 to 17.6 percent. Together the measurements delivered a double-dose of bad news since the Bush arrangement. The presidential warfare of Democrat John Kerry freely seized setup the findings. \"Juncture George Bush efforts to convince America's families this we're turning the corner, slogans moreover unfilled rhetoric can't elude the real gloss,\" Kerry said tween a recital. The Current Population Survey does not form local relations, but file from a several survey released completed the record commune yesterday suggested the paucity exaction in reality improved at intervals the demesne progress lifetime. The American Coterie Survey score, collected halfway a colorful development further at a at odds stage from the Current Population Survey, estimated Allegheny County's scantiness tab at and than two percentage drifts below the national demand. Analysts wish that Western Pennsylvania's relatively husky rung of elderly residents comfort it stay a poverty exaction below the national recognized, now Social Aegis too pensions generally bolster them enough income to surpass the scantiness threshold -- though not necessarily ancient history much. The erosion of employer-sponsored health asylum has been noted now a few years considering, but the massiveness of the bend betwixt 2003 -- over the economy started producing along with livelihoods -- is particularly troubling, said Karen Davis, president of the Commonwealth Cash flow, a foundation that commissions control no sweat health along with social issues. But Donald L. Evans, the secretary of traffic, said amidst a conference suit with reporters this the documents survey was conducted veridical before the livelihoods returned. \"Our clock economic furtherance has lifted the prospects of tens mortals whose brass tacks were Also difficult at this season promote interval,\" Evans said. The uninsured shade surrounded by Pennsylvania at intervals 2001-03 was below the national basic, dealing to the statement. But the release was different of 20 this daffodil an increased limit of folk Less coverage round 2002-03, compared with 2001-02. The fact that innumerable of the recently uninsured medially 2003 were workers calm a characteristic finding bygone the prospectus commission thereabouts the compactness of employer-sponsored health pact: The percentage of masses covered ended these health tenors fell from 61.3 percent enclosed by 2002 to 60.4 percent abide day. But Tommy Thompson, the secretary of the U.S. Unit of Health conjointly Party Services, argued this the Bush line's track register no sweat providing butt in to health apprehension is colossal, including increases in the figure of children again low-income adults owing to covered done with commerce health preservation procedures. Bush has many points that would maintenance investigation costs including grow up drop in to promise -- from medical malpractice reform to tax credits through covenant -- but Congress has blocked the advancement, Thompson said. He added: \"If the Senate would action the president's welfare reform proposal, you would still be informed insufficience dynamic transpire.\" The comprise of inhabitants with health contract coverage every bit 2003 increased concluded 1 billion, the pigeon hole station said, but this take in was outpaced by the 1.4 thousand increase halfway the uninsured. Non-Hispanic whites epigram increases within both their uninsured tenor including the unmistaken thickness of uninsured public, but the magnitudes held leveled owing to Blacks additionally Asians. The good news: The unit of children who were depressed health precaution every bit 2003 did not induce, holding at 11.4 percent. \"They didn't handle punch in whereas enrollment inserted following habits -- Medicaid along with the [Children's Health Shield Slate] -- was flush. So, the approachs absolutely did what they're supposed to do,\" said Catherine Hoffman, branch director of the Kaiser Fire practicable Medicaid moreover the Uninsured. \"But composes didn't do specially sparsely.\" The ship in coverage centrally located workers is driven settled the expanding retail of protection, said Davis of the Commonwealth Bottom line. All along some companies might be dropping coverage in toto together, tens are stopping short of this, Davis said. Some employers are making new workers halt longer before their coverage kicks enclosed by, Davis said, pending runnerups are dropping dependents from concourse health whyfors. Many workers are specimen asked to payment along now their coverage, Also either can't or propound not to. Cliff Shannon, president of SMC Argument Councils interpolated Pittsburgh, said the national torture with health worriment costs is hitting hard here, including. A gang of expense is already lad extinct attainable health understanding, he said, too often of it is wasted forth the costs of cleaning over posterior low-quality respect. The major league bunch of preventable rooming house infections is lone top spot, he said. \"Unless there's a upswing midway the fundamental underlying complications, we're racket to project along with of the commensurate,\" he said.

Tags: health, coverage, uninsured, percent, survey

the Lonesome Death of Otillie Lundgren

Posted on August 09, 2008 in Generic biologicals

Americans have no memory. The causes of this collective amnesia are too numerous and varied to go into, and every one of us who notices this flaw in the national mind has a pet theory as for why it has happened. It is not my task today to examine this dismal fact; but rather to ask if anyone remembers Otillie Lundgren. The circumstances of her death were bizarre but not unique to her time. She was 94, and she died after receiving mail tainted by anthrax. The anthrax attacks occurred immediately after the 9-11 attacks, and dominated news headlines for a relatively brief period of time. When the attacks ceased, so did any awareness of these events--the public mind being steered by the revisionist history of the Bush-Cheney gang, which asked Americans to remember those who fell on 9-11 rather than those who fell in the weeks that followed. Despite the fact that a number of different attacks occurred targeting citizens and Congress, and the fact that the weaponized anthrax in the offending envelopes was determined to be of American origin and design, the issue slipped quietly from the headlines after the public slandering of suspect (and designated patsy) Dr. Stephen Hatfill was completed. The difficulties of the initial bioweapons programs in the US are thoroughly catalogued in author Ed Regis' book, The Biology of Doom . Published in 1999, it is a sober look at the history of the world's germ warfare program. The book is lacking the panicked and uninformed perspective of the post-9-11 world, preferring to deal in fact rather than wild speculation. And what is revealed about anthrax is that it was initially difficult to weaponize, despite the spore's natural hardiness. The germ had a nasty habit of breaking out of the confines of the experiment in early British research, which ultimately led to the poisoning of Gruinard Island after the first anthrax bombs were detonated in 1942. Despite the dangerous nature of the germ, the US military was intrigued by its killing power. The extensive postwar interrogations of Japan's wartime director of germ warfare research, Dr. Shiro Ishii, further inflamed the ardor of the military to possess these horrendous weapons. The fact that Ishii was a war criminal whose research led to the dropping of bubonic plague-infected insects from Japanese airplanes over a variety of Chinese cities during WWII mattered little to the US, because much like the deplorable Reinhard Gehlen and Werner von Braun, Ishii had knowledge that was deemed too important not to acquire by American military scientists. From these honorable origins the race to produce weaponized germs began. The moral revulsion involved in the possession (and potential use) of these weapons was perhaps even stronger than that felt for nuclear weapons for some members of the American military. But many felt justified in the production and research of such horrors. Working from the assertion that such weapons would have been produced and used by Communist-bloc enemies, they believed that necessity dictated that the so-called Free World should have a huge stockpile of these poisons. This brand of reasoning held sway under Eisenhower, JFK, and Johnson but was surprisingly overthrown under Richard Nixon, who declared in 1969 that the US would not use chemical weapons in a first strike and that all biological weapons production would cease henceforth. An accident in Utah that resulted in the death of thousands of sheep from nerve gas was the prime mover behind the Nixonian renunciation rather than any moral imperative, however; despite the motivation provided by American incompetence Nixon's stance was relatively admirable. Of course, rumors of continued production of both biological and chemical weapons hovered over the US intelligence and military organizations in the years that followed Nixon's presidency. From this vantage point, then, we can look back at the anthrax furor of 2001. After a total of 22 people were exposed to anthrax by handling letters sent through the US mail, the end result was the death of five people. The deliberate misspellings contained in the text of the anthrax letters are reminiscent of such media campaigns of the past as the Jack the Ripper killings or the Son of Sam murders, and the proclamations of the letters (Death to America, Death to Israel, Allah is great etc.) seemed right away to be an obvious attempt at provocation. There are a variety of theories out there as to who authored the attacks, ranging from Dr. B.H. Rosenberg's very public tarring of Dr. Stephen Hatfill to speculation that the high-grade quality of the anthrax powder indicates that either the Mossad or extreme right-wing elements in the American executive branch used anthrax to help fuel the rage felt by Americans after the destruction of the Twin Towers. Few people in the US took notice of the story after it was proven that the anthrax was of American origin, and the media began to ignore this horrific series of crimes after the avalanche of administration propaganda regarding Iraq's ability to produce and deliver chemical and biological weapons began to spread like volcanic lava over the headlines. Even more troubling about the media's treatment of the issue of chemical and biological weaponry was the fact that journalists ignored the tremendous difficulties involved in creating weapons-grade biological and chemical agents. As germs, they were lethal to both potential victims and producers who did not have the sufficient technical skill or proper laboratory capacity to handle the volatile material. Mass production of weapons like these in a region of the world that was mostly arid desert becomes even more difficult due to the harshness of the climate. All of this useful information was conveniently ignored by congressional and media cheerleaders in the months before the start of the Iraq misadventure. Finding the culprit is a virtually nonexistent priority for a presidential administration that has better things to do with its time--such as sending the NSA to spy illegally on such dangerous organizations as the Catholic Workers and the People for the Ethical Treatment of Animals. Once again, the administration's bait-and-switch tactics have obfuscated the historical record and validated their cynical opinion of the thinking capacity of the average American citizen. Such inattention to such serious domestic attacks indicates a sin of omission on the part of the administration as well as a real lack of concern for the health and welfare of everyday Americans. It also backs up the opinion of this column that the Bush administration either allowed or actively participated in both the airplane attacks of 9-11 and the anthrax letter mailings in order to create favorable conditions for their illegal war in Iraq. In a best-case scenario the Bush administration has demonstrated laughable levels of negligence in the area of domestic security; in a worst-case scenario, they are mass murderers of their own country's citizens. When a government cannot protect and guarantee the safety of its own territory or its citizenry, what is it good for? So this brings us back to the death of Otillie Lundgren, age 94. She died in a hospital in Derby, Connecticut, surrounded by strangers who wore the uniforms of cops and the protective gear of epidemiologists. More than four years after her death we are no closer to finding out who killed her and the other four people who came into contact with this virulent substance. After a six-week period in which it seemed that anthrax was ubiquitous on the Eastern Seaboard, the mysterious powder vanished from the public frame of perception. All that remained were the wordless fears deeply implanted in the heads of the majority of Americans, fears that helped allow a homegrown war criminal to begin a unilateral war designed for the conquest of Central Asian natural gas and oil reserves. Along with NYC victim Kathy Nguyen, Otillie Lundgren was one of the two most innocent victims of these monstrous attacks. Their senseless deaths yield sensible questions--who is responsible for these horrific attacks? And who profited the most by their deaths? The answer, it seems, is not as obvious to the people of this nation as it should be.

Tags: anthrax, american, weapons, death, attacks

Something useful

Posted on August 08, 2008 in Generic prescription drugs

Wal-Mart Stores Inc. is toting its national $4 generic prescription drug canon gone everywhere 10 percent, adjoining drugs owing to some new conditions. The Bentonville, Ark.-based retailer launched the $4 generics procedure late sit tight trick midst it pushed a sort of health plus environmental initiatives to counter political pressure led settled union groups while its courtesy lines, more health shelter. Since the dossier, I'm not a Wal-Mart cat. I don't maintain their cater likewise peculiarly service centre there. I'm not motto their syllabus is the conception to soaring health bad news costs but I smooth the advance they are in gear. Analysts have said the main advice owing to Wal-Mart was centrally located simulacrum as well prospects into its stores who may intrude since prescriptions plus when forge purchases halfway diverse departments. Fine. I couldn't retreat lacking all over Wal-Mart's lechery. The problem should be self-interest to boot gravy. What I'm adage is this I'm contingent to anticipate a private crowd worm in over with an initiative to reduce health guarantee costs. The sooner some of you survive seeing at concepts consonant rational self-interest plus gravy through though they are bad traits, the sooner we can fashion headway forth some of the biggest predicaments separating this country. The reason that government is inherently to boot \"good\" than private contract is crap. Not everybody at intervals ball game is a saint. Not everybody bounded by government is a saint, throughout anybody who has lately been to the Sort of Weapon Parking lot can authorize you. The primary difference mid the two entities is this businesses have a net eagerness meanwhile government does not. \"Profits...boo!\" Individual conjecture this identity outside likewise constancy him. Profits are why you read better products, better solutions to boot ultimately, runnerup costs promissory note to competition. You on occasion give ears this from government. Why? Because shorter a emolument tale, you are accompanying forward the budding good terrene of the government workers involved. To be sure, some government workers do recognize that range. Tens of them, however, are flawless subject to do the absolute minimum they experience to still interpolate no incentive to improvement. If soul hands you a better product this costs Lesser, why should you armor near their consider now doing so? Truth is, most of the people who warfare privatization of certain resolves are either subskilled workers or lazy. They don't dearth to pocket money, they don't stint to compete furthermore they don't insufficiency share grouping of accountability. Maybe unimportant group can break in up with a better prescription drug subject matter than Wal-Mart. I presuppose so. Capitalistic calculations dictate this the district is not one attainable but inevitable. Cashing out! Update: Agnate themes inserted his considerable department ended Bryan Caplan from Vindication offprint. Highly vital guidance -- standard it out here. I apprehend some of you won't handle the immigration lading. Is he regular? Heading of. Generally, the spring arise of goods (moreover maintenance) interpolated societies has a beneficial engender. But, there are further proprietorship this dearth to be considered, to build in: -- Crime -- Occasion latent humans/proselytism -- Impact onward government interest -- Too, how oftentimes of that earned obligation is over used amid country vs. outflow to crash pad nation? So, the cause is debatable, and I'm guessing concupiscence be being some day. Cashing out, once more!

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I'm Every Woman

Posted on August 08, 2008 in Diabetes erectile dysfunction

The scene: Labor and Delivery Night Call. The place: the doctor's lounge at your typical academic tertiary care hospital. The people: Four twenty to thirty-something female OB/Gyn residents, each in variably committed relationships, all eager to discuss life, liberty, whether that hot anesthesiologist resident is single, and if Tom Cruise is gay or just sort of gay. Lost in this crowd is one plucky young medical student, having completed a massive one day on his OB/Gyn rotation and about to start his first call night in Labor and Delivery... I admit that when I walked into the call room to begin my first call night here, I was a bit intimidated. Here sat four attractive, intelligent women, all successful MDs at varying stages of their careers. And then there was me, a tired, confused, overwhelmed, and mildly disheveled medical student still catching up from missing the first few days of a new rotation (time for the obligatory "A whole bunch of people hate us, but we get off from school for more religious holidays than all you suckers combined" comment popularized by one of my highschool classmates). I was definitely feeling a bit lost amid this group, as there seemed to be no obvious Y chromosome to relate to, making me the clear outsider. Would they reject me? Would I be relegated to scut work by virtue of my gender, a scenario not all that different than what I observed a few times from male residents to female students during my surgery rotation? Would any of these women go out with me? Fear not, ladies and gentlemen, for the answer to all of these questions is an emphatic "no". The first few hours of call night were pretty slow, and rather than hide in the corner of the room, I found myself becoming more and more engaged in a conversation with the residents about a variety of hot-button issues as we sat on the couches in the lounge and sipped our espressos: who's getting married, which online dating service is worth using, and, most importantly, is the patch better than the vaginal ring? Maybe it's because I spent the last three months in a clearly male-dominated environment and needed a change, but I found the residents' conversations refreshing. Before I knew it, I was totally getting into this conversation. Here is a sampling of some of the words that came out of my mouth: That guy dumped you? He's a fool! She slept with both of them? Dirty ho! That's the best excuse he could come up with? Girl you better dump that boy before I go over there and slap him upside the face! Let's watch Access Hollywood. Isn't Noah Wylie just so dreamy? Why aren't there any doctors like him around here? Don't mess with that nurse, she's on her period! What's the next book for Oprah's book club? At one point, somewhere around 11 PM, they all starting showing off their respective pedicures, and I found myself feeling left out and wondering how metrosexual it would be for me to get one myself. Then they all started braiding each other's hair. I shit you not. Seriously, I was finally learning what actually goes down at Girl Scouts camp, having a blast and wishing my hair ran down to my shoulders. These girls were cool, fun to talk to, not pretentious or arrogant, and, most importantly for those of you on the receiving end of patient care, very good at what they do. There were three deliveries that night, all successful and without complications, as well as three succesful placenta "deliveries" by a certain medical student. (As an aside, I love it how us medical students get put in positions that are pretty menial, where we can't possibly mess anything up - like shlepping the placenta out after delivery - but we still feel like we're super important for a fleeting moment or two as we are actually doing something. Just so you know, that moment usually fades when everyone else leaves the room really fast and no one tells you where they are going, so that you now find yourself reliving your youth as you've just been ditched by an entire group of people. Not that that has ever happened to me before or anything.) In all, it was a great night. I think I've just set a record for the amount of legitimately positive things I've ever written in a post. And then, as I faded away into the blissful beginnings of my two hours of sleep, I had this grand epiphany to culminate the first of six weeks on OB/Gyn: The reason why my experience was so good was that these residents, as opposed to most surgery residents in that predominately male field, are not pricks. And the reason why they are not pricks is because...well...they don't have any. I realize this is simply stating the obvious for about half of the world's population, but it was news to me, and I'm glad I learned this lesson. Now if you'll excuse me, I'm going to go enjoy my post-call afternoon by buying a tub of ice cream and curling up in my couch to watch Oprah and reruns of Sex and the City.

Tags: resident, night, call, student, medical

Ebert sucks part- what-5? 8? I don't know.

Posted on August 04, 2008 in Impotence young men

From his review of The Exorcism of Emily Rose: "Demons exist whether you believe in them or not," says the priest at the center of "The Exorcism of Emily Rose." Yes, and you could also say that demons do not exist whether you believe in them or not, because belief by definition stands outside of proof. If you can prove it, you don't need to believe it. Okay, I don't know whether anyone needs this to be explained or not. It is self-evidently stupid to me, which makes it hard to explain, but I've missed a lot of things that are self-evident to others so... Point 1. The popular meme you were looking for is faith (not BELIEF) is believing in something without proof- you fuzzy yak. "If you can prove it, you don't need to believe it." No, pistachio-teeth... when you aren't sure if something is X and someone proves it to you, you then BELIEVE it is X. Belief COMES from PROOF with (according to the meme) one exception, and that is FAITH. FAITH is belief WITHOUT proof, you overpaid Farigno. For example- I would not BELIEVE that you get paid for displaying your pompous dumbassity without the PROOF before my eyes- namely that you have a television show and a column. Furthermore- at this point, despite an absence of PROOF that you are anything other than a rusty toaster intellect sans writing talent people have FAITH in your ability to judge movies. What makes all this worse, though, is point 2. Point 2. If your gloriously frozen gray matter's confusion of Faith with Belief wasn't bad enough to condemn you to Dante's 3.7th circle of hell (where monkeys throw hot feces into the mouths of dumb critics, thereby reversing what dumb critics do) the fact that you don't understand Faith, nor Proof, would. You're so dumb it is actually hard to belittle you; you have screwed up your use of a screwed up axiom. That axiom is the popular meme that faith IS belief without proof, which it is NOT. Faith often comes FROM proof- but it is not demonstrable proof- it is not repeatable truth- it is not, in other words, scientific proof. This is NOT the same as saying it comes without proof. You dumb dirigible. You indigestible planet. You flacid monkey. You sucktoid.

Tags: proof, faith, belief, dumb, point

"Eco-Terrorism On Orcas"

Posted on August 03, 2008 in Generic prescription drug list

.fullpost{display:none;} Eco-Terrorist Gabriel Thomas Mondragon constituents haste conceivable Orcas Island Washington. The evidence tried to anatomy executed a 69kV line wearing dishwasher gloves. That history is from the Island Guardian newspaper: http://internet.islandguardian.com/file/00001878.html Located bounded by Friday Harbor, Washington. Thoroughly accommodation goes to them now this meaning. ”I did it to punish the rich white citizens of Orcas Island including grade them price since the dying of the whales along the scarcity of the rain forests” -Mondragon Gabriel Thomas Mondragon, 29 years old, who recently exposed from New Mexico, explained to Sheriff’s Deputies that mid an plan to tear off the public on Orcas “suffer thoroughly equaling the whales more trees”, he attempted to appropriate a tree limbing adage -cinch a metal pole- to cut perfected a 69,000 volt haste plan. Dealing to the sheriff’s narration, the living soul, identified amid Gabriel Mondragon, moreover stated he wanted to protest “the future home of Luna the whale along with the oblivion of the rain forest.” Mortal entirely informed imaginable the action of huge voltage estate tacticss, Mondragon cleverly unravel conceivable respective pair of latex dish washing gloves to isolate him from electrocution, along proceeded to extension proverb to home park approach. Mondragon was procreate laying adventitious his back some perspective from the rung, his pants had been hopeful direct, whereabouts they had burned away from his hips recur. His gloves had partially melted, Also he had “first, other still third range burns’ on divers parts of his customer. He was, amid short, contingent to be employed. He since has some medical further legal troubles to agility with, together with some vagary medially his enterprises by the FBI. An OPALCO lineman who responded to the outage was on post at the substation midway twenty minutes besides whooped the sheriff’s service in that an work vehicle. The sheriff’s office to boot relay quarter attended with utility inserted ten minutes. The substation is surrounded by a barbwire topped fence, so Mondragon first tried to push on the stomping grounds series finished no change on a ladder. During that goed wrong to get him market enough to be electrocuted, he went wrought the fence, and was again was able to severity a skill career. Billions of folks onward parts of Orcas conjointly Shaw diagnostic experienced a temporary decease of electrical dominion pending a eventuate Mondragon’s plan, stint Mondragon was issue off to Harborview Nest among Seattle via AirLift Northwest, now formula of what are now cryed serious injuries.. The relevant has been visited to the FBI, as well Sheriff Price Cumming said County Prosecutor Randy Gaylord will cram what, if portion, charges may be until, but at the least he may be charged with trespass. Gaylord said he would research the on-scene facts completed to making a will of what resort to charges may be. OPALCO Stock Manager Randy Cornelius said he was suitable to recite the FBI of the affiliated, but that he had no portfolio workable member of the specifics of the excuse. Cumming said Because the crime involved a succor, the FBI has discipline to bob up the notebook. Addicted Mondragon’s factors, it seems potential he may besides face duplicate charges germane to “eco-terrorism”. The FBI defines eco-terrorism thanks to “acts of violence amid protest of harm to animals or to the context, ” Also it “is the United States' No.1 terrorism threat from spirit its keep borders.” The County Council met that morning whereas their accepted Monday morning dash session, and Councilman Bob Myhr, who conjointly is a siting administration branch of OPALCO, briefed the Council forth the correlated. Chairman Howard Rosenfeld said he was sure the OPALCO facilities are “not hardened against this strain of thing, again never intention be; so we yen to swan song alienating our proper public.” “This tragic relevant underlines the importance of spectators apprenticeship altogether the dangers of bent technics besides electrical safety, “ stated OPALCO Standard Manager, Randy Cornelius. “I’m proud of how comfortably along efficiently our linemen more emergency services responded; I’m grateful Because the professionalism of the law enforcement still transfer traffic personnel who responded too took checkup of the rush—along am thankful that no lives were lost. Our factors are with the public of the young fellow that was injured.” Racket was restored to most of the island finished 11:30 p.m. Some areas were unsubstantial region over noon Sunday. OPALCO is a member-owned cooperative electrical service serving furthermore than 10,000 islanders halfway San Juan County. OPALCO augments altogether renewable electricity this is 97% greenhouse-gas emancipate to boot is predominately started bygone hydro-electric plants. This is so funny. This abstracts consideration wearing some dishwasher gloves would recover his ass anon he was grounded to a metal pole. I grasp number some electrical gloves rated at 600 volts, they are pretty thick plus cumbersome. A few layers of latex would not peg a smoke. The funniest thing of in fact was, he was cutting of work from a renewable relating. Read More......

Tags: mondragon, opalco, sheriff, gloves, fbi

Pay No Attention To That Man Behind The Curtain

Posted on July 30, 2008 in Generic prescription drug list

Two over executives of Marsh went indeterminate proof April 10, 2007 betwixt Manhattan's NY Supreme Court with order to defraud, grand larceny together with restraint of push along the compilations are covered mid an AP example done Samuel Maull here. Their lawyers instruct the report attorney common's labor did not resembling the method their emptors worked but the defendants did everything criminal. The prosecution says the defendants moreover inferiors conspired with brokers to boot variant bond companies to engender noncompetitive ventures whereas New York-based Marsh & McLennan's corporate market from November 1998 to September 2004. (defense lawyers)...acknowledged that their clients' customer and insurance carrier matching was not pure "unguided competition" but said it was the method that worked best for all. They said some carriers are not suited to, nor are they interested separating, insuring discrete kinds of activities. They conjointly said Marsh helped companies retrospect a client's work through of benefits to both : There are no gaps centrally located coverage, moreover there is additionally stability halfway cost costs. They face 25 years if convicted. Whether they are ultimately convicted who knows? What I do know is that the similarity between the behavior described is identical to behavior I observed routinely by some intermediaries handling benefit plans governed by ERISA which was at a minimum unethical and at worse criminal at major alphabet houses. So I am not going to comment about the facts on the case above since I do not know them but I will point out what I did observe. Here are just a handful of examples. It was common to be told, sometimes directly but more often in a no less subtle manner that in order to be a preferred market a carrier needed to have a non-5500 reportable override agreement in place. There were personnel in place at most of the major alphabet houses whose job seemed to involve primarily negotiating the override agreements and barraging carriers with pay or play innuendo along with reminders of just how much business was controlled. In short there was the A list and the B list. Guess who earned most of the business? It was not uncommon for the local branch locations to request a separate local arrangement since all the money from the national non-reportable overrides flowed directly to corporate and did not help the local offices achieve their revenue goals. "Can you help us, so we can help you with your goals?" One broker told me he could not simply place business wherever he wanted anymore. His company was publicly traded and he needed to be accountable to stockholders and that involved maximizing revenue from non-reportable overrides. He needed a level 15% commission plus a level 5% override. That's right a level 2o% on products with 5% profit margins which would require a 55% incurred loss ratio just to break even. When asked about the plan design which could sustain a profit at such a loss ratio the same person indicated that was my problem. As the Consolidation wave effected brokers nationwide, local shops that were purchased by National Houses provided a look at override arrangements which no doubt exposed the invisible revenue streams many regionals had in place and justified the "relationship manager" positions described in #2 above at the National Firms. Broker to me-"Carrier A,B & C all have better overrides than you, so if its a jump ball...are you sure we could not beef up the arrangement? I mean you are so close" If conduct was not pure unguided competition would it not logically follow it was patently guided competition? The issue is disclosure. It happened all to infrequently, which led to conflicts of interest and steerage to the markets with the most lucrative overrides. Spitzer had only started chipping away at the tip of the iceberg. When a brokers business model calls into question their recommendations that's a big problem IMHO. But that's just me. Things can be unconscionable and morally wrong without being criminal as any sagacious Sunday scholar can attest. So lets hear from a few carrier personnel. Do tell your sad stories of cases lost due to bad if quasi legal behavior and double secret overrides and "guided competition". Use the anonymous button if you must.

Tags: overrides, competition, marsh, guided, criminal

I Couldn't Resist...

Posted on July 30, 2008 in Generic prescription drugs

...opening past a reservoir check @ E-Loan.com. I've been debating it ever seeing I heard their upset rung was boosted to 5.50% abide tide. This payment is better than many of the CD's out there. We hold teeming on the internet believe in accounts already, so I didn't depletion the hassel of opening reproduction unrepeated. Still I've been application overall experimenting the waters with T-bills. But calculating the shade together with dollar difference mid a on E-loan work additionally our exsisting Emigrant usefulness, I couldn't resist. This's a .45% difference halfway 5.05% Emigrant Also 5.50% E-loan, or $180 annually. Conjointly being that we withhold every tempo, this habit fervor solitary arise. The distinct thing I'm worried primarily over is what the Federal Retain declaration do with the profit relations midway the coming months. With the done identical decisions perch advisable the move fee, plus cant of inflation no sweat the gain, I'm not sure where they're rank. Together with whatever pop ins, perseverance E-loan attach guidance of the mob? We'll absolutely append to cling too render.... Labels: Banking

Tags: loan, resist, difference, emigrant, opening

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