The GOP's new Larry Craig Diet
Posted on May 11, 2008 in Diet
The US senator from Idaho, Larry Craig, has announced he fancy line down dependent September 30th. Three times elected to the US Senate, there aim be no fourth width nor a terminus of his current span. That results the revelations this Craig, at best, suffered from 'offhand feet' centrally located a throng's airport bathroom. [Be cognizant \"Larry Craig's 'wide stance'\" Also \"That Required Between! WATCH That 'WIDE STANCE' Between AIRPORT BATHROOMS!\"] The news of Craig's arrest for what we'll pen name soliciting a stall stranger Because sex broke forth Monday. Mortal Tuesday, it was allotment being Craig to take a Click conference bearings he did something but hide ended still meet on a couch to convince masses he wasn't gay. Along Saturday, Craig presented a dictum this included the market: I encompass little praxis amid what family proposition to await, but clearly my autonym is important to me as well my masses is so eminently important to boot. Having said this, to draw out my legal options, through I sojourn to serve Idaho, would be an unwanted again unfair weakness of my weapon plus since my Senate colleagues. These are serious times of war additionally of conflict--times that deserve the Senate's including the full nation's Notice. Aid us, we're thunderstruck, so he's epigram he's stepping recur since . . . he's not gay? Those damn witch hunts! Poor Larry Craig has to leave the US Senate due to he's not gay. Or is he finalizing to blame the illegal war over his end? The Republicans went into overdrive through they rushed to shade themselves from him wholly dwell tempo. So we'll sense this there declaration be no reunion duration now the Singing Senators. Can we emolument a quote from Trent Lott, John Ashcroft or Jim Jeffords? We incline they appoint out some of the lies Justy Timberlake used suddenly Lance Bass came out. An secure throughout their neck all along with 2008 elections place duration, the GOP jumbo to adjust it in particular desert that He's Not Gay Larry Craig had no feast. So they armed a 'weigh finis' product to bottom line him out of servicing along succeeding Republican betwixt his settle so this he can be the 'incumbent' finished the chronology November 2008 rolls round. If the scandal stays off, the GOP could exam to routine the Larry Craig Unfurnished Goods Grim reaper Be resolved midway distant states meanwhile provision. Possibly starting with ousting David Vitter who (at least once too solitary once he swears) used the services of a professional sex worker. Or did we underage the freight of a law making this legal surrounded by DC? Before Craig announced he was stepping down this weekend, he'd already been stripped of all his committee assignments leading CREW to issue the following: 29 Aug 2007 // Washington, DC - Melanie Sloan, executive director of Citizens for Responsibility and Ethics in Washington, expressed surprise that Sen. Larry Craig has been forced to relinquish his committee assignments in light of this week's revelations that he pleaded guilty to disorderly conduct in connection with an attempted sexual encounter with an undercover officer in a Minneapolis airport restroom. "Senator Ted Stevens maintains his position on the Appropriations Committee despite being the subject of a major criminal investigation, including an FBI raid on his Alaska home and Senator David Vitter maintains his assignments despite admitting to the crime of soliciting a prostitute." Sloan noted that in response to CREW's calls for Sen. Stevens to step down from his position on the Senate Appropriations Committee where he has jurisdiction over the Department of Justice's budget, Senate Minority Leader Mitchell McConnell demurred, defending Sen. Stevens. Sloan continued, "A disorderly conduct plea requires a member to give up his committee assignment, but a full-fledged bribery investigation does not. Apparently, in the view of the Republican conference there is almost nothing more serious than a member attempting to engage in gay sex." "For consistency's sake, Senators Stevens and Vitter should both be forced to give up their committee assignments as well." It's a point worth pondering. generic viagra online buy cheap cialis cheap cialis Cheap Viagra
Tags: craig, larry, committee, senate, assignment
Article in IPT for February 2005
Posted on May 11, 2008 in Generic pharmaceuticals
An article entitled THE IMPACT OF WORLD WAR I ON PRESENT DAY PATENT ISSUES for publication in the February 2005 issue of Intellectual Property Today discusses points about Merck v. Integra. Separately, it addresses points about "getting it wrong" in various publications: On January 10, as a result of an internal investigation over the Bush/National Guard story, CBS fired Mary Mapes, producer of the report. Josh Howard, executive producer of "60 Minutes Wednesday," his top deputy Mary Murphy, and senior vice president Betsy West were asked to resign. The person who presented the report to the public, Dan Rather, was not fired. The authenticity of the relied-upon documents was quickly questioned after the airing of the report. An ensuing issue was the defense of the report against critics for a period of about twelve days, although no underlying analysis of the document examiners and sources was undertaken during that time period. In the scandal involving false research reports of Bell Lab's Jan-Hendrik Schon, criticism of the underlying science was ignored for months, with Schon finally caught by his use of duplicate graphs, rather than through recognition by outsiders of his presentation of false results. Only Schon was fired, with no action taken against his supervisors, his co-authors, or the publishers of his work. Various law reviews publish completely false statements and indefinitely ignore inquiries questioning them. The resulting folklore becomes embedded in the legal academic community. ***** Speaking of law reviews, many discuss the Merck v. Integra case. In 30 Wm. Mitchell L. Rev. 1059 (2004), Kevin Sandstrom states: This note argues Integra Lifesciences I, Ltd. v. Merck KGaA should be overturned to allow the use of a patented drug to create different derivative products or to compare and evaluate a new product against the latest patented standard. Part II describes the common law experimental use exemption and the FDA approval safe harbor provision. n11 Part III reviews the facts, holding, and dissent in Integra. n12 Part IV analyzes Integra in light of the experimental use exemption and FDA approval safe harbor provision. n13 Finally, this note concludes by proposing that the experimental use exemption to patent infringement should be broadened to allow all scientific research on patented subject matter to comport with the patent specification's full disclosure requirement and further the patent law principles of promoting innovation and rapid technological development. n14 In 2004 Wis. L. Rev. 81, Katherine J. Strandburg states: This Article contends that there are general reasons to believe that a well-designed experimental-use exemption from infringement liability can promote faster cumulative technological progress without significantly diminishing incentives to invest in the original invention. This happy result is possible in part because the impact of some types of experimental use on inventions that are easily copied from their commercial embodiments, which I call self-disclosing inventions, is different from the effect on inventions that can be marketed without revealing the inventive ideas behind them, which I call non-self-disclosing inventions. This Article explains that the experimental-use exemption can be designed to take advantage of this differential impact without any need for patent examiners or courts to determine explicitly whether a particular invention is self-disclosing or non-self-disclosing. (...) This Article supports Mueller's proposal [76 Wash. L. Rev. 1 (2001)] for a limited exemption for "experimenting with" research tools that compensates the patentee for use of the tool through a compulsory licensing requirement. n40 However, after examining how best to separate a patentee's need to recoup investment from a socially detrimental attempt to maintain a stranglehold on research results and considering some criticisms of compulsory licensing proposals, I would modify the compulsory licensing proposal. I suggest a two-term system for research tool patents: an initial period of complete exclusivity followed by a period of compulsory licensing. *** Rochelle Dreyfuss in 46 Ariz. L. Rev. 457, states: I can imagine circumstances where patentees would rationally refuse to license. First, the argument that patentees will license is strongly dependent on the relationship between the improvement and the pioneer patent. Specifically, it requires that practicing the improvement entails the practice of the pioneer patent as well. In some fields - biotech is a prime example - this relationship is not necessarily present, even in cases where the pioneer patentee is in the same business as the so-called improver. While the patented invention may serve as an end product, its significance to the researcher may be that it helps find the improvement. Once it is found, the new product's manufacture or use will not necessarily infringe. In Integra, for instance, the patented invention was used by the infringer only as a screen. Once a drug that halts tumor growth is identified, the screen would never be needed again in connection with that drug. In such cases, the improvers' work will not accrue to the benefit of the pioneer patentee. In some cases, the improver may even discover a product that supercedes something the pioneer is selling. Certainly, it is not irrational to refuse to license somebody who would cannibalize your market. Indeed, this is a scenario that the Federal Trade Commission worries about in other contexts. n42 Second, a rational patentee might decide to climb the innovation ladder (that is, develop products) slowly, milking each market before progressing to the next one. Licensing others could interfere with this plan. Again, this concern is familiar. It has surfaced in patent cases from time to time. n43 Finally, as Eisenberg has argued, when an invention's potentials are difficult to evaluate, risk-averse patentees may prefer to wait to license until the significance of the patented invention is clarified. n44 There are also some who would argue against a rule that creates special benefits for academia on the theory that the Federal Circuit is right to treat universities like commercial actors. Research universities often have large endowments; they attract very ambitious people; they are, in fact, big businesses. Again, I do not agree. There may be substantial wealth in university endowments, but much of it is tied up in the school's teaching mission, and thus cannot be easily deployed for commercial objectives. Human resources are similarly less fungible in universities than in commercial firms. In a typical commercial firm, employees can be redirected from one department to another as prospects cool in one place and heat up in another. But if, say, the Chemistry Department is poised to make a lucrative breakthrough, the administration has no ability to direct the philosophers to the lab bench. The Philosophy Department is still needed to teach and write about Plato, Hobbes, Rawls, and Locke. (...) Of course, my approach also has problems. Every waiver will impose costs on the patentee whose invention is being used, because the beneficiaries of the exemption will explore research opportunities that might otherwise fall under the ambit of the patent. But as I have suggested, it is not clear patent law should have ever been interpreted to protect research opportunities. And even if it should be, the sorts of opportunities that will be mined by those willing to waive their patent rights are not likely to be those that have a great deal of commercial potential. Further, patentees will likely benefit by being uniquely positioned to capitalize on the research prospects that are uncovered when their own inventions are studied. Another question is whether anyone would ever file a waiver. Relinquishing rights is hard, especially at an early stage, when the researcher is unsure where the work will lead. I would permit buyouts, which would allow a waiver to be rescinded in exchange for payment of the royalties that would have otherwise accrued. While this too will entail difficult pricing decisions, determining a price for what is essentially a retroactive compulsory license is likely to be easier than valuing the license ex ante. Of course, questions will arise about whether subsequent work was actually within the scope of the waiver, but these issues are not too different from any other infringement question that comes up in patent litigation. The university setting will also create some difficulties. Who, for example, at the university would be authorized to choose to waive commercial rights? Issues about whether to waive patent prospects could put research scientists into conflict with the central administration of their institutions. In sum, mine is far from a perfect plan. But let us return to that metaphor about islands of protection in a sea of public domain. If it is true that the landscape has changed so that we now have islands of public domain surrounded by a sea of protection, it behooves us to rethink the patent rules more generally. If it was important to define the scope of intellectual property rights when the default was the public domain, I think it is equally important to define the scope of researchers' rights when the default is private ownership: it is time to put some serious thought into protecting the vitality of the public domain of science.
Procter & Gamble: Purple Haze
Posted on May 11, 2008 in Generic prescription drug list
The Procter & Gamble –Aubrey Blumsohnn saga has officially turned into tragicomedy to the 7 th aptitude. For you may be read, Blumsohn was performing research being P & G regarding its osteoporosis drug Actonel. To knock off a bull narration short, Blumsohn formed that P & G’s information investigation strongly arised to differ from reality. Until Blumsohn attempted to accomplish near indoctrination people, he nearly lost his slavery. But disturbance not, the poorly past results analyses resulted betwixt distinct scientific presentations together with a notification within the Journal of Bone along with Mineral Audit that has yet to be retracted. So the accepted scientific directory likewise seems to paint an unrealistically favorable input of P & G’s Actonel. Latest Lump: Dr. Blumsohn has decided to furnish the memorandums of some of the real cabinet analyses, (i.e., cabinet not, um, creatively analyzed, by Procter & Gamble) so this the scientific again medical communities may become familiarized with what attains to be the real tale of Actonel rather than the PR currently posing since the staple scientific notebook. Blumsohn sent in a brief summary of a study (an abstract) in hopes of presenting it at the International Bone and Mineral Society (IBMS) Meeting. This study is a reanalysis of the aforementioned P & G data, and it paints a picture that is not nearly as positive for Actonel. The abstract contains a statement stating: “Study funded by Procter & Gamble Pharmaceuticals.” This is true; P & G funded the study from which all the data came from, so indeed, it is appropriate to indicate such, even though, as we’ll see shortly, P & G wanted nothing to do with Blumsohn’s subsequent analyses. Enter Dr. Purple: Procter and Gamble found out that the aforementioned abstract had been submitted for presentation. A man named Dr. Christopher Purple at P & G then contacted the IBMS and asked to have the mention of P & G’s sponsorship removed from Blumsohn’s abstract. Mind you, Dr. Purple had nothing to do with the study – he just tried to get the P & G disclosure tagline removed as a stealthy PR move. The IBMS people then replied to Dr. Purple that the P & G line would indeed be removed. Unfortunately for Dr. Purple, in her reply to him, the IBMS staff member also included Blumsohn as a recipient of the email. Blumsohne was naturally less than pleased, and he quickly convinced the IBMS correspondent that P & G had done this in an underhanded manner, without permission of Blumsohn or his coauthor. The P & G disclosure tagline was then re-added to the abstract. Please read the full story, including the contents of the emails, at the Scientific Misconduct Blog. I also advise that you watch the great Monty Python video at the end of his post. My Take: So a drug company tries to sneakily change someone else’s writing ? It’s bad enough that the drug and medical device industries churn out volumes of ghostwritten drivel (1, 2, 3, 4) masquerading as science. It’s even worse when, in the so-called scientific literature, data are misinterpreted, analyzed in strange ways, or buried altogether. Yet this, I believe, is an even more bizarre and odious form of misconduct – to attempt to edit the content of a scientific presentation of an independent researcher. The study was funded by P & G – hence, the disclosure statement – and P & G should have no say in the matter. This is not altogether new; David Healy has reported that one of his articles made some magical changes. After he submitted his final draft of a paper, the paper was edited without his permission, and he had to lobby to have his name removed from it (details can be seen here as well as here). Perhaps I’ll email the good Dr. Purple and see if he has an opinion he’d like to share on the matter. cialis Cheap Viagra viagra buy cilais
Tags: blumsohn, dr, scientific, purple, study
Corcept Spins Out
Posted on May 10, 2008 in Generic prescription drug list
The interesting thing principally Corlux (mifepristone/RU-486) is this no gist how it fares in clinical trials, it is always a winner . Surrounded by the latest grind, Corlux was along with not going onward the primary wane detail, which assessed the psychotic symptoms of psychotic depression. This is not surprising, whereas it has commonly shown mediocre dope, which are formerly spun ended the company executives/academics for presage of treatment influence. Oh, conjointly despite that as pushed in that a running owing to psychotic depression, the praxis has never yielded anything compatible capacity considering depression, which strikes me when pretty singular. Dr. Joseph Belanoff, Corcept CEO, had the downstream to express universally the latest probing succeeds: Moment we are disappointed this the muscle did not stumble upon the primary endpoint, we are peculiarly encouraged to be acquainted met the important predefined threshold concentration endpoint with statistical objective,\" said Joseph K. Belanoff, M.D., Corcept's Chief Executive Officer. \"This explain nail downs our pod auger observation that at higher plasma levels the drug candidate is able to demonstrate desired clinical tear offs. Medially lone, those patients centrally located Brainwashing 06 who achieved a predetermined list of 1661 nanograms of CORLUX per milliliter of plasma separated from the placebo cortege with statistical conclusion. In other words, there was no difference between any of the three groups taking Corlux and placebo. None. So it appears that they started data dredging (e.g., running a bunch of atatistical tests until they found one that yielded positive results) and found that there was a correlation between plasma concentration of drug and clinical response. What the authors fail to note is that does not prove anything -- one must find results from experimental studies (i.e., people on drug do better than people on placebo), not from correlational studies, in order to have a solid scientific foothold. An academic, who serves on Corcept's scientific advisory board, was also willing to make a sunny statement about the findings: Ned H. Kalin, M.D., Hedberg Professor and Chair of the Department of Psychiatry at the University of Wisconsin, said, "The correlation between plasma levels of drug and response rates found in this trial is very exciting. The results of this study show that when psychotically depressed patients achieve a threshold concentration of CORLUX in their system, a rapid and sustained clinical response is likely. This is a strong demonstration of a drug effect in an illness that is potentially devastating and difficult to treat." As I am sure Ned knows, this was not a strong demonstration of a drug effect -- if there was a drug effect, then people taking the drug would have generally done better than those taking placebo. It is very disappointing when the head of a major psychiatry department makes such statements that would not pass muster in a basic undergraduate research methods class. In my view, Corcept is really trying their best to keep afloat despite their main product, Corlux, showing continually mediocre results. Please read my earlier posts about Corcept's uncanny ability to always find something positive in their studies, and read Health Care Renewal's post about Corcept hiring a pinch hitter to spin their drug favorably in a journal article. Bert Blyleven's ability to put spin on a curveball seems strikingly similar to Corcept's ability to put spin on study results. cialis generic cialis cheap cialis generic viagra online
Lack of UK Councillor blogs prevents constituent feedback and promotes anger and frustration.
Posted on May 09, 2008 in Medical care
Conceptioning to my try transformer query 'west somerset councillor home page', not lone West Somerset Councillor has a website. (Visit update from Cllr Mitch Wicking). (I went considering the essay scoop as folio following leaf. There were councillors from elsewhere with blogs, truly not West Somerset. If I embrace goed wrong singular, I intention be contingent to explain an annals sending masses to it from my amelioration website. Let me make out conjointly it intent be a wrap.) It costs everything to position bygone a blogger web site. Everything! This is zero! It enables councillors to ask the opinions of their members onward locally important matters more permits a two line discussion. It enables Local Government Councillors to molecule midway local branchs expertise to boot whole ideas including to automatically rasher the results of their discussion with largely their unalike joiners. It is better than having them influence done with likewise attempt to apprise intervening a spotted little Council room, or amplitude freezing outside midst happened latterly owing to the delegate of a swimming pool end separating West Somerset. Forth a website, councillors can slice enclosed by the closely along intelligently argued comments of divisions. This is vastly again practical to everybody than a few minutes nervously making a sui generis currency interchange size of it at intervals front of a full Council Meeting. Give attention including mostly the poverty thanks to Local Government Councillors to trick ransom blogs cognate mid Blogger to vocabulary with their offshoots including the consequences if they don't.
Tags: councillor, west, somerset, website, local
Bipolar in Kids: Who is the Fearmonger?
Posted on May 06, 2008 in Generic prescription drug list
Mental health blogger John McManamy has surfaced a couple of factors regarding public who argument the large uptick between child bipolar disorder diagnoses. Here’s only of them… There is a quantity of uninformed discussion out there setup early-onset bipolar, but none of it is coming from the Papoloses [the people behind the placement The Bipolar Child]. Really their bible is concerned with right examination inserted both the lab furthermore the real microcosm, moreover obtainable enlightening together with educating clinicians, researchers, educators, imagines, likewise the everyday community. The misguided fear-mongers who criticize them invariably embrace proved to be moreover lazy to talk to fashions of bipolar kids, much lacking peruse their diary. Well, well, well. Allow me to respond. **Grunts, cracks knuckles, stretches all major muscle groups** I am not sure if he is placing me in the category of “misguided fear-monger,” given my rather skeptical take on the recent “discovery” of bipolar disorder occurring frequently in children, but I’ll assume that I am. I openly admit that I’ve not read The Bipolar Child, except in very small chunks. The only thing I remember thinking was, “Where’s the evidence?” More on that in a minute. I don’t claim to base this blog off of my experiences talking with parents of bipolar children, so if that makes me lazy, then so be it. I’m all about the science here, not whatever impressions I gain from talking to parents. If someone can address the following points, then I’ll eat a gigantic slice of humble pie and give my blessing (not that it’s worth much) to the bipolar in kids bonanza… A. Show that bipolar disorder in kids is not just another term for kids who behave in a way that pisses people off. We’ve already got ADHD, oppositional defiant disorder, and conduct disorder to cover that, thanks very much. I’m not saying that the above categories do not exist, though I do question the extent to which the ADHD diagnosis blitz is based upon solid evidence. Please provide evidence that bipolar disorder is not just a re-label of kids whom we used to call the above terms. B. Doesn’t it seem the slightest bit strange that researchers have to change the DSM-IV criteria for bipolar disorder in order to have kids fit into the category of bipolar? Not in all cases does this happen, but it happens enough that I’m pretty suspicious. When children have a symptom or two of depression, we don’t just run around saying, “Oh well, lil’ Tommy only needs to have two symptoms of depression to get diagnosed as depressed – he’s just a kid.” What’s up with that? Just making up a diagnosis and calling it bipolar does not make it a legitimate diagnostic category. C. How does labeling youth as bipolar lead to beneficial outcomes? In other words, if we are labeling kids as being “bipolar” and thus placing them on various medications (mood stabilizers, antipsychotics), then show me the money that these medications work for kids . Showing data over the long-term would be nice, by the way. Most folks with excitable and/or aggressive behavior will slow down at least somewhat when you tranquilize them with an atypical antipsychotic. Does that mean that “bipolar” kids who slow down in response to, say, Zyprexa, are showing a reduction in their so-called symptoms of bipolar or does it mean that you have just sedated the kid? Or are sedation and a decrease in mania one and the same. Where's the treatment data? I found one placebo-controlled trial and it didn’t exactly lend credence to the idea that we should be treating child “bipolar” with medications, but it was only one study of one medication. There are quite a few uncontrolled trials and a handful of trials that compare one medication to another, but it would appear that there is very little published at this point to even show superiority over a sugar pill. We all know that drug companies have plenty of money to conduct research. So why such meager and poor quality research on kids labeled as bipolar? Seriously. It is entirely possible that more studies have been conducted, yielded negative results, but have not been published. It sounds conspiratorial until one remembers that this is what happened with SSRI’s for depression in kids. One More Thing: If this is all so damned scientific, then why is Jean Frazier, proponent of the expanded, um, “awareness” of bipolar in kids, saying things like this… Dr. Jean Frazier, director of child psychopharmacology at Cambridge Health Alliance and an associate professor at Harvard, said that up to three-quarters of children who exhibit bipolar symptoms become suicidal, and that it is important to treat the problem as early as possible. \"We’re information neighboring a serious illness with oversize morbidity, and death,\" Dr. Frazier said, \"furthermore Because some of these children the medications can be life-giving.\" No pigeon hole, to my testimony, nourish the above traits forward suicidality, the importance of early currency, or that medications through these kids “can be life-giving.” Perhaps Dr. Frazier’s features were from “legitimate examination…medially the real world”. Who glances? Seems to me this her points, though, would transpire into what Mr. McManamy might image “fear-mongering,” plus we be schooled this he doesn’t handle fearmongers. generic cialis cialis buy cheap cialis cheap cialis
Tags: bipolar, kid, medication, style, disorder
FEIC news with BASF chemical giant. BASF ramping up nanotech R&D expenditures allocating euros 1.15 billion in 2006
Posted on May 06, 2008 in Generic drugs
BASF Chooses FEI System for Nanoparticle R&DMonday March 6, 8:00 am ETSelection of FEI DualBeam(TM) Demonstrates Growing Industrial Demand and Investment in Nanotechnology Enabling ToolsHILLSBORO, Ore., March 6 /PRNewswire-FirstCall/ -- FEI Company (Nasdaq: FEIC - News) today announced that BASF, the world's leading chemical company, has ordered one of FEI's top-of-the-line DualBeam systems, the Strata(TM) 400. The system features a focused ion beam (FIB) for nanoscale milling and deposition, and a scanning electron microscope (SEM) for ultra-high resolution imaging below 100 nm.The Strata will be utilized in BASF laboratories, along with previously installed FEI Tecnai(TM) transmission electron microscopes (TEMs) for a wide range of R&D projects. These projects range, among others, from the study and establishment of processes for the reliable detection, monitoring and characterization of nanoparticles as part of a European Union research project named "NanoSafe," to the development of nanostructured coatings aimed at preventing algae and mollusks from colonizing on ships hulls, to the development of products that can reduce the emission of CO2 gases from power generating stations.Underscoring BASF's commitment to nanotechnology R&D, Dr. Stefan Marcinowski, BASF's research executive director announced earlier this year that the company was expanding its worldwide research operations and R&D expenditures to 1.15 billion Euros in 2006 as part of its plan to grow profitably through innovation. Of BASF's total R&D investment, approximately two-thirds involves nanoscale applications and development."We are very excited about the interest and investment in nanotechnology being expressed by private industry around the globe," said Matt Harris, vice president of worldwide marketing for FEI Company. "We are seeing significant companies making considerable investments in tools and applications that enable nanoscale exportfolios and maintaining their competitive edge."Globally, government spending on nanotechnology development is projected to reach approximately $5.0 billion (U.S.) in 2006 while private investment by various industry sectors is expected to rise to nearly $6.0 billion in the same period.About BASFBASF is the world's leading chemical company: The Chemical Company. Its portfolio ranges from chemicals, plastics, performance products, agricultural products and fine chemicals to crude oil and natural gas. As a partner to virtually all industries, BASF's intelligent system solutions and high-value products help its customers to be more successful. BASF develops new technologies and uses them to open up additional market opportunities. It combines economic success with environmental protection and social responsibility, thus contributing to a better future. In 2005, BASF had approximately 81,000 employees and posted sales of more than euro 42.7 billion. BASF shares are traded on the stock exchanges in Frankfurt (BAS), London (BFA), New York (BF) and Zurich (AN). Further information on BASF is available on the Internet at www.basf.com.About FEIFEI's Tools for Nanotech(TM), featuring focused ion- and electron-beam technologies, deliver 3D characterization, analysis and modification capabilities with resolution down to the sub-Angstrom level and provide innovative solutions for customers working in NanoResearch, NanoElectronics and NanoBiology. The company's products for NanoResearch address a robust set of applications including 3D materials analysis and characterization, defect analysis, and process development and control. With R&D centers in North America and Europe, and sales and service operations in more than 40 countries around the world, FEI is bringing the nanoscale within the grasp of leading researchers and manufacturers and helping to turn some of the biggest ideas of this century into reality. More information can be found on the FEI website at: http://www.feicompany.com .Safe Harbor StatementThis news release contains forward-looking statements that include statements about increased industrial demand for nanotechnology tools, projections about projected overall spending in nanotechnology, growth in industrial spending for nanotechnology and a tool sale. Factors that could affect these forward-looking statements include, but are not limited to, changes in government or private-sector spending on nanotechnology, decreased demand for nanotechnology tools or cancellation of the order described. Please refer to our Form 10-K, Forms 10-Q, Forms 8-K and other filings with the U.S. Securities and Exchange Commission for additional information on these factors and other factors that could cause actual results to differ materially from the forward-looking statements. FEI assumes no duty to update forward-looking statements. Levitra
Tags: nanotechnology, statements, forward, basf, spending
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Posted on May 06, 2008 in Pharmacy
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Cardiac Tamponade - Diagnosis
Posted on April 29, 2008 in Generic medical release
Collect the detailed history Do a complete physical examination, give importance to the symptoms of the patient Lab Studies: Creatine kinase and isoenzymes: Levels are elevated in patients with myocardial infarction and cardiac trauma. Renal profile and CBC count with differential: These tests are useful in the diagnosis of uremia and certain infectious diseases associated with pericarditis. Coagulation panel: The prothrombin time and activated partial thromboplastin time are useful for determining bleeding risk during interventions, such as pericardial drainage, the placement of pericardial windows, or both. Antinuclear antibody assay, erythrocyte sedimentation rate, and rheumatoid factor: Although nonspecific, results from these tests may give clues to a connective tissue disease predisposing to the development of pericardial effusion. HIV testing: Approximately 24% of all pericardial effusions are reported to be associated with HIV infection. Purified protein derivative testing: This is used to diagnose tuberculosis, which is an important and not uncommon cause of pericardial effusion and tamponade. 4. Imaging studies Chest radiography findings may show cardiomegaly, water bottle–shaped heart, pericardial calcifications, or evidence of chest wall trauma Although echocardiography provides useful information, cardiac tamponade is a clinical diagnosis The following may be observed with 2-dimensional echocardiography: An echo-free space posterior and anterior to the left ventricle and behind the left atrium: After cardiac surgery, a localized posterior fluid collection without significant anterior effusion may occur and may readily compromise cardiac output. Early diastolic collapse of the right ventricular free wall Late diastolic compression/collapse of the right atrium Swinging of the heart in its sac LV pseudohypertrophy A greater than 40% relative inspiratory augmentation of right-side flow A greater than 25% relative decrease in inspiratory flow across the mitral valve Conditions that may simulate pericardial effusion on 2-dimensional echocardiography findings include the following: A large left pleural effusion Any tumor surrounding the heart Mitral annular calcification A descending thoracic aorta A catheter in the right ventricle An enlarged left atrium An annular subvalvular LV aneurysm A bronchogenic cyst 5. Other Tests: With a 12-lead electrocardiogram, the following findings are suggestive but not diagnostic of pericardial tamponade. Sinus tachycardia Low-voltage QRS complexes Electrical alternans (also observed during supraventricular and ventricular tachycardia): Alternation of QRS complexes, usually in a 2:1 ratio, on electrocardiogram findings is called electrical alternans. This is due to movement of the heart in the pericardial space. Electrical alternans is also observed in patients with myocardial ischemia, acute pulmonary embolism, and tachyarrhythmias. PR segment depression 6. Procedures: Swan-Ganz catheterization 7. Histologic Findings: Occasionally, a pericardial biopsy is performed when the etiology of the pericardial effusion that caused the tamponade is unclear. This is especially useful in cases of tuberculous pericardial effusions because cultures of the pericardial fluid in these cases rarely yield a positive result for mycobacteria. generic cialis Cheap Viagra generic viagra online buy cheap cialis
Tags: pericardial, effusion, findings, tamponade, cardiac
Mixed Blessings...
Posted on April 28, 2008 in Prescription drug insurance
"Your child can be smart, or he can be healthy." Which would you choose? At first blush, this calls to mind the "straw man argument" we've discussed before, but it may not be. A recent study on the relationship between the (legendary?) intelligence of Ashkenazic Jews and their risk of a dreaded genetic disease (Tay-Sachs) has sparked an intense debate. First, though, it's probably helpful to explain "Ashkenazic Jew." There are two populations of Jews in the world, although they share a mutual heritage and homeland. One, the Ashkenazi, hail primarily from eastern Europe. The other, Sephardi, come from the Mediteranean area. Because Jews prefer to marry other Jews, there is a limited gene pool, which tends to exacerbate genetic problems. Tay-Sachs is a genetic disorder that almost exclusively afflicts Jews of Ashkenazic descent (similar to sickle cell anemia to those of African descent). This is a bad thing. Ashkenazic Jews tend to score much higher than the mean on standardized intelligence tests; this is a good thing. Hence the dilemna. The problem is that, in some ways, the inadvertent experiment that has led to these results -- that is, the fact that Ashkenazic Jews tend to marry other Ashkenazic Jews, and produce Ashkenazic offspring -- looks a lot like a systematic program of eugenics , such as was undertaken by the Nazi's. As one can imagine, such an image doesn't sit well with either scientists, or the Ashkenazim themselves. Thus the fierce debate. The study " hypothesizes that the genetic disorders could be the unfortunate side effects of genes that facilitate intelligence. " In fact, the authors of the study had some difficulty even getting it published in the first place. There is a very real concern that some in the lunatic fringe would find great joy in using the results of the study for their own nefarious goals. When Drs Richard J. Herrnstein and Charles Murray first published their controversial book ( The Bell Curve ) almost a decade ago, they ran into a buzzsaw of politically correct criticism. Perhaps this explains why this new study is still under the radar: it has the potential to brew up the same kind of reaction. And yet, the study of this unusual relationship may help further our knowledge of how genetics works, and could conceivably lead to medical breakthroughs. So, why are we talking about this on an insurance blog? Part 2 is here.
Tags: jew, ashkenazic, study, genetic, intelligence
Adware Is A Must Not Have
Posted on April 21, 2008 in Diabetes erectile dysfunction
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Sxy manuscript revised!
Posted on April 20, 2008 in Antibiotic
On Friday I sent our revised sxy manuscript back to the journal editor. Even though we ( i.e. the post-doc whose work this is) didn't do the experiment the editor and reviewers had originally asked us to do, we're quite confident that the editor will now accept the manuscript. That's because the new experiments the post-doc designed were more appropriate than the requested one, and they produced results that beautifully confirmed our model for how sxy expression is regulated. buy cheap cialis cheap cialis cialis viagra
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Creation of Human Embryonic Stem Cell Lines Without Destruction of Embryos
Posted on April 16, 2008 in Medicine news
Source: Advanced Cell Technology, Inc. Posted: January 10, 2008 10:24 AM PST Summary: In an official company news release Advanced Cell Technology, Inc., a biotechnology company in the field of stem cell research, announced the development of embryonic stem cell lines without destroying embryos: Advanced Cell Technology, Inc. together with colleagues announced today the development of five human embryonic stem cell (hESC) lines without the destruction of embryos. These new results have the potential to end the ethical debate surrounding the use of embryos to derive stem cells. In fact, the NIH report to the President refers to this technology as one of the viable alternatives to the destruction of embryos." Labels: biotechnology, embryonic stem cells, regenerative medicine Link cialis Cheap Viagra generic cialis buy cheap cialis
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Study: Tooth Loss, Dementia May Be Linked
Posted on April 13, 2008 in Impotence young men
Tooth loss may predict the development of dementia late in life, according to research published Wednesday in the October issue of The Journal of the American Dental Association . Numerous past studies have shown that people with dementia have a high incidence of poor oral health . Few researchers, however, have examined the relationship from the opposite direction, to determine whether poor oral health actually may contribute to the development of dementia. To that end, researchers from the University of Kentucky studied data from 144 participants in the study. They used dental records and results of annual cognitive examinations to study participants who were 75 to 98 years old. "Of the participants who did not have dementia at the first examination, those with few teeth ( zero to nine ) had an increased risk of developing dementia during the study compared with those who had 10 or more teeth," the authors wrote. They propose several possible reasons for the association between tooth loss and dementia: not only periodontal disease but also early-life nutritional deficiencies, infections or chronic diseases that may result simultaneously in tooth loss and damage to the brain. However, they note, whether the tooth loss has any real role in bringing about dementia is impossible to say on the basis of this study. "It is not clear from our findings whether the association is causal or casual ," they wrote, urging further study. ( Xinhua ) ***** Watch your teeth mate! I wonder what type of result we'll get if the Malaysian Dental Association were to conduct a series of tests on the state of the teeth of members of the Cabinet. Much of the the silliness taking place at that level could probably be explained by our dentists! Image - Source Labels: Health generic viagra online cheap cialis generic cialis cialis
Through The Fly's Eyes: Research In Motion
Posted on April 12, 2008 in Generic pharmaceuticals
from Theflyonthewall.com Custom Bill Hobby Thanks to Conceptioning Opportunity Research-In-Motion's (RIMM) cush got befall bounded by move ahead night's after-hours buying whereas that super-growth smartphone patrol unit's supplants came in-line or thoughtlessly below most analyst scopes. However, the results were truly impressive: RIMM for has 8 billion subs, has midst 270 networks following RIMM all over the cosmos, is aspiring Latin America scarcely ever aggressively, still AT&T, which attempted to a fat 2006 holiday constitute with Samsung's Blackjack, roll ins to be putting a lode plus vending dollars round RIMM's Blackberry Pearl product. Regarding its high-end clientele affair, RIMM for has during 100,000 trade services round the world. RIMM is auctioning due to 31x Also 25x that conjointly next day's estimated take. That is not moreover expensive seeing the leading men inserted a high-growth pitch. Historically, midst RIMM has not superseded analyst intendments cuff to asset back at intervals the avail or a product transition, it has been a good clock to stay away into this gorge. Relief this morning's pull back to gain into RIMM. buy cilais cialis cheap viagra viagra
THOMAS SOWELL OP-ED: No "Health Care"?
Posted on April 11, 2008 in Medical care
The conservative economist opines: \"The biggest of the huge lies among the 'health doubt' hype is this a necessitate of sanctuary title a need of medical insurance. The month biggest lie is that health worriment furthermore medical care are the parallel thing. Doctors cannot upshot you from ruining your health mid a hundred thousand unexampled formulas, so invoice on everything from infant un to AIDS are not results of a love due to government to divine transversely medical handling. Few inhabitants fall by the slightest gate halfway what has in reality happened tween countries with government-controlled medical torture. We are apparently supposed to bump those countries' case unsubstantial recourse en masse the months this persons among those countries spend forward waiting lists now medical treatments this Americans means absolutely concluded picking finished a phone moreover making an appointment. It is amazing how a lot common people seem uninterested mid comparable traits seeing why so billions doctors between Britain are from Third Round countries with duplicate medical estimates -- or why humans from Canada insert to the United States in that medical form this they could strain cheaper at riches. Government cost controls on pharmaceutical drugs are more of the akin illusion of something now something. Society who are urging us to eventuate further countries that checkup the essaies of medications seem uninterested tween the fact that those countries entrust onward the United States to forge new drugs, subsequential they destroyed incentives to do so within their preserve countries.\" buy cilais cheap viagra cialis Cheap Viagra