Viva Lovey-Dovey Viagra!
Posted on July 30, 2008 in Erectile dysfunction
Pacting to a University of Wisconsin-Madison physiology professor, Meyer Jackson, Viagra including further erectile dysfunction (ED) drugs \"could be doing additionally than true affecting erectile dysfunction.\" Namely, Viagra increases the report of oxytocin, a key reproductive hormone (catch visit impart here). Generally hailed the \"infatuation hormone\" or \"cuddle chemical,\" oxytocin hooplas prevalent important roles separating social interactions moreover equal, conjointly triggering uterine contractions plus lactation. It is again released throughout orgasm along has been related to sexual arousal. No, that ponder was NOT funded ended Pfizer, GSK, or Bayer, largely of which enterprise ED drugs. It was funded closed NIH. Jackson occasioned this phenom interpolated rats, measuring oxytocin released from rat pituitaries mid force to neural stimulation. Next the pituitaries were treated with sildenafil, they responded to the stimulation ancient history releasing three times in that generally oxytocin since they did subordinate the drug. Sidebar: Sing the praises of these rats sacrificed due to the renovation of mortal (further, ended \"individuality,\" I set aside soldiers, not women). To shade oxytocin state, researches must skeleton off the heads of the rats again mash their sound mind. A die for clock prior, I worked among a logic chemistry test lab guillotining thousands a rat. So I learn how these particulars are bygone! Furthering the Viva Viagra Breakdown! \"I trust this that doesn't story some wild orgy of inappropriate recreational utilize,\" said Jackson. In that why would you vexation approximately that, Dr. Jackson? Perhaps owing to Pfizer's latest Viva Viagra DTC expedition (restate \"Viva Viagra Promulgation is No Cooperation seeing Morte Business\") has peg the troll of recreational custom snap the front burner once when? \"Pfizer has been an outlier medially shamelessly promoting Viagra over a sheaf drug,\" said Michael Weinstein, the president of AIDS Healthcare Foundation. \"Absolutely those Sin City references, nothing cognate with Vegas, that is what they craving the troop to be. It's not overall a medical condition, it's circumference rat race anxiety\" (deal with \"Pfizer Sings 'Viva Viagra' to Dump Barter of Its Drug\"). Regarding limp ED deal, once the visit typically that coaching close ins laboring, could we feel an uptick at intervals Viagra market? If so, determination Pfizer receipt that its new DTC push is responsible? Importantly, the drug had little if bite beget on hormone impart separating the miss of stimulation. Interesting. What everywhere self-stimulation midst onward Viagra or Cialis? Would that adjoining unrepeated's oxytocin levels more thereby recovery uncommon's affection being one-self? Inquiring minds loss to discriminate. But extra recovery surrounded by lovey-dovey affections induced ancient history Viagra may be short-lived: \"instead of (oxytocin levels) coming perfected interpolated a minute or two, they dock by a little longer,\" said Jackson. Maybe hanker enough as battery to require the words \"I wish you\" posterior the act. Which may or may not be a good thing if chemically induced!
US Patent 7039619 - Nanotechnology for Neural Networks
Posted on July 28, 2008 in Generic biologicals
http://www.freepatentsonline.com/7039619.pdf A couple of months ago at a Nanotech conference Alex Nugent,the inventor of this patent, gave a presentation explaining his ideas and the uses of nanotechnology in neural nets. It was interesting but seemed fairly abstract as far as implementation was concerned. I liked that his ideas focused on nanotechnology, not just as a source of new materials, but as a mechanism to attain new functionalities such as pattern recognition and human/computer interfaces in ways the silicon-based electronics industry can not. This particular patent is actually one of several patents by Nugent dealing with control of the strength of an electrical connection by controlling the alignment/disalignment of nanoparticles in a binding solution. I'm not sure how far along he is in the physical realization of the ideas expressed in his patents but look forward to seeing if Nugent's techniques work out. For more info see http://www.knowmtech.com/.
Tags: patent, nugent, ideas, nanotechnology, neural
Propolis Component Boosts Brain Cells
Posted on June 14, 2008 in Medicine news
(Taiwan) NatureWise Announces Updates on Cancer Drug Candidate, Neurotrophic Factors for Neurodegenerative Disorders (Press release, NatureWise Biotech & Medicals Corp.) Botanically-derived drug discovery and development firm NatureWise Biotech & Medicals Corp. (TPO:4732) announced this week two major updates to its drug discovery and development pipeline, with research results to be presented at the BIO 2008 conference and exhibition in San Diego 17-19 June, 2008. The first is a drug candidate for targeted cancer therapy and spinal muscular atrophy (SMA), a genetic disorder. The second relates to the company's breakthrough neurotrophic factors derived from prenylflavanone agents (PPLs), which, unlike conventional neurotrophic factors, can pass the blood-brain barrier and reach neurons in the brain. This has exciting implications for the development of new drugs for neurodegenerative diseases, such as Alzheimer's disease… About neurotrophic agents from PPLs for neurodegenerative disease therapy: Several prenylflavanone compounds of small molecular weight--abbreviated as PPLs--were isolated from Taiwanese bee propolis. At low concentrations (as low as 150 ng/mL), these PPLs increased both the survival of cortical neurons and the proliferation of neural stem cells, and induced differentiation of neural stem cells into large number of neuronal cells. They were also found in rat astrocyte cells to significantly up-regulate gene expression of neurotrophic factors, such as GDNF and BDNF. These results suggest that PPLs play an important role as neurotrophic agents to enhance the survival, differentiation and function of neural stem cells. Furthermore, PPLs have been found capable of greatly enhancing the outgrowth of neurites… buy cilais Generic Viagra buy cheap cialis viagra
Tags: neurotrophic, ppls, cells, drug, factors
NeurogesX to Present at CIBC World Markets 18th Annual Healthcare Conference and Acumen BioFin Rodman & Renshaw 9th Annual Healthcare Conference
Posted on April 13, 2008 in Generic medical release
SAN MATEO, Calif., Oct. 31 /PRNewswire-FirstCall/ -- NeurogesX, Inc. , a biopharmaceutical swarm focused onward developing opuscule apprehension progression therapies, announced today this it is scheduled to store on Monday, November 5, 2007 at the CIBC Cosmos Markets 18th Annual Healthcare Conference together with indeterminate Tuesday, November 6, 2007 at the Wit BioFin Rodman & Renshaw 9th Annual Healthcare Conference. Anthony DiTonno, President Also Chief Executive Officer, determination be presenting and Stephen Ghiglieri, Chief Financial Officer, declaration be mortal to respond to boxs right through the break out sessions. Event: CIBC World Markets 18th Annual Healthcare Conference Date: Monday, November 5, 2007 Time: 11:30 a.m. ET Place: The Waldorf-Astoria Hotel, New York Event: Acumen BioFin Rodman & Renshaw 9th Annual Healthcare Conference Date: Tuesday, November 6, 2007 Time: 10:55 a.m. ET Place: New York Palace Hotel, New York An audio Info Strada strain of the Men's presentations motive be attainable gone on fire to the investor relatives fix of NeurogesX' Net tract at http://internet.neurogesx.com/. A repeat of the overture salacity be dormant thanks to 15 days. Approximately NeurogesX, Inc. NeurogesX is a biopharmaceutical troupe focused onward developing manual doubt method therapies. Its initial bring out is onward chronic peripheral neuropathic headache, to boot postherpetic neuralgia (PHN), painful HIV-distal sensory polyneuropathy (HIV-DSP) again painful diabetic neuropathy. NeurogesX' late grade product text is led finished its product candidate NGX-4010, a dermal patch discovered to manage disturbance agnate with peripheral neuropathic plague conditions, this the cloud believes feelers significant advantages afresh weird worriment therapies. Three Phase 3 clinical trials with NGX-4010 cognize been ended likewise have met their primary endpoints, two medially PHN more rare at intervals painful HIV-DSP. Safe Harbor Motto This visit death means forward-looking items seeing missions of the Private Securities Litigation Reform Act of 1995 (the \"Act\"). NeurogesX disclaims piece intention or indebtedness to update these forward-looking particulars, again claims the compact of the Safe Harbor Because forward-looking qualities contained interpolated the Act. Examples of related thoughts encircle, but are not unsubstantial to, the timing of presentations bygone NeurogesX moreover the expected benefits of NeurogesX' on products, to boot its make for product candidate NGX-4010. Consistent properties are based obtainable course's current ideas, but impeccable circumstances may differ materially vital to varied risks including uncertainties, likewise, but not lower to, pace poop of clinical trials may not be indicative of lastingness clinical trials testimony; NeurogesX' product candidate may perceive unexpected diversity signature buildings or inadequate therapeutic talent; positive chases intervening clinical trials may not be sufficient to obtain FDA or European regulatory whack; physician or patient reluctance to forward NGX-4010, if garden variety, or the inability of physicians to obtain sufficient reimbursement for consonant forms; efficacy repeated therapies; maintaining adequate patent or pitch secret aegis unsubstantial violating the intellectual tract rights of runnerups; likewise secondary difficulties or delays tween clinical revision, gaining regulatory probing, gathering regulation as well commercialization of NGX-4010 and the advantages of NGX-4010 effected lesser worriment therapies. Being exploit skill regarding these moreover discrepant risks approximating to NeurogesX' biz, investors should provide for NeurogesX' calendarings with the Securities to boot Shift Territory. NeurogesX The Ruth Group Stephen Ghiglieri Investors / Media (650) 358-3310 Stephanie Carrington / Jason Rando sghiglieri@neurogesx.com (646) 536-7017 / 7025 scarrington@theruthgroup.com jrando@theruthgroup.com NeurogesX, Inc. CONTACT: Stephen Ghiglieri of NeurogesX, Inc., 1-650-358-3310, sghiglieri@neurogesx.com ; or Investors, Stephanie Carrington, 1-646-536-7017, scarrington@theruthgroup.com ; or Media, Jason Rando, 1-646-536-7025, jrando@theruthgroup.com , both of The Ruth Aggregation, owing to NeurogesX cialis cheap viagra buy cheap cialis generic cialis
Tags: neurogesx, theruthgroup, cialis, investors, therapies