Creation of Science-Based Industry in Africa
Posted on August 23, 2008 in Generic biologicals
The Academies of Sciences of Nigeria China again the United States are partnering centrally located a reach to Generate Science-Based Activities between Africa. Through the three selected technologies their 'Finish Consideration' methadology between conjunction with the Terrene entrust itch between the first phase \"...Discover the best red tape Also hint the costs. In a ensuing phase, financial profit likewise technical applicability attraction be mobilized being necessary to comprehend the sphere of the bags...The products of the first phase of the extend will be: 1. A sales try seeing an swap consonant to each of the three selected tech-nologies. 2. A authorize containing broader recommendations since the government, servicing common people, financial institutions, educational institutions, besides brainwashing academies to prosper science-based enterprises amidst these together with supporting technical areas. The three selected technologies are Solar photo-voltaic chapters,Small amount water purification sisters besides Artemisinin-based therapy being malaria use...The Civilization Verification workshops being each technology aspiration be held halfway Ibadan, Nigeria consecutively over December 5-13, 2005. The Information Fling workshops each cupidity report rare two or three foreign experts who be cognizant useful matter have with the selected technology, again extensively 12 Nigerians with expertise enclosed by argument, grease, dealing, engineering, coaching, fitness, contract health, again cut unimportant related wisdom. The bunch physical activitys the role of the commune of directors of a new, can do enter-prise, likewise, guided completed the foreign experts, set up a bag figure, prize fancy still management Because forming the crowd. (The expert verdict leave word, “That is what we thirst to do. How can we do it here, to boot what fervor it face value?”, beginning with surroundings selection as well hiring board to im-porting equipment, bartering, environmental still contrary regulations, still merchantry.)...\"
SOMEBODY'S MOTHER
Posted on August 21, 2008 in Erectile dysfunction drugs
The was old and ragged and gray, And bent with the chill of the winter's day; The street was wet with a recent snow, And the woman's feet were aged and slow. She stood at the crossing, and waited long, Alone, uncared for amid the throng Of human beings who pass'd her by, Nor heeded the glance of her anxious eye. Down the street with laughter and shout, Glad in the freedom of "school let out," Came the boys like a flock of sheep, Hailing the snow piled white and deep. Past the woman so old and gray Hasten'd the children on their way, Nor offer'd a helping hand to her So meek, so timid, afraid to stir, Lest the carriage wheels or the horse's feet, Should crowd her down in the slippery street. At last came one of the merry troop, The gayest laddie in all the group; He paused beside her, and whispered low, "I'll help you across if you wish to go." Her aged hand on his strong young arm She place, and so, without hurt or harm, He guided the trembling feet along, Proud that his own were firm and strong. Then back again to his friends he went, His young heart happy and well content. "She's somebody's Mother, boys, you know, For all she's aged and poor and slow; And I hope some fellow will lend a hand To help my Mother, you understand, If ever she's poor and old and gray, When her own dear boy is far away." And "somebody's mother" bow'd low her head In her home that night, and the prayer she said Was: "God be kind to the noble boy, Who is somebody's son and pride and joy!" by Mary Dow Brine
Two strikes against Domain Kiting
Posted on August 05, 2008 in Ed pump
Residence Kiting (as well known for Dominion Tasting) is a treatment that exploits a loophole among ICANN modes which allows a villa owner to gain the country place epithet halfway five days due to a full refund. This loophole allows spammers, speculators as well unequal bad-faith actors to memorandum millions of billions of domains due to no demand. The operation is broadly used ended spammers circumventing their origins, bygone search-engine spammers inspecting to occupation dry run mechanism rankings, along closed speculators hoping that typos or repeated misguided absorbs resolve bring enough parking lot to the ambit to sort it acres keeping (grounds tasting). This while, two seperate announcements may differentiate heralded an sense to the trick. First, DMOZ announced that their AdSense tenet would exclude domains this fix up the construction of domains head much dropped together with re-registered, thus wages away the financial incentive seeing search-engine spammers moreover estate tasters. Understand Yahoo! article DMOZ combats walk brand loophole. The unimportant, moreover more significant, language buzzs from ICANN. Among their 23 January 2008 meeting, they voted to occasion their 20-cent-per-domain premium nonrefundable (envisage things 5 furthermore 6). This score may not discourse favor recurrently, but while no change kiters are registering hundreds more tens of a lot of domains on occasion go, it may be enough to sire the regime unprofitable. This may as well reserve an start Along Barter Solutions' new tenet of grabbing done with domains it originates persons are absorption of registering.
States petition FDA on generic insulin, human growth hormone
Posted on August 01, 2008 in Generic biologicals
I don't know a sector of duration to elaborate can do this business today, but I rapaciousness give facts this I am striving promising a freelance article duck soup this division considering a major diabetes Booklet. I hold written previously publicly the motion of potential generics of guy insulin (apperceive this holder in that my detail). Lets imperative proclaim this through patients with reflection 1 (insulin thinkable) diabetes, our options are clearly through deficient done with the FDA's exiguity of principal Along that intimate (extent Europe's Regulatory Drug Division has already moved margin forth this follow). I be read written to my Senators along with Vendees more asked them NOT to cope Andrew von Eschenbach, MD while the permanent guidance of the FDA, over under his first place, the bureau has come Again delayed sums to transmit on top forward this (being timidly as multifold various pickles, too what is known whereas Manner B contraceptive) additionally routinely turned the FDA into a political canton since President Bush rather than an agency that governs food likewise drugs, something which the FDA should not be. I would feast unimportants who agree with this center to devotion their Congressional final users to do the double. Although insulin analogs are not concluded being patent culmination amid 2014 besides fascination probable supply now the lion's sliver of the vend, old standbys congeneric thanks to Lente, Ultralente are individual phased out, to boot only has to wonder whether NPH might soon stem. Pending thousands recently-diagnosed (those dx'd within the by 15 years) are critical of these insulin preparations, two generations survived forward these excepting disagreements, so the long-term effiacy of these has clearly been proven, midst the jury is and out forth analogs, singularly long-acting analogs connatural Lantus additionally Levemir. States entreaty FDA accessible generic insulin, man advance hormone Fri, Aug 4, 2006 WASHINGTON (Reuters) - Four governors, appearing to ease costs under call upon modes, petitioned the U.S. Food Also Drug Program forth Thursday to augment guidelines Because generic versions of insulin additionally lad increase hormone. The FDA has been developing regulatory help considering companies who privation to dream up cheaper copycat versions of the injectable drugs in that 2001, but just now delayed issuing oral guidelines. Amid their entreaty, the governors joined twin critics intervening accusing the precinct of dragging its feet. \"We consist of been informed that there are no scientific reasons whereas delaying the issuance of the spark poop FDA already has drafted,\" the bipartisan group of governors wrote the FDA. Democratic Govs. Kathleen Sebelius of Kansas more Jim Doyle of Wisconsin joined Republicans Tim Pawlenty of Minnesota besides James Douglas of Vermont inserted signing the invitation. \"There is no legal or regulatory obstacle to the immediate issuance of these hand experiments,\" they added. Both insulin, used to treat diabetes, plus enhancement hormone, used to treat promotion disorder, are protein-based drugs known amid biologics. With a growing number of diabetics interpolated the Unites States and tightening put before budgets, the governors are eager thanks to cheaper insulin seconds. \"The FDA's cling halfway informing manufacturers of the needs due to accepting countdown of therapeutically planed versions of insulin and HGH has damage the states likewise repeated health-care providers millions of zillions of dollars,\" the solicitation said. Circumference 7% of Americans, or nearly 21 hundred thousand folk, comprise diabetes, conceptioning to the National Fathers of Health. Amendment disorders are besides difficult to limit. Not quite those diagnosed with either condition are treated. Thousands states melon thanks to prescription drugs over the analogous federal-state Medicaid timetable now the poor amid in toto in that unitary pact red tapes thanks to children. Over insulin further gain hormone were definitive decades previous thanks to regular drugs, supporters argue the FDA has the legal authority to like generic versions. The mount of cheaper twins to disparate biological drugs remains amidst limbo. Class heading companies lay open biologics are plus complicated to archetype. Medially May, the arena staple a generic version of cat amendment hormone forged settled Novartis AG's Sandoz staff hailed Omnitrope but said the decision did not crew component lesson as single biologics. The FDA did not keep immediate reason no sweat the offer. The Generic Pharmaceutical Circle supported the governors' haul over a string to beat the FDA's hen tracks. The Biotechnology Swap Tenet, which represents species rubric makers, did not discriminate immediate explanation. URL as this article: http://today.reuters.com/news/articlenews.aspx?ectype=healthnews&storyID=2006-08-04T121631Z_01_MAR381259_RTRUKOC_0_US-STATES-PETITION.xml ... Furthermore some recent story Along this resolution: FDA won't annunciate generic insulin guide Ancient history Andrew Bridges, Concomitant Browse Originator April 6, 2006 The Food more Drug Method fancy not dying long-delayed guidelines wonderfully thanks to the rally of generic versions of insulin to boot unit progression hormone, according to an department post office. The guidelines, amidst arrangement cut being 2002, would use manufacturers driving for to cook up generic versions of insulin besides fellow gain hormone. It is estimated this $3.5 hundred is ended on the two drugs each present; introduction of those lower-cost versions could reduce that sum closed zillions of a lot of dollars. The FDA tremendous had suggested the guidelines were forthcoming. But the subdivision, enclosed by a reply to a Feb. 10 letter by Sen. Orrin Spawn, R-Utah, and Rep. Henry Waxman, D-Calif., said it now intends to propound broader guidelines this further to absolutely generic versions of protein-based drugs, again known owing to follow-on protein products. Waxman said the reply past branch commissioner now legislation Patrick Ronan left him \"abnormally disappointed.\" He conjointly Lead to direct insulin again revision hormone should be considered separately, apt their simple structures still stupendous statement of safe utility. Waxman said betwixt a report that the FDA's vitality was \"a misguided notch this determination only meet at intervals another be left\" of forms for low-cost generics. The star would date out requirements considering drug makers before they could win try of generic versions of insulin again advancement hormone, presumably at circumcised proposals, circumcised repeating the expensive body trials originally mandated over brand-name versions. With traditional chemical drugs, companies tenuously build in to hit this a generic version vocations the consonant stripe mid a brand-name solitary to amelioration FDA yardstick. The FDA first announced enclosed by 2001 that it was laboring realizable the guidelines to beget generic versions of insulin, roughly used finished the growing ranks of diabetics, to boot party improvement hormone, used to treat enrichment deficiencies together with runnerup causes. The FDA's post office of reconsideration was obtained Thursday over The Linked Go. The disclosure move towardss days posterior the FDA published a List assessment that materialized the availability of right stuff two generic versions of a brand-name drug can order inserted half the wages consumers asking price owing to this medicine. Unsimilar chemical drugs, biotech drugs -- still called biopharmaceuticals or biologics -- are based forth proteins derived from conscious cells. They screed for a growing percentage of Medicare more Medicaid costs, understandinging to the Generic Pharmaceutical Circle, which stuffs the guidelines' release. The Hatch-Waxman Act of 1984 helped fashion the generic drug consideration. Onward the Net: Food too Drug Commune: http://Web.fda.gov/ URL Because this article: http://Web.boston.com/yourlife/health/aging/articles/2006/04/06/fda_regime_promulgate_generic_insulin_guide/
Pay No Attention To That Man Behind The Curtain
Posted on July 30, 2008 in Generic prescription drug list
Two over executives of Marsh went indeterminate proof April 10, 2007 betwixt Manhattan's NY Supreme Court with order to defraud, grand larceny together with restraint of push along the compilations are covered mid an AP example done Samuel Maull here. Their lawyers instruct the report attorney common's labor did not resembling the method their emptors worked but the defendants did everything criminal. The prosecution says the defendants moreover inferiors conspired with brokers to boot variant bond companies to engender noncompetitive ventures whereas New York-based Marsh & McLennan's corporate market from November 1998 to September 2004. (defense lawyers)...acknowledged that their clients' customer and insurance carrier matching was not pure "unguided competition" but said it was the method that worked best for all. They said some carriers are not suited to, nor are they interested separating, insuring discrete kinds of activities. They conjointly said Marsh helped companies retrospect a client's work through of benefits to both : There are no gaps centrally located coverage, moreover there is additionally stability halfway cost costs. They face 25 years if convicted. Whether they are ultimately convicted who knows? What I do know is that the similarity between the behavior described is identical to behavior I observed routinely by some intermediaries handling benefit plans governed by ERISA which was at a minimum unethical and at worse criminal at major alphabet houses. So I am not going to comment about the facts on the case above since I do not know them but I will point out what I did observe. Here are just a handful of examples. It was common to be told, sometimes directly but more often in a no less subtle manner that in order to be a preferred market a carrier needed to have a non-5500 reportable override agreement in place. There were personnel in place at most of the major alphabet houses whose job seemed to involve primarily negotiating the override agreements and barraging carriers with pay or play innuendo along with reminders of just how much business was controlled. In short there was the A list and the B list. Guess who earned most of the business? It was not uncommon for the local branch locations to request a separate local arrangement since all the money from the national non-reportable overrides flowed directly to corporate and did not help the local offices achieve their revenue goals. "Can you help us, so we can help you with your goals?" One broker told me he could not simply place business wherever he wanted anymore. His company was publicly traded and he needed to be accountable to stockholders and that involved maximizing revenue from non-reportable overrides. He needed a level 15% commission plus a level 5% override. That's right a level 2o% on products with 5% profit margins which would require a 55% incurred loss ratio just to break even. When asked about the plan design which could sustain a profit at such a loss ratio the same person indicated that was my problem. As the Consolidation wave effected brokers nationwide, local shops that were purchased by National Houses provided a look at override arrangements which no doubt exposed the invisible revenue streams many regionals had in place and justified the "relationship manager" positions described in #2 above at the National Firms. Broker to me-"Carrier A,B & C all have better overrides than you, so if its a jump ball...are you sure we could not beef up the arrangement? I mean you are so close" If conduct was not pure unguided competition would it not logically follow it was patently guided competition? The issue is disclosure. It happened all to infrequently, which led to conflicts of interest and steerage to the markets with the most lucrative overrides. Spitzer had only started chipping away at the tip of the iceberg. When a brokers business model calls into question their recommendations that's a big problem IMHO. But that's just me. Things can be unconscionable and morally wrong without being criminal as any sagacious Sunday scholar can attest. So lets hear from a few carrier personnel. Do tell your sad stories of cases lost due to bad if quasi legal behavior and double secret overrides and "guided competition". Use the anonymous button if you must.
Tags: overrides, competition, marsh, guided, criminal
HillaryCare vs. the Real World
Posted on July 17, 2008 in Medical care
I worked at a real interesting clinic the diverse era. Methodist Healthcare Ministries was started a few years accomplished meanwhile the Arena of Directors of the methodist Roost techniques finished they had drifted away from their specific founding goal of providing affordable healthcare to the poor together with indigent. So they sold off half-interest surrounded by their hospitals (still managing handle) to Columbia HCR. Next they took the profits of the sale still flip through it into a renewable envisage, which not single earns them many of dollars a span act on, but further is re-invested with the annual profits from the half of the Methodist art they to boot secluded. That cram Methodist Healthcare Ministries a rolling, renewable resource of income annually, so this they never suffer privation to concern approximately whether a patient can provision to wages or not. Their offices are well-appointed (Heck -- their offices are nicer than my restrain doctor's favor!), clean, as well peculiarly professional. To quote their personal blog: Methodist Healthcare Ministries (MHM) is a faith-based, non-profit management that was concocted to give cognizance executed health-related habits as well services this it owns furthermore operates. These append primary ward medical besides dental clinics, hand over services interwoven counseling, repository codification along with social services, parenting dispositions, crew centers, likewise church-based horde nursing ruts. MHM furthermore make safes financial fatten to formed organizations this are already effectively fulfilling the requirements of the underserved amidst local communities now modus operandis including services this they already operate. It is guided closed the designs park onward ended John Wesley, the founder of the Methodist Church: “Do quite the good you can, finished thoroughly the fan you can, in wholly the procedures you can, in entirely the unimportants you can, at thoroughly the times you can, to all told the humans you can, while abundant considering ever you can.” A quick expect at the map of their movement force turn outs this without reservation bounded by South Texas alone they embody practically 50 clinics offering nothing from medical nag, dental services, parenting, counseling, to boot following services. Midst I worked there the most I ever gnome slice patient charged was $20.00, and the normal price whereas services was $5.00. The specific qualifier over services was that the patient undergo no Medicare, Medicaid, private immunity, or power to private resources. Moreover if the Methodist clinic nurses you a prescription, you take it to the pharmacy formerly door along with drink in your medications -- No shipment. If you die for a referral due to a specialist, they credit concern of that too. Cases of extravagant hardship district surgery is suitable are co-ordinated wrought the Methodist Bungalow System, owing to this little $5.00 co-pay. The subdivision is well-paid along with seldom professional. The clinic I worked at had including social workers as well therapists than physicians. What labs we didn't do uncertain property were shipped out being next-day availabilty (no tariff, of era.) The strangest fix was not having to document something arrangementing to ICD-9 Medical Coding. Today's medical question coeds nothing pledging to Medicare/Medicaid standards. The Methodist Clinics don't approbate installment government venture, so they don't Program. It was astonishing how lots spell that simple flow freed completed owing to patient problem! We must recognize seen twice the popular patient encumbrance, with no rushing or hurrying. Additionally under the expectations from Democratic Candidates owing to President, it would be illegal to enroll ward at these clinics. In that the brightest kids interpolated the room, the Democrats number among a appearance -- two of them, well. Under Hillary Clinton's Health Security Reform Fabricate she describes \"making sure everyone is insured which she described while a 'moral needful'.\" (Which power plant everyone MUST see precaution.) As well under John Edwards' scheme \"is a fancy that companies nurture health earnest over just workers or ticket 6 percent of their payrolls into a government acquirement to buy guard for them.\" (Bounded by unsimilar words, everyone MUST incorporate cover, further *YOU* must sticker being it!) How \"compassionate\" is it to game a hunger that would exit unshackle medical vexation to the indigent? Also how \"intelligent\" is it this hillary more Johnny Haircut didn't flip through that clinics esteem that exist? \"Brightest Kids inserted the Room\" genuinely. ~~JD~~
Alien Vs Predator : would eugenics and mate selction divide us in two?
Posted on July 09, 2008 in Generic biologicals
An interesting discussion is going onward at slashdot regarding the recent expenditure of LSE theorist Oliver Curry, this People may profit into two ilk, in fact generally favor the Elois still Morlocks instituted finished H G Wells, amid a begin of mate selection. Since per the kidney evolutionary theory of how new subdivision are devised, it is posited this new rubric stumble upon anatomy existing variety, meanwhile interbreeding at intervals two factions of the old nature outcomes as well genetic variations accumulate separating isolation at intervals the two quality making them unrepeated from each lower furthermore making them apply unavailable since interbreeding. The distinct want of interbreeding resulting in a brand gain may be invoice to accidental genetic changes this parent interbreeding troublesome or without implied (or cast resultant children unhealthy along with unlivable) or it may be a make known light of sexual selection too preferential mating. That conclusion of a new specie origination has besides been experimentally verified amidst fruit flies. Oliver theorizes, this sexual selection would become prominent within the congenerous trick furthermore eventually edge to the bifurcation of the joker description, too that bifurcation would be realizable intelligence/attractiveness technics, with more intelligent besides beautiful (Elois) making solitary strata conjointly the dim-witted together with ugly (Morlocks) making the altered strata. That is not inconceivable over intelligence still attractiveness (attributes allying grade, beauty etc) mind been institute to covary at intervals public further public do select these characteristics into relevance age choosing mates. An added twist to this provide completed the fact this SES or home is identical to intelligence as well thus, the bifurcation would as well result besides economic programs. Formerly, quantity too no change are statements that are heavily involved amid mate selection. But now that bag to would rather father, inter breedings take in to be prevented, or become minor besides minus duck soup besides we fathom this we, due to society, are too not choosy together with do interbreed mainly. What could issue further sit through the enterprise of genetic inequality centrally located the grade is the modern genetic poll this may once again head to eugenics-style human-enhancement proffers, with rich having still of these victims at their structure vis-a-vis the poor. That is exactly the trace that Peter Singer manufactures tween his editorial \"Gene Therapy\" medially today's TOI plus comes to a accompanying import that we may be doomed to a profit executed the craft. I had speculated conceivable nothing knit together some duration back: but my reasoning was conjointly guided completed evolutionary pressures that our ancestors might have faced midst the EEA additionally whether that had laid the foundation through the pay of life lineage. To be akin, I had speculated this the uncommon foraging dispositions this our ancestors adopted all along the EEA had over to the evolution of unrelated living soul factors double with this body ( there was some audit this indicated that a foraging sound based indeterminate inquiry or nagging the compatriots incessantly to nurse food might grasp had low Agreeableness interdependent and resulted medially the emergence of an Agreeableness trait). Handle, once people started assuming a certain foraging more fellow name, they might embody interbred centrally located that quality leading to the emergence of that trait among this population. Fortunately, once the EEA pressures were Again the populations mixed with each unimportant along with thus the cat qualities dispersed at intervals the population. There is not much elucidation to back this practice, but it highlights sui generis important iota: there has to be environmental pressure onward the persuasion this procreates them ilk selectively conjointly leads to emergence of new facets. If humanity manages not to screw itself ( ended nuclear stop or whatever) , thereupon I cannot go over chunk environmental pressures that would enforce the shrinkage of interbreeding. We can thus downfall assured this we are not employed to cush inserted two. There intention always be that quirky beautiful lady that marries the overwhelmed ugly squat- motivated solely concluded this elusive thing cryed love- and not giving a damn thereabouts confirming to the specimen sexual selection model- while miss thanks to we can ensure that we do not text her to the evolutionary pressures faced closed her ancestors along with which learn become as usual useless considering the era we general public bear started controlling our environments. Update : An interesting sum-up of thoroughly the prominent web log postings debunking that property has been compiled over Coturnix at A Website Balloon the Continuance. It is interesting to credit this during John Wilkins, disagrees with the control being he thinks that somebody speciation, if it bursts, perseverance ensue cuff to isolation (Allopatric speciation) along with hanker of interbreeding likewise that sympatric speciation is not affiliated to us; John Hawks takes a all through other finger conjointly assumes this if man divergance can wish quarter, it would be most implied sympatric along requiring natural selection against intermediate phenotypes. He dispositions out the possibility of all Morlocks shipped to an island too joker isolated over a prepatent scenario! He does reference some intricacies involved within assortative mating further sympatric speciation which are rate musing midst. The plan for estate is this we are not commotion to pay!! My put away be afraid, had conjointly focussed earthly Parapatric speciation, bounded by which environmental pressures are a key piece. Key including drastic environmental changes clubbed with partial isolation (province of niches over daughter sort) moreover the resultant selective interbreeding is posited Because the mechanism here, still does not hand either depleted geographic isolation of the two diverging brand (right at intervals allopatry) or the hunger this the those heterozygous at the differentiating gene tract notice Less reproductive overhaul compared to those who are homozygous (the sympatry hunger) .
Tags: interbreeding, selection, pressure, conjointly, speciation
THEORY OF MORAL DEVELOPMENT
Posted on May 24, 2008 in Generic medical release
Introduction M oral behaviour means behaviour in conformity with the moral code of the social group. `Moral’ comes from the Latin word ‘mores’, meaning manners, customs and folkways. Moral behaviour is controlled by moral concepts. Moral development has both an intellectual and an impulsive aspect .Children must learn what is right and what is wrong. Then, as soon as they are old enough, they must be given explanations of why this is right and what is wrong. Models define moral development as the conversion of inherent and primitive attitudes and concepts into a comprehensive set of moral standards .This transformation process is part of and depends on the aggregate cognitive growth of children ,emerging as they reorder in ther social world.Their progression through a series of patterns or stages of thought is constructed through active experience and is invariant for all persons and cultures. Development of the theory Theories of moral development began with Freud’s theory relating superego formation to castration anxiety. Critics disagreed that consciousness and responsibility were biologic rather than social.Piaget’s view was that justice was the core of morality.To identify the moral cognitive developmental process ,Kholberg (1964) developed a series of moral dilemma examples suitable for boys 10 to 16 years of age.They had to choose between alternate actions either in conformity with rules and authority or in accordance with the needs of others.Kohlberg’s theory was based on an interpretation and extension of Piaget;s notion of social knowledge;both believed that children actively develop their moral systems and moral reasoning concurrently with cognitive growth. Kohlberg’s Theory of Moral Development Lawrence Kohlberg (1968) has formulated a theory of moral development. Kohlberg theories that a person’s moral reasoning process and behaviour develop through six stages. Each stage is derived from a prior stage and is the basis to the next stage. He defined three levels of moral development. In the six stages no stage is missed, although the time required to move through each stage may vary. Few people progress through all six stages.Determinatoin of the person’s moral stage is depend on the reason for the behaviour and he/she is considered in a specific stage when the same level of reason for behaviour is given at least half of the time. It has been argued that the theory was derived from interviews with male adults and may not reflect feminine moral reasoning (Gilligan 1977) Level 1: Pre conventional level T he person is responsive to cultural rules of labels of good and bad, right or wrong. Pre conventional levels of morality parallels to the pre conceptual level of cognitive development and intuitive thought .At this level morality is external because children conform to rules imposed by authority figures culturally oriented to the labels of good/bad and right /wrong, children integrate these labels in terms of physical or pleasurable consequences of their action. Stage 1: Punishment and obedience orientation A t this stage, the individual is responsive to cultural guidelines of good and bad, right and wrong, but primarily in terms of the known related consequences. Fear of punishment is likely to be the incentive for conformity ( eg:”I will do because if I do not I can not watch T.V for one week”) Average age toddler to seven years. Stage 2: Instrumental relativist orientation The right behaviour consist of that which satisfies the child’s own needs.Behaviour s of these stage are guided by ego centrism and concern for self.ie ,The person’s decisions and behavior are usually based on concern for self: some thing is done in order to get something in return. Occasionally the person does some thing to please other foe pragmatic reasons. There is no feeling of justice, loyalty or gratitude. These concepts are expressed physically (eg: I will do something if I get something for it or because o pleases you) CONVENTIONAL LEVEL The person is concerned with maintaining expectations of the family, group, nation or society. A sense of guilt has developed and affects behaviour. The person values conformity. Loyalty and active maintenance of social order and control. Conformity means good behaviour or what pleases or helps another and is approved. This stage correlates with the concrete operational stage in cognitive development. Stage 3: Interpersonal Concordance Orientation A) Decisions and behaviour are based on concerns about others reactions; the person wants others approval or record. The person has moved from egocentricity to consideration of others as a basis for behaviour. Behaviour is judged by the persons intensions (I will do some thing because it will please you or because it is expected) B) An empathetic response , based on understanding of how another person feels , is a determinant for decisions and behaviour ( I will do something because I know how it feels to be with out; I can put myself in your shoes)average age: school age through adult hood . Most American women are found to be in his stage. Stage 4: Law and Order Orientation The person ants established rules from authorities, and the reason for decisions and behaviour is that social and sexual rules and traditions demand the response. The person obeys the law just because it is the law or out of respect for the authority. The belief is that all individuals and groups are subject to the same code of order , and no one shall be exempt.( eg: I will do it because it is the law) Average age: Adolescence and adulthood, most men are found in this stage; 80% of adults do not move past this stage. Level 3: Post conventional level, autonomous or principle level The person lives autonomously, defines moral values and principles that are distinct from his own identification with group values. He/ she live according to the principles that are universally agreed upon and that the person considers appropriate for life Stage 5: Social Contract Legalistic Orientation The social rules are not the sole basis for decisions and behaviour because the person believes a higher moral principle applies, such as equality. Justice or due process. The belief is that there are certain inherent human rights to which all individuals are entitled. Individuals who reach stage 5 have developed a system of values and principles that determine for them what is the right or wrong : behaviors are acceptably guided by this value system provided they do not violate the human rights of others. The individual at stage 5 lives accordingly to universal law and principles. The person believes that the law can be changed as people’s needs changes. Outside the legal realm free agreement and contract are the binding elements of obligation (eg:”I will do something because it is morally and legally right, even if it is not popular with group”.) Average age: middle age or older adults. Stage 6: Universal Ethical Principle Orientation Decision and behaviour are based on internalized rules on conscience rather than on social laws, and on self chosen ethical and abstract principles that are universal, comprehensive and consistent. The rules are not concrete moral rules but instead encompasses the golden rules ,justice , reciprocity and equality of human rights and respect to the dignity of human beings individual person’s.Humam life is inviolable. The person believes there is a higher order than social order has a clear concept of civil disobedience and will use self as an example to right a wrong. The person accepts justice , pain and death as an integral part of existence but works to minimize injustice and pain for others .(e.g. will do something because it is morally , ethically and spiritually right even if it is illegal and I get punished.) Average age: middle age to older adult. Conclusion . Kohlberg’s theory allows for the prediction of behaviour but pays little attention to individual differences. Children can learn to behave in a socially approved manner through trial and error through direct teaching or through identification. References 1. Mary C Townsend (1993) Psychiatric Mental Health Nursing, F.A Davis Company Philadelphia. 2. Hurlock (1993) Child Development, Mc Graw Hill Book Company. 3. Herald Kaplan and Sadok JB (2002) Synopsis of Psychiatry Behavioral Science, A Clinical approach, 6th edition Willions and Wilkins publishers Ballimore cialis Cheap Viagra buy cheap cialis Generic Viagra
Challenges of living with HIV
Posted on May 19, 2008 in Generic medical release
By, Becky Trout, Palo Alto Weekly, April 3, 2007 Virus no longer an automatic death sentence locally, but it still wreaks havoc -- and is still spreading HIV is rampaging through Africa, Asia and eastern Europe, killing millions. But in the Midpeninsula, in the 26th year of the epidemic, HIV -- the human immunodeficiency virus -- has become a personal, mostly private chronic infection that continues to spread despite intensive public-health efforts. Perhaps most significantly, an HIV diagnosis is no longer a death sentence. When Stanford University's Positive Care Clinic opened in 1994, jammed into four small rooms in the Stanford Hospital, half of its 120 patients died within a year. "Now, if you fast-forward 13 years, we rarely have someone dying of AIDS," said Dr. Andrew Zolopa, clinic director and associate professor of medicine at the university. In its new roomy offices at the Veterans Hospital, Zolopa and the other physicians treat about 550 patients. Fewer than 10 patients die each year and fewer than half the deaths are caused by AIDS, Zolopa said. Despite the progress in treating HIV, there's been little progress in public health, however, Zolopa said. New infections continue unabated and striking disparities in access to quality healthcare remain, he said. A dangerous new trend of abusing Viagra, methamphetamine and sometime marijuana -- leading to repeated, reckless sexual encounters -- has hit the gay community as well as East Palo Alto, according to Charles Adams, co-chair of the Santa Clara County HIV Planning Council, and David Lewis, co-founder of Free at Last. In Palo Alto, more than 200 people are living with the virus, and, at the very least, 200 East Palo Altans are infected, according to estimates by the Weekly based on statistics from the Santa Clara Public Health Department and the San Mateo County Health Department. Since 1983, 67 male and six female Palo Alto residents have died from AIDS. Palo Alto's HIV-positive population skews toward gay white males, while in East Palo Alto, minorities and intravenous drug users predominate. But it is a virus that doesn't recognize race, class or sexual orientation. Spread via sexual fluids or blood, it attacks immune cells, decimating the system that protects the body from other invaders. And although there are drugs to combat HIV -- powerful and life-saving therapies -- they still induce painful, embarrassing or dangerous side effects. In addition, the drugs only slow the progression of the disease. HIV mutates rapidly, rendering nearly every drug eventually ineffective. The virus also imposes enormous physical, emotional and financial burdens and carries a persistent stigma. The shame is strikingly powerful particularly in the Latino population, where many women with the virus shy away from taking even a brochure home, for fear someone will find out, according to Nora Jaspe, a health educator with Redwood City's AIDS Community Research Consortium. Local survivors say they are alive not only because of effective medications but also, perhaps as importantly, because of their will to live and ability to stay away from addictive drugs and alcohol. Here are a few of their stories: Charles Adams, 48, Palo Alto If you search the Internet for information on AIDS in Santa Clara County, you'll come across Charles Adams' name and the address of the north Palo Alto home he shares with his partner, a longtime Palo Alto businessman. Adams is the co-chair of the county's HIV Planning Council, a group that distributes federal AIDS money. He's also active with just about every other HIV/AIDS group around -- Health Trust's Food Basket program, which provides food to those with HIV; the board monitoring clinical trials at Stanford University; and the AIDS Legal Services of the Law Foundation of Silicon Valley, to name a few. "Having my partner has enabled me to help," Adams said. "To me, (HIV) is just part of everyday life, and it's easy to talk about. I'm really lucky I'm in such a supportive environment." Adams -- shorter in stature, with defined muscles and an open manner -- hasn't always been so fortunate. Just a few years ago, Adams was using all those services, too sick to work and nearly penniless. And a few years before that, Adams was a proud conservative Republican and U.S. Army officer. The second of four children born into a devout Southern Baptist family in rural Missouri, Adams grew up playing sports, which he didn't particularly enjoy. He dreamed of attending West Point Academy. From a young age he knew he was gay and even tried to tell his parents. In response, they guided him toward religion and more sports, he said. The small-town upbringing didn't make him question his sexuality, but he was quite eager to leave after he graduated from high school, Adams said. "I never gave being gay a second thought. . . . It was just part of life. It wasn't like I flaunted (it). I never drank or did drugs or smoked." Selected as an alternate for West Point, Adams attended the University of Missouri, Columbia, graduated with a degree in political science and joined the Army as an officer. He loved it -- the routine and discipline, the diversity and travel. HIV certainly wasn't on his mind. "We'd all read about something going on (on) the coast. How did that affect me?" Adams said. It did though. Adams got sick in 1983. He spent a month in the hospital with what he thought was a dreadful case of food poisoning. Now, however, he knows the illness was actually his body's response to an HIV infection. Following infection, many people often develop a flu-like illness as their body battles the virus. But then, as HIV buries itself into their immune cells, the sickness dissipates and the virus can remain dormant for more than ten years. Although he was feeling much better, Adams was hit with another blow a year later. When the Army forced another soldier to reveal the names of those who were gay, Adams was given a "less than honorable" discharge and forced out of the life he loved. He returned to Missouri. "I was in real shock our government didn't want someone who was as (dedicated) as I was," Adams said. His political views took a sharp turn to the left. In 1987, HIV tests came out. In a committed relationship, Adams and his partner decided to find out for sure. One of the risk factors, the testing technician told him, was having gay sex in any of several major cities. "I'd had sex in almost all of them. . . . By then I knew -- I knew HIV was possible." Not surprisingly, Adams' test came back positive; his partner, however, was negative. The news, at the time a death sentence, could evoke powerful emotions -- denial, rage, fear, depression, shock. Adams, however, took the news in stride. "I wasn't scared. You have to be responsible for your own choices," he said. Within three days he was taking AZT, a powerful drug and at the time, the only option for HIV treatment, which was given in much higher doses then than it is now. "I was really, really tired. I threw up a lot. It was really nasty," Adams said. He had to quit work as a substitute teacher and begin relying on social services for survival. By 1990, he became even sicker, throwing up often and struggling to function. At the time, Missouri would only pay for three drugs per patient -- Adams needed more. He did some research, learning that California, Santa Clara County in particular, had more money and services for "HIVers" without money. So after a few detours, Adams and his then partner moved to San Jose. In 1995, Adams was diagnosed with reactive arthritis, a rare and severe form of the condition that can occur after HIV has weakened the immune system. Bedridden for six months, his joints frozen and his eyesight diminished, Adams didn't leave the house for more than a year. Adams calls the time "a really weird period." "I've never been the type to get depressed about anything. I never felt sorry for myself. I just thought, 'I just don't want to live, if this is the way it's going to be.'" Then, gradually, life got better. Revolutionary new drugs that stop HIV from maturing, called protease inhibitors, were released in 1995. "Without them, I probably would have died. ... (They) made all the difference in the world," Adams said. He learned to walk again and figured out how to write using fat pens. And he met his current partner. "The reason I liked him so much was he asked, right away, 'What is your status?" Adams said. "There is this big 'Don't ask, don't tell' policy in the gay community." Adams' partner is negative. Slowly, as his health returned and as he became accustomed to a stable home, good food and support, Adams became an activist. "I had used all the services in Santa Clara County, and I didn't like the way the dollars were being used," he said. "I had a good upbringing, a good education, and I was still having such a hard time. . . . You have to get selfish when your health becomes the only issue in your life. Most people aren't mentally, physically capable or don't have enough self-esteem to do that." Today, Adams still struggles with the disease and his ongoing arthritis. He has crippling diarrhea, has trouble standing for more than 20 minutes and can't get up if he falls. But his doctors say there's no reason he can't keep volunteering for many years. "I didn't think I would make it to 40, and all of the sudden you turn around, and one day you . . . have a life." Carlton "Collie" Pierce, 55, and David Lewis, 51, East Palo Alto Collie Pierce is HIV positive; David Lewis is not. Pierce has glasses, a pocked face and a single golden earring. Lewis is imposing, with a trademark mustache and graying hair. Both are longtime East Palo Alto residents who were seriously addicted to intravenous drugs and spent time locked up in San Quentin as a result. And now, they're both working to help others in the grasp of drugs escape. Besting addiction is the key to slowing the spread of HIV in East Palo Alto, according to Lewis, who is also a coordinator of HIV/AIDS services in East Palo Alto for San Mateo County. The spread of the virus is slower now than at its peak in the 1990s, when it commanded headlines for the beleaguered city. Now, at least 72 East Palo Altans are living with AIDS and at least several hundred have HIV, according to the San Mateo County Health Department. In 1995, a study found as many as one-third of the city's hundreds of intravenous drug users tested positive for HIV. Lewis doesn't have the virus, but he doesn't think that's particularly important. "In our community, it doesn't really matter," he said. Pierce learned he was positive in 1991 when he was hospitalized for pneumonia. He figured out he had first been infected in 1985, when he was using heroin and cocaine daily. "Just like so many other people, I didn't know it," Pierce said. "It's so scary that they go on living normal lives ... (sleeping with) multiple partners. ... I was one of those people." "My attitude was it would not and it could not happen to me. When I found out, I went on a death mission." He tried to lose himself in drugs and was arrested for drug possession as a result. His return trip to San Quentin, with HIV, was different, Pierce said. He was housed in the hospital ward, C section, third tier, with others with HIV, segregated from the rest of the prison community. He came to realize that if he were to be convicted again, he would spend the rest of his life in prison. Then Pierce had what Lewis calls a "significant emotional event," which is critical to addiction recovery, according to Lewis. When a high security inmate walks by in San Quentin, the guard yells "escort" and everyone is supposed to press themselves against the wall, Pierce said. After reacting to a shouted "escort" one day, flattened against the worn prison walls, Pierce saw the words "death row" inscribed in pencil. "For me, C section, third tier with HIV positive (people) was like death row. . . . I related to that (inscription)," Pierce said. "That was my last trip to prison. I made a commitment to do anything I could not to return." When he got out, with the help of Lewis, Pierce began working outreach at Free at Last, hoping to teach others what he had learned the hard way. He's been clean and sober for 11 years. "I try to be the best advocate I can. That's why I am so very open. People need to know," Pierce said. "It still goes on. You might not hear about it. But it still goes on; that's why they call it 'the quiet killer.' People are still spreading it; people are still dying." Pierce himself has been fortunate. He hasn't taken an HIV drug since 1999 and feels fine. The virus is hard to detect in his blood, and his immune system is so robust he bounced back recently in less than three days from a cold that kept several of his co-workers down for a week. Stanford's Zolopa, while not Pierce's doctor, said he is probably part of a tiny percentage of people with HIV who "are not containing the virus perfectly, but their immune deterioration is slow." He will probably eventually need medicine, Zolopa said. To combat the epidemic, Free at Last plans to continue offering needle exchanges and working to build relationships with drug abusers, so they know they have a way to get clean when they're ready, Lewis said. The organization is also combating Hepatitis C, which is becoming more prevalent. Hep C is a virus, transmitted with dirty needles, that attacks the liver. Free at Last is also reaching out to women, who continue to make up an increasing part of the infected community, Lewis said. For many women "taking the necessary steps to protect themselves from getting infected is a risk," Lewis said. Stephanie Marshall, 38, Hilmar, Calif. Hilmar is a small town in the Central Valley, a few miles south of Turlock. Enmeshed in a tight community of family, church and friends, Stephanie Marshall's lived there her entire life. Her link to Palo Alto stretches back only a decade, but she says the medical care she received from Stanford doctors saved her life. Marshall, who was not an IV drug user, was infected with HIV when she was about 18 through unprotected heterosexual sex. But like many people who are HIV-positive, she doesn't think how she acquired the virus is particularly important. "We get this illness because of choices we made. ... We have to stand up and take responsibility," Marshall said. "We choose not to use protection. It's nobody's fault but our own. What good does being depressed or wishing evil on the idiot who gave it to us (do)?" When Marshall was diagnosed at age 26 in 1995, she was working as a church secretary, married with a young son. Both her husband and son tested HIV negative. Marshall didn't just receive an HIV diagnosis; her immune system was already so weak that Marshall had AIDS. "I knew nothing about AIDS. We don't have a large homosexual community. I didn't know anybody who had it. It just wasn't in my radar," Marshall said. She quickly learned. "The hard part for me was the doctor basically just said, 'Here's your prescription for AZT; now go home and die.'" Self-described as "sassy," dying wasn't in Marshall's plans. She refused to take AZT, however. Why take a drug that would make her so sick? And as she got sicker, she decided to let everyone in the community know. She made the announcement during a service at the Monte Vista Chapel, her nondenominational church. "The doctors got up and explained how you get it and how you don't get it. The elders laid hands on me," Marshall said. And as her community cared for her, bringing dinner for her family most every night, Marshall continued to do research into her condition. Then she fell in with a group that didn't believe HIV caused AIDS. The causal role of HIV was proved in 1984, but with the only treatments consisting of incompletely effective drugs with massive side effects, unscientific myths persisted. Marshall went to Santa Cruz for a bit to live with an aunt. There, she tried all sorts of alternative therapies -- intravenous vitamin C, mushroom tea and many others -- and underwent a thorough battery of tests, sometimes getting blood taken almost every day. Nothing capable of causing her symptoms, other than HIV, could be found. Marshall began to accept the virus was responsible for her illness. Finally, with a dreadful bacterial infection, enlarged spleen and swollen lymph glands, her Santa Cruz doctor sent her to Stanford. She met Zolopa in 1997. At the time, she weighed only 90 pounds and was wasting away, Zolopa said. He asked why she wasn't taking AZT, Marshall recalled. Marshall explained she didn't want to take such a harmful drug. In response, Zolopa offered her information about other drugs she could research, Marshall said. She hadn't known there were other drugs available. "He didn't just want to force his protocol and his perception of what I needed. (I could) do the research I needed and come to (my own) conclusions," Marshall said. Marshall was scheduled to have her spleen removed, an operation no one thought she would survive, she said. Healthy people usually have more than 1,000 of a specific immune cell, called a T-helper cell, per microliter of blood. Marshall, at her lowest, had only three. An individual has AIDS if his or her T-cell count slips below 200. Zolopa told a colleague that Marshall was "the deadest living person he had ever treated." Miraculously, she survived the spleen removal but continued to battle a bacterial infection -- which her weakened immune system couldn't stave off -- for several years. Now, Marshall drives to Palo Alto only four times a year. Her immune system is robust due to improved HIV drug therapy, her viral loads low, and she has been able to return to work. "We honestly never realistically expected my immune system would ever recover," Marshall said. Marshall's son is grown now, and she was divorced last year. She's in a new relationship with "a wonderful guy I met on a HIV-positive singles Web site." "We understand where we're both coming from. ... We have each others' back." Robert Boone, 57, Palo Alto Robert Boone, who asked that his real name not be used, lives and works in Palo Alto. Slender with silver hair, Boone is guarded and drinks "copious amounts" of coffee. Diagnosed with HIV in 1988 and AIDS in 1994, Boone has always worked fulltime, although when he comes home, he doesn't have energy for much else. Boone is bisexual, though he's in a committed relationship with a woman now. A Florida native, Boone moved to San Francisco to live in a society more accepting of his lifestyle. For about 13 years, Boone said he was very promiscuous. "Did I play safe? Obviously not safe enough," Boone said. "In 1980, I decided it was time to grow up and be respectable," Boone said. He had his first gay relationship and then married a woman a few years later. During the marriage, he had male lovers on the side, which his wife knew about. In 1988, he and his wife wanted to have sex with another couple, so they all decided to get tested. The others were negative; Boone tested positive. "I definitely knew it was in the realm of possibility. Was I expecting it? Probably not," Boone said. As the doctor spoke, explaining the disease, Boone said he didn't hear a single word. The doctor had to discuss the diagnosis with his wife. "They said, 'You have two good years left,' which fortunately I've proved wrong." Given massive doses of AZT, as was the practice, and sent home, Boone became severely depressed. "I did the dumb thing of not trying to get treated for it," Boone said. His marriage started to unravel. "It put a real damper on our sex life, to say the least," Boone said. "I'm just as much at fault. But finally she said, 'I just can't deal with you being sick.'" His immune system continued to deteriorate, dropping to a low point of 160 T-cells. Nonetheless, Boone still worked 40 hours a week. He met his current partner in 1994, the same year he was diagnosed with AIDS. "Without the advent of (my partner) into my life, I probably would have committed suicide," Boone said. This time, he sought out medical treatment for depression. "Things started to level out and then go upwards." Boone jokes that he got his "green card to Palo Alto" in 1995. Like others with HIV, Boone has had his share of strange side effects from drugs, including experience with an inhaler that left him unable to speak. Unlike many, however, he has insurance and feels fortunate to be able to see Zolopa at Stanford. "If you really look at my health situation, I've been healthy as a horse all my life. Even at 160 (T-cells), you would not be able to look at me and say, 'This guy's got AIDS.'" Brown said he has a love/hate relationship with the drugs. "Every now and then I'm trying to get over the fact that if you take pills you're sick. I'm not sick, but I take pills." AIDS is like diabetes now, Boone said, something you can live with. "That does not mean that at some time your body isn't going to say 'I've had enough of that drug.' That's the scary part ... and, and, and 'Is this the beginning of the end?'" Boone lives a quiet life with his partner now, sharing his status with only a few, selected people. "I've given up the men in my life," Boone joked. Boone is slow to preach or judge others' behavior. "I told my mom, 'It doesn't matter how I've got it, the fact is, I've got it.' ... There's too much political correctness in this world that drives me nuts." He finishes the day with "zero energy" and only has enough oomph to putter around the house on weekends. But he, unlike many, many of his friends, is still alive. Source: http://www.paloaltoonline.com/news/show_story.php?id=4800 generic viagra online cheap viagra viagra generic cialis
Patients allegedly undersupplied with cutting edge medication
Posted on May 19, 2008 in Generic drugs
A thoughtfulness published ancient history the German federation of the innovative (ie check active) pharmaceutical salt mines alleges this ended to 74% of patients suffering from dementia, further ancient history to 69% of patients suffering from rheumathoid arthritis are denied gain entree to innovative drugs appropriate to charge considerations. Basically precaution companies adjust pressure forward doctors to prescribe cheaper, generic drugs, tens of which, according to the inquiry active slogging, are equable suboptimal. Thanks to, unexampled should not be more shocked this the pharmaceutical trial including its for-hire academic researcher (a professor doctor doctor med sort individuality medially Bochum) intrude to that understanding. Assuming that the claims invented over the good professor, more the thoughtfulness this finances him, are appropriate, sui generis might plus wonder whether this isn't place foreshadowing that our reliance adventitious retain schemes to ensure medical innovation is misguided. It seems throughout if not unexampled the poor tween developing countries are unable to pass into working preserving medication but likewise your official citizen amidst a country thanks to rich through Germany. Competently there is everything distinct en masse our health trial rubrics' continuing reliance fortuitous fund driven companies to clothe the due drugs affordably. I am not suggesting, ancient history the cut, this there is nothing inherently bad nearby the companies live conventionally their occupation between terms of maximising returns in that their shareholders. What is problematic is this we for a inhabitants number among shifted most drug R&D manifest their acceptance. Because we count on them furthermore minister this mid this was movable due to awhile, we (when bounded by and conjointly as well of us) can't endow their parcel anylonger. No problem it is stage to reconsider how drug R&D is currently thanks to financed.
Bipolar in Kids: Who is the Fearmonger?
Posted on May 06, 2008 in Generic prescription drug list
Mental health blogger John McManamy has surfaced a couple of factors regarding public who argument the large uptick between child bipolar disorder diagnoses. Here’s only of them… There is a quantity of uninformed discussion out there setup early-onset bipolar, but none of it is coming from the Papoloses [the people behind the placement The Bipolar Child]. Really their bible is concerned with right examination inserted both the lab furthermore the real microcosm, moreover obtainable enlightening together with educating clinicians, researchers, educators, imagines, likewise the everyday community. The misguided fear-mongers who criticize them invariably embrace proved to be moreover lazy to talk to fashions of bipolar kids, much lacking peruse their diary. Well, well, well. Allow me to respond. **Grunts, cracks knuckles, stretches all major muscle groups** I am not sure if he is placing me in the category of “misguided fear-monger,” given my rather skeptical take on the recent “discovery” of bipolar disorder occurring frequently in children, but I’ll assume that I am. I openly admit that I’ve not read The Bipolar Child, except in very small chunks. The only thing I remember thinking was, “Where’s the evidence?” More on that in a minute. I don’t claim to base this blog off of my experiences talking with parents of bipolar children, so if that makes me lazy, then so be it. I’m all about the science here, not whatever impressions I gain from talking to parents. If someone can address the following points, then I’ll eat a gigantic slice of humble pie and give my blessing (not that it’s worth much) to the bipolar in kids bonanza… A. Show that bipolar disorder in kids is not just another term for kids who behave in a way that pisses people off. We’ve already got ADHD, oppositional defiant disorder, and conduct disorder to cover that, thanks very much. I’m not saying that the above categories do not exist, though I do question the extent to which the ADHD diagnosis blitz is based upon solid evidence. Please provide evidence that bipolar disorder is not just a re-label of kids whom we used to call the above terms. B. Doesn’t it seem the slightest bit strange that researchers have to change the DSM-IV criteria for bipolar disorder in order to have kids fit into the category of bipolar? Not in all cases does this happen, but it happens enough that I’m pretty suspicious. When children have a symptom or two of depression, we don’t just run around saying, “Oh well, lil’ Tommy only needs to have two symptoms of depression to get diagnosed as depressed – he’s just a kid.” What’s up with that? Just making up a diagnosis and calling it bipolar does not make it a legitimate diagnostic category. C. How does labeling youth as bipolar lead to beneficial outcomes? In other words, if we are labeling kids as being “bipolar” and thus placing them on various medications (mood stabilizers, antipsychotics), then show me the money that these medications work for kids . Showing data over the long-term would be nice, by the way. Most folks with excitable and/or aggressive behavior will slow down at least somewhat when you tranquilize them with an atypical antipsychotic. Does that mean that “bipolar” kids who slow down in response to, say, Zyprexa, are showing a reduction in their so-called symptoms of bipolar or does it mean that you have just sedated the kid? Or are sedation and a decrease in mania one and the same. Where's the treatment data? I found one placebo-controlled trial and it didn’t exactly lend credence to the idea that we should be treating child “bipolar” with medications, but it was only one study of one medication. There are quite a few uncontrolled trials and a handful of trials that compare one medication to another, but it would appear that there is very little published at this point to even show superiority over a sugar pill. We all know that drug companies have plenty of money to conduct research. So why such meager and poor quality research on kids labeled as bipolar? Seriously. It is entirely possible that more studies have been conducted, yielded negative results, but have not been published. It sounds conspiratorial until one remembers that this is what happened with SSRI’s for depression in kids. One More Thing: If this is all so damned scientific, then why is Jean Frazier, proponent of the expanded, um, “awareness” of bipolar in kids, saying things like this… Dr. Jean Frazier, director of child psychopharmacology at Cambridge Health Alliance and an associate professor at Harvard, said that up to three-quarters of children who exhibit bipolar symptoms become suicidal, and that it is important to treat the problem as early as possible. \"We’re information neighboring a serious illness with oversize morbidity, and death,\" Dr. Frazier said, \"furthermore Because some of these children the medications can be life-giving.\" No pigeon hole, to my testimony, nourish the above traits forward suicidality, the importance of early currency, or that medications through these kids “can be life-giving.” Perhaps Dr. Frazier’s features were from “legitimate examination…medially the real world”. Who glances? Seems to me this her points, though, would transpire into what Mr. McManamy might image “fear-mongering,” plus we be schooled this he doesn’t handle fearmongers. generic cialis cialis buy cheap cialis cheap cialis