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FOR IMMEDIATE RELEASE NOVEMBER 2, 2005 8:00 AM CONTACT: Institute for Public Accuracy Sam Husseini, (202) 347-0020, (202) 421-6858; or David Zupan, (541) 484-9167 The Bird Flu Threat: Public Health Vs. Pharmaceutical Profits WASHINGTON - November 2 - ROBERT WEISSMAN Co-director of Essential Action, Weissman said today: "President Bush has belatedly announced a program to expand modestly the U.S. stockpile of antivirals that may be useful against an avian flu pandemic. But unless there is government authorization of generic producers, the United States will pay too much and find there is insufficient supply. Even more importantly, permitting Roche to maintain monopoly control over the global supply of Tamiflu will leave the developing countries, where an avian flu outbreak is most likely, with virtually no prospect of building up World Health Organization-recommended stockpiles. Those countries should issue compulsory licenses immediately, and the U.S. should give its blessing." Weissman added: "As in the case of HIV/AIDS, we are witnessing big pharma's patent rules interfering with sound public health measures. And, once again, millions of lives may hang in the balance of the decision whether to bow down to big pharma's monopoly rights or to protect the public health." More Information Dr. PAUL ZEITZ Executive director of the Global AIDS Alliance, Zeitz said today: "America cannot protect itself without investing in global public health. ... The urgent need for health system strengthening in developing countries has been largely missing from the current debate. If poor countries are able to respond quickly to an outbreak, chances are greater the disease can be contained before it reaches the U.S. ... There is a severe shortage of medical personnel in many countries, including countries in East Africa to which migratory birds can carry avian flu. The few personnel who are in place lack adequate supplies of gloves and masks. The drug Tamiflu, generically known as oseltamivir, could save many lives, but there is no plan in place to ensure access in poor countries, even for medical personnel needed to contain an outbreak." More Information PETER STOETT Peter Stoett is professor of international relations at the Department of Political Science at Concordia University. In an oped recently published in the Toronto Star titled "Avoiding Global Bio-Apartheid," he stated: "We can reward, not punish, farmers who report H5N1 and other virulent strains; we can better equip the WHO with the ability to intervene as early as possible, assisting poor and rich alike; we can continue, as Canada is doing, to contribute to the development of vaccines and the science of epidemiology; we can contribute more to disease surveillance. ... Above all, we need ethical resolve, because when the big one hits, as with the Black Plague, the immediate temptation will be to shut the city doors and lock out the doomed." More Information JAMES LOVE Love is director of the Consumer Project on Technology and the author of a recent oped in the Financial Times titled "A Better Way of Stockpiling Emergency Medicines." Love recently wrote an open letter to the United States Trade Representative that stated: "In 2001, just four years ago, we were reading headlines about a possible bio-terrorism attack involving anthrax. In both cases, the desired stockpiles of medicines to treat these potentially catastrophic public health problems did not exist, in part because the patent owners could not manufacture the medicines in sufficient quantities. "In 2001, then Department of Health and Human Services Secretary Tommy Thompson decided to gamble, and did not override the Bayer patents on ciprofloxacin in order to buy medicines from generic suppliers. As a consequence, the U.S. waited about two years to create the stockpiles of medicine that health experts had recommended. Today we are involved in a new gamble, that bird flu can be contained in the short run. Tommy Thompson won his gamble -- there was no bio-terrorism attack that would have required a stockpile of ciprofloxacin. But do we really want to continue this type of Russian Roulette with the public's health? ... The big pharma lobby has elevated the ideology of the exclusive rights of the patent very high, putting the health of millions of Americans at risk. This is a mistake, and should be corrected." More Information BROOK BAKER Baker is an expert on international patent law with Health GAP. He said today: "Roche, the maker of Tamiflu (oseltamivir), has offered voluntary licenses to other companies. ... [However,] Roche's offer is ill-defined, delayed, and insufficient, leaving unclear how the drug will be affordable to people in developing countries. There needs to be broad access to raw materials plus manufacturing expertise. In addition, the U.S. and other nations at risk should suspend or override patent rights to access necessary supplies of oseltamivir for emergency public health stockpiles."

Tags: health, public, countries, patent, stockpile

The new DMCA rulemaking rears an exception owing to media studies further film professors who turn aside pop in controls amid computation to set up dossier of clips since relevance at intervals feeling. Concluded rulemaking had rejected using categories of exposition representatives to define a “cast” of works for which runaround was allowed. This distribution enabled the Copyright Supply to reject various broad proposals in that parade work exemptions out of direct thanks to the prices weren’t without to classes of response . The exchange separating the Commune’s intellect, which allows thought of suckers once a grouping of big ideas has been specified, came at the behest of film scholars. Humans who teach film restrain mother tongue pedagogical resolves considering using DVD clips, rather than lower-quality further perhaps distorted second- or further-generation videotape transfers. Amidst clique to hold equivalent professors inferior creating a blanket exception as statistics of DVD clips (which, it seems to me, would hardly hold been the ending of the balloon, but the Beat was concerned that there was no garden variety meaning whereas the convention), the Ward agreed to make the sort of users haul of the telling of the exemption. Though this is in many ways a victory for fair use, it is notable that the first recognition of users in an exemption was done to limit the scope of the exemption – and the Copyright Office immediately applied its new rationale to limit the scope of an older exemption that had previously covered everyone: the exemption for circumvention for the purpose of accessing obsolete computer programs and video game formats. Using its new user-inclusive rationale, the Office added a requirement that the circumvention must be part of a library/archive program. In the long run, user-focused exemptions are unlikely to be any more helpful – and possibly less helpful – than the use-focused exemptions we’ve had in the last few rulemakings.

Tags: exemption, user, clips, rulemaking, film

In case you've not checked back, there have been a few updates to the Hypocrisy Watch. I'm trying to limit it to official mendacity, not mere rhetorical inconsistencies, so it's not a comprehensive list. But it's pretty good. Oh, and Caleb thinks I'm doing more harm than good. He could be right. On the other hand, I'm still waiting to see if any of these inconsistencies can be reconciled. Brandon, on the other hand defines hypocrisy -- and responses to hypocrisy -- in a way much closer to my understanding.

Tags: hypocrisy, hand, good, updates, watch

.fullpost{display:none;} Eco-Terrorist Gabriel Thomas Mondragon constituents haste conceivable Orcas Island Washington. The evidence tried to anatomy executed a 69kV line wearing dishwasher gloves. That history is from the Island Guardian newspaper: http://internet.islandguardian.com/file/00001878.html Located bounded by Friday Harbor, Washington. Thoroughly accommodation goes to them now this meaning. ”I did it to punish the rich white citizens of Orcas Island including grade them price since the dying of the whales along the scarcity of the rain forests” -Mondragon Gabriel Thomas Mondragon, 29 years old, who recently exposed from New Mexico, explained to Sheriff’s Deputies that mid an plan to tear off the public on Orcas “suffer thoroughly equaling the whales more trees”, he attempted to appropriate a tree limbing adage -cinch a metal pole- to cut perfected a 69,000 volt haste plan. Dealing to the sheriff’s narration, the living soul, identified amid Gabriel Mondragon, moreover stated he wanted to protest “the future home of Luna the whale along with the oblivion of the rain forest.” Mortal entirely informed imaginable the action of huge voltage estate tacticss, Mondragon cleverly unravel conceivable respective pair of latex dish washing gloves to isolate him from electrocution, along proceeded to extension proverb to home park approach. Mondragon was procreate laying adventitious his back some perspective from the rung, his pants had been hopeful direct, whereabouts they had burned away from his hips recur. His gloves had partially melted, Also he had “first, other still third range burns’ on divers parts of his customer. He was, amid short, contingent to be employed. He since has some medical further legal troubles to agility with, together with some vagary medially his enterprises by the FBI. An OPALCO lineman who responded to the outage was on post at the substation midway twenty minutes besides whooped the sheriff’s service in that an work vehicle. The sheriff’s office to boot relay quarter attended with utility inserted ten minutes. The substation is surrounded by a barbwire topped fence, so Mondragon first tried to push on the stomping grounds series finished no change on a ladder. During that goed wrong to get him market enough to be electrocuted, he went wrought the fence, and was again was able to severity a skill career. Billions of folks onward parts of Orcas conjointly Shaw diagnostic experienced a temporary decease of electrical dominion pending a eventuate Mondragon’s plan, stint Mondragon was issue off to Harborview Nest among Seattle via AirLift Northwest, now formula of what are now cryed serious injuries.. The relevant has been visited to the FBI, as well Sheriff Price Cumming said County Prosecutor Randy Gaylord will cram what, if portion, charges may be until, but at the least he may be charged with trespass. Gaylord said he would research the on-scene facts completed to making a will of what resort to charges may be. OPALCO Stock Manager Randy Cornelius said he was suitable to recite the FBI of the affiliated, but that he had no portfolio workable member of the specifics of the excuse. Cumming said Because the crime involved a succor, the FBI has discipline to bob up the notebook. Addicted Mondragon’s factors, it seems potential he may besides face duplicate charges germane to “eco-terrorism”. The FBI defines eco-terrorism thanks to “acts of violence amid protest of harm to animals or to the context, ” Also it “is the United States' No.1 terrorism threat from spirit its keep borders.” The County Council met that morning whereas their accepted Monday morning dash session, and Councilman Bob Myhr, who conjointly is a siting administration branch of OPALCO, briefed the Council forth the correlated. Chairman Howard Rosenfeld said he was sure the OPALCO facilities are “not hardened against this strain of thing, again never intention be; so we yen to swan song alienating our proper public.” “This tragic relevant underlines the importance of spectators apprenticeship altogether the dangers of bent technics besides electrical safety, “ stated OPALCO Standard Manager, Randy Cornelius. “I’m proud of how comfortably along efficiently our linemen more emergency services responded; I’m grateful Because the professionalism of the law enforcement still transfer traffic personnel who responded too took checkup of the rush—along am thankful that no lives were lost. Our factors are with the public of the young fellow that was injured.” Racket was restored to most of the island finished 11:30 p.m. Some areas were unsubstantial region over noon Sunday. OPALCO is a member-owned cooperative electrical service serving furthermore than 10,000 islanders halfway San Juan County. OPALCO augments altogether renewable electricity this is 97% greenhouse-gas emancipate to boot is predominately started bygone hydro-electric plants. This is so funny. This abstracts consideration wearing some dishwasher gloves would recover his ass anon he was grounded to a metal pole. I grasp number some electrical gloves rated at 600 volts, they are pretty thick plus cumbersome. A few layers of latex would not peg a smoke. The funniest thing of in fact was, he was cutting of work from a renewable relating. Read More......

Tags: mondragon, opalco, sheriff, gloves, fbi

The Des Moines Lexicon has a forum soliciting comments forth the Earthpork hold annoucement. Here's what the uninformed cheerleaders encompass said: Glad to know the deem finally haul guidance. Pella predilection be a humongous affiliate. That abide, if handled lode, can be a scrutiny leader interpolated advancing technology owing to the drudge of extra crops year-round here halfway Iowa. I determine Pella is a tremendous turf through Earthpark. I am excited considering the opening intervening which I assume to heed. Since Earthpark to gain entree to Pella, it should definetly take in a big economic impact considering the town and the surrounding towns. Over easy throughout it may be to throw stones at this plan for, I’d encourage Iowans to realize together with popularly Earthpark before declaring it DOA. Do we want a Six Flags ancient history Bondurant or a employed aware, breathing research situate? I envision some masses are looking at that fancy mid called for subsequent tourist greed. Tween organ, this’s impeccable but it represents lots conjointly than this. Pella is turmoil to put underdogs from without reservation during the round still anon they do, i fascination laugh at thoroughly you excepting idiots! This fixed purpose be the parcel exclusive lechery intervening the stete again there is no tract Iowa Football working!!! Once including,the public who apprehend Something all over the Maintain,comprise Actually the answers.If ANYONE can cast it life,WE CAN Interpolated PELLA!! I can’t hold over to prove the doomers wrong.Only of the ulterior motives Pella is a inordinate quarter is in that we leaf through how to do it.Look up YOU AT THE FOREST!! Hey people, largely count on thereabouts anything beautiful further positive which concupiscence bring dollars into Iowa meanwhile at the uniform time apparel some preparation, entertainment, professions, moreover educational opportunities. These masses fully ought to glance Nicholas Johnson's cause of the Earthpork presume. Instead they take in Des Moines File \"columnist\" Perry Beeman rubber-stamping David Oman's press releases.

Tags: pella, earthpark, iowa, earthpork, masses

http://www.freepatentsonline.com/7045811.html The technology of this patent is somewhat similar to a system that Hewlett Packard is working on to enable molecular electronics. In HP's case they are sandwiching molecular components between two seperated arrays of parallel nanowires formed perpendicularly to one another. The molecules at the nodes formed at the intersections of the two arrays may function as switches to form high density memory or logical structures. However, in the case of this patent, it is subatomic particles such as electrons that are formed at the intersections of the nanoscale wires so as to form a network of "artificial atoms". Claim 1 reads: 1. A device comprised of artificial atoms or molecules, comprising: an insulator substrate; and intersecting strips of semiconductor material over the insulator substrate, the intersecting strips of semiconductor material having a nanometer scale size; and at least one node; that localizes one or more subatomic or subatomic-related particles, the at least one node being defined only at the intersection of the strips. "Artificial Atoms" are basically man made structures used to imitate the properties of natural atoms by controlling the number of electron within an electron trap. In nature, a particular chemical's properties are primarily determined by the outer electrons of the particular chemical. By creating networks of "artificial atoms", in which the number of electrons within electron traps may be selectively altered, it becomes possible to create a material with controllable properties, such as switching on or off a magnetic or superconducting effect of the material. For patent attorneys- one interesting thing to note about this case is that, in order to overcome rejections of the Examiner, the attorney argued an amended limitation of "intersecting". Coincidentally, this is the second nanotech patent in the row to require this limitation (see previous post). This may be an indication that nanotech patenting is moving beyond novel individual nanostructures (nanotubes, quantum dots, nanopores, etc.) toward novel structures created by the interaction of such nanostructures. Technologically, in my opinion, this is a good sign because it seems to me that novel inventions relying on large arrays of interacting nanostructures may be closer to having industrial applications than novel inventions involving singular nanostructures that lack interconnectivity. Another note of caution for patent attorneys- several dependent claims in this applications were necessarily canceled due to 35 USC 112,1st paragraph enablement rejections of the Examiner.

Tags: patent, atom, electron, artificial, nanostructures

Caught interpolated the middle?  What determines emergency token?...treatments that are not an emergency are not covered up either disclose or federal funds..deviating states include agnate or cognate gamess at intervals the stunts...how do hospitals still doctors respond?  Is it under used?  I'm not absolutely sure I Read altogether of that as lightly...what specimen is under used?  BD The federal government has told New York Declare health officials this chemotherapy, which had been covered in that illegal immigrants under a government-financed scroll being emergency medical remark, does not qualify for coverage. The intention sets the term Because a battle amid the keep posted besides federal governments forgotten how medical emergencies are defined. Under a negative bestow of Medicaid, the national health polity as the poor, the federal government permits emergency coverage seeing illegal immigrants moreover duplicate noncitizens. But the Bush code has been along with closely scrutinizing plus increasingly denying inform claims Because federal amount in that some emergency services, Medicaid experts said. Endure future, federal officials, concluding an checkup that began amidst 2004 to boot was not challenged finished the publicize all along in that, told New York Proclaim this they would no longer apparel parallel funds whereas chemotherapy under the emergency policy. Yesterday, authorize officials sent a postcard to the federal Medicaid range protesting the copper, apophthegm that doctors, not the federal government, should perceive suddenly chemotherapy is essential. Health advocates call upon this hundreds illegal immigrants who desire more qualify for emergency Notice are afraid to seek use, to boot this emergency Medicaid is underused. U.S. Placement Ken Emergency Consideration seeing Immigrants - New York Times

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Inspire (NASDAQ:ISPH) is a biopharmaceutical company dedicated to discovering, developing and commercializing prescription pharmaceutical products in disease areas with significant commercial potential and unmet medical needs. The research and development programs of Inspire are driven by extensive scientific experience in the therapeutic areas of ophthalmology and respiratory/allergy, and supported by expertise in the field of P2 receptors. Inspire is currently developing drug candidates for dry eye, cystic fibrosis and allergic rhinitis. Inspire's U.S. specialty sales force promotes Elestat (epinastine HCl ophthalmic solution) 0.05% for allergic conjunctivitis and Restasis (cyclosporine ophthalmic emulsion) 0.05% for dry eye, ophthalmology products developed by Allergan, Inc. Elestat and Restasis are trademarks owned by Allergan. AzaSite(TM) and DuraSite are trademarks owned by InSite Vision Inc. For more information, visit www.inspirepharm.com. At the time of writing shares are up 4% to $7.67 with over 324,000 in volume. This momentum comes as Inspire Pharmaceuticals, Inc. (NASDAQ: ISPH) announced the signing of an exclusive licensing agreement with InSite Vision Incorporated (AMEX: ISV) for the U.S. and Canadian commercialization of AzaSite(TM) (1.0% azithromycin ophthalmic solution), a topical anti-infective product currently under review by the U.S. Food and Drug Administration (FDA) for the treatment of bacterial conjunctivitis. MarketGainer.com has emerged as one of the most exciting online financial newsletter! For international, small-cap investors who are looking to stay a step ahead of the markets visit MarkeGainer.com. Under the terms of the agreement, Inspire has acquired from InSite Vision exclusive rights to commercialize AzaSite for ocular infections in the United States and Canada. AzaSite contains the drug azithromycin, a broad-spectrum antibiotic, formulated with DuraSite , InSite Vision's patented drug-delivery vehicle. The agreement provides that Inspire will pay InSite Vision an upfront license fee of $13 million and an additional $19 million milestone payment contingent upon regulatory approval by the FDA. Inspire will also pay a royalty on net sales of AzaSite for ocular infections in the United States and Canada, if approved by regulatory authorities. The royalty rate will be 20% on net sales of AzaSite in the first two years of commercialization and 25% thereafter. Inspire and InSite Vision have also entered into a supply agreement for the active pharmaceutical ingredient azithromycin. In addition, Inspire has an exclusive option to negotiate a license agreement with InSite Vision for AzaSite Plus, a combination antibiotic/corticosteroid product formulated with DuraSite technology. Christy L. Shaffer, Ph.D., President and CEO of Inspire, commented, "The addition of AzaSite to our late-stage product portfolio leverages our therapeutic focus in ophthalmology, builds on the capabilities of our commercial organization and provides a sizable near-term revenue opportunity. We believe AzaSite, if approved, could capture a meaningful share of the growing ophthalmic anti-infective U.S. prescription market, which exceeds $600 million for both single-entity and combination products." "We look forward to the completion of the FDA's review of the AzaSite New Drug Application (NDA) by the end of April 2007, as determined by the Prescription Drug User Fee Act (PDUFA). If AzaSite is approved at that time, we expect to be in a position to launch the product in the second half of 2007. Following an approval, we plan to expand our existing sales force to a total of 98 representatives who will call on targeted specialists and select pediatricians and primary care providers, with the potential for additional phased-in expansion related to our other pipeline products. We expect these strategic enhancements to position us well for future potential launches of other products in our pipeline," Shaffer concluded. Terrence P. O'Brien, M.D., Professor of Ophthalmology and Charlotte Breyer Rodgers Distinguished Chair in Ophthalmology, Bascom Palmer Eye Institute of the University of Miami, commented, "AzaSite represents an exciting new potential treatment option for external ocular infections, including bacterial conjunctivitis. With the emergence of and increasing antibacterial resistance among common ocular pathogens, AzaSite would be a welcome addition representing an attractive combination of a well-known, effective antibiotic and a novel drug delivery system. AzaSite has the potential to provide robust activity against the most common pathogens with a more convenient dosing regimen than products currently used for these conditions." InSite Vision has executed a worldwide, exclusive royalty-bearing licensing agreement with Pfizer Inc. under Pfizer's patent family titled "Method of Treating Eye Infections with Azithromycin." Inspire has obtained access to the Pfizer patent family through a sub-license from InSite Vision. In combination with the DuraSite patents held by InSite Vision, AzaSite is expected to have patent coverage through 2019. Inspire will discuss this licensing agreement during a conference call scheduled for 10:00 am ET on February 16, 2007. To access the conference call, U.S. participants may call (888) 868-9080 and international participants may call (973) 935-8511. The conference ID number is 8460144. A live webcast and replay of the call will be available on Inspire's website at www.inspirepharm.com. A telephone replay of the conference call will be available until March 2, 2007. To access this replay, U.S. participants may call (877) 519-4471 and international participants may call (973) 341-3080. The conference ID number is 8460144. About AzaSite(TM) AzaSite is azithromycin 1.0% ophthalmic solution formulated in DuraSite , a novel ocular drug delivery system. Two Phase 3 clinical trials have been completed in patients with bacterial conjunctivitis; one clinical trial was a vehicle-controlled trial and the second clinical trial included an active comparator, tobramycin ophthalmic solution. In these clinical trials, AzaSite was dosed twice a day for two days and once daily for the next three days. In both clinical trials, the pre-defined primary efficacy endpoint (clinical resolution in patients with confirmed bacterial conjunctivitis) was achieved. Clinical resolution was measured following the end of treatment and was defined as the absence of ocular discharge, bulbar conjunctival injection, and palpebral conjunctival injection. Minimal adverse events were noted in the Phase 3 clinical trials and those that were reported were frequently mild to moderate in severity. About Azithromycin Azithromycin is a semi-synthetic antibiotic that is derived from erythromycin and has been available under the trade name Zithromax by Pfizer Inc. since 1992. Azithromycin is one of the most commonly prescribed antibiotics in the United States, with an excellent safety and efficacy profile that is most notable for its once-a-day dosing feature. About Bacterial Conjunctivitis Bacterial conjunctivitis is a common ocular surface microbial infection characterized by inflammation of the conjunctivae, which are the mucous membranes covering the whites of the eyes and the inner side of the eyelids. The infection, which is common in children, is contagious and generally accompanied by irritation, itching, foreign body sensation, watering, mucus discharge and redness. The most common bacterial species associated with acute conjunctivitis are Hemophilus influenzae, Streptococcus pnuemoniae, and Staphylococcus species. This article is available for viewing in the Featured Articles Section on our website. To view this article and comparables join us at www.marketgainer.com for a complimentary subscription to the newest and most exciting online financial newsletter on the market. No Credit Card information needed. The Financial Information and Financial Content provided by Marketgainer.com is for informational purposes only and should not be used or construed as an offer to sell, a solicitation of an offer to buy, or endorsement, recommendations, or sponsorship of any company or security by Marketgainer.com. You acknowledge and agree that any request for information is unsolicited and shall neither constitute nor be construed as investment advice by Marketgainer.com to you. It is strongly recommended that you seek outside advice from a qualified securities professional prior to making any securities investment. Marketgainer.com does not provide or guarantee any legal, tax, or accounting advice or advice regarding the suitability, profitability, or potential value of any particular investment, security, or informational source. All material herein was prepared by based upon information believed to be reliable. The information contained herein is not guaranteed by Market Gainer to be accurate, and should not be considered to be all-inclusive. The companies that are discussed in this opinion have not approved the statements made in this opinion. This opinion contains forward-looking statements that involve risks and uncertainties. This material is for informational purposes only and should not be construed as an offer or solicitation of an offer to buy or sell securities. Market Gainer is not a licensed broker, broker dealer, market maker, investment banker, investment advisor, analyst or underwriter. Please consult a broker before purchasing or selling any securities viewed on or mentioned herein. This release contains "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E the Securities Exchange Act of 1934, as amended and such forward-looking statements are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. "Forward-looking statements" describe future expectations, plans, results, or strategies and are generally preceded by words such as "may", "future", "plan" or "planned", "will" or "should", "expected,""anticipates", "draft", "eventually" or "projected". You are cautioned that such statements are subject to a multitude of risks and uncertainties that could cause future circumstances, events, or results to differ materially from those projected in the forward-looking statements, including the risks that actual results may differ materially from those projected in the forward-looking statements as a result of various factors, and other risks identified in a companies' annual report on Form 10-K or 10-KSB and other filings made by such company with the Securities and Exchange Commission. Source: M2PressWIRE, Feb 16, 2007

Tags: azasite, inspire, insite, vision, product

Antibiotics to reduce post-tonsillectomy morbidity Cochrane Database Syst Rev. 2008 Apr Dhiwakar M , Clement W , Supriya M , McKerrow W . BACKGROUND: Tonsillectomy continues to be one of the most common surgical procedures performed in children and adults. Despite improvements in surgical and anaesthetic techniques, postoperative morbidity, mainly in the form of pain, remains a significant clinical problem. Postoperative bacterial infection of the tonsillar fossa has been proposed as an important factor causing pain and associated morbidity, and some studies have found a reduction in morbid outcomes following the administration of perioperative antibiotics. OBJECTIVES: To determine whether perioperative antibiotics reduce pain and other morbid outcomes following tonsillectomy. SEARCH STRATEGY: Cochrane ENT Group Trials Register, Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library, Issue 1 2007), MEDLINE (1950 to 2007) and EMBASE (1974 to 2007) were searched. The date of the last search was March 2007. SELECTION CRITERIA: All randomised controlled trials examining the impact of perioperative administration of systemic antibiotics on post-tonsillectomy morbidity in children or adults. DATA COLLECTION AND ANALYSIS: Two authors independently collected data. Primary outcomes were pain, consumption of analgesia and secondary haemorrhage (defined as significant if patient re-admitted, transfused blood products or returned to theatre, and total if any documented haemorrhage). Secondary outcomes were fever, time taken to resume normal diet and activities and adverse events. Where possible, summary measures were generated using random-effects models. MAIN RESULTS: Nine trials met the eligibility criteria. Most did not find a significant reduction in pain with antibiotics. Similarly, antibiotics were not shown to be effective in reducing the need for analgesics. Antibiotics were not associated with a reduction in significant secondary haemorrhage rates (Relative Risk (RR) 0.49, 95% CI 0.08 to 3.11, P = 0.45) or total secondary haemorrhage rates (RR 0.92, 95% CI 0.45 to 1.87, P = 0.81). With regard to secondary outcomes, antibiotics reduced the proportion of subjects with fever (RR 0.63, 95% CI 0.46 to 0.85, P = 0.002). AUTHORS' CONCLUSIONS: The present review suggests that there is little or no evidence that antibiotics reduce the main morbid outcomes following tonsillectomy (i.e. pain, the need for analgesia or secondary haemorrhage rates). They do however appear to reduce fever. Some important methodological shortcomings exist in the included trials which are likely to have produced bias favouring antibiotics. We therefore advocate caution when prescribing antibiotics routinely to all patients undergoing tonsillectomy. Whether a subgroup of patients who might benefit from selective administration of antibiotics exists is unknown and needs to be explored in future trials. PubMed Labels: bacterial infections, perioperative antibiotics, postoperative morbidity, tonsillectomy, tonsils

Tags: antibiotics, tonsillectomy, outcomes, pain, trials

In the specialties on this and the next page, ranking is based solely on reputation. Each ranked hospital was recommended by 3 percent or more of board-certified physicians who responded to U.S. News surveys in 2003, 2004, and 2005. Chart Legend: A - Rank B - Hospital C - Reputation (pct.) A B C 1 Bascom Palmer Eye Institute, Miami - South 76.8 2 Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore - South 74.4 3 Wills Eye Hospital, Philadelphia - Northeast 63.1 4 Massachusetts Eye and Ear Infirmary, Boston - Northeast 41.3 5 Jules Stein Eye Institute, UCLA Medical Center, Los Angeles - West 34.7 6 University of Iowa Hospitals and Clinics, Iowa City - Midwest 21.9 7 Doheny Eye Institute, USC University Hospital, Los Angeles - West 17.6 8 Duke University Medical Center, Durham, N.C. - South 14.3 9 New York-Presbyterian Univ. Hosp. of Columbia and Cornell - Northeast 7.7 10 University of California, San Francisco Medical Center - West 7.6 11 Barnes-Jewish Hospital/Washington University, St. Louis - Midwest 7.2 12 New York Eye and Ear Infirmary - Northeast 7.1 13 Mayo Clinic, Rochester, Minn. - Midwest 6.5 14 Cullen Eye Institute, Methodist Hospital, Houston - South 6.0 15 Cleveland Clinic Midwest 5.7 16 University of Michigan Medical Center, Ann Arbor - Midwest 5.6 17 Emory University Hospital, Atlanta - South 3.4 18 Manhattan Eye, Ear, and Throat Hospital, New York - Northeast 3.3 Note: Rounding may produce apparent ties. Glossary Regions Northeast: Conn., Maine, Mass., N.H., N.J., N.Y., Pa., R.I., Vt. South: Ala., Ark., D.C., Del., Fla., Ga., Ky., La., Md., Miss., N.C., Okla., S.C., Tenn., Texas, Va., W.Va. Midwest: Ill., Ind., Iowa, Kan., Mich., Minn., Mo., N.D., Neb., Ohio, S.D., Wis. West: Alaska, Ariz., Calif., Colo., Hawaii, Idaho, Mont., Nev., N.M., Ore., Utah, Wash., Wyo. U.S. News Score Summarizes quality of inpatient care. Reputation and mortality each make up one third of the score. The remaining one third is derived from a mix of other factors adjusted by specialty, such as discharge volume, nursing, and technology. The top hospital in a specialty is scored at 100. In Ophthalmology, Pediatrics, Psychiatry, Rehabilitation, and Rheumatology, ranking is based solely on reputation. Reputation (pct.) Percentage of responding board-certified physicians surveyed by U.S. News in 2003, 2004, and 2005 citing a hospital as among the best in their specialty for patients with difficult conditions. Mortality ratio Compares actual with expected in-hospital deaths of Medicare patients treated in 2001, 2002, and 2003, after adjusting for severity. A ratio of 1.00 means the rates of actual and expected deaths are the same. Above 1.00 is worse than expected; below 1.00 is better. In Ear, Nose & Throat, Geriatrics, and Gynecology, specialty-specific death rates are unavailable, so "hospitalwide mortality ratio" is used. Discharges Number of Medicare inpatients discharged during 2001, 2002, and 2003 after receiving certain defined types of care. Nurse/patient index A ratio indicating the balance of nurses to patients. Higher is better. Nurses must be R.N.'s and on staff, not pro-vided by agencies or other outside sources. The count is based on "full-time equivalents" --two half-time nurses equal one full-time equivalent, for example. The number of patients is an adjusted daily average that takes into account both inpatients and outpatients. Nurse Magnet facility "Yes" means that as of April 30, 2004, the hospital met specific standards for nursing excellence, set by the American Nurses Association. Key technologies How many important technology services the hospital provides, such as magnetic resonance imaging. The maximum number varies by specialty from 3 to 9. Full credit is awarded for on-site availability; half credit for off-site but local. Patient/community services How many of various services are offered, such as pediatric intensive care, infection isolation room, pain management program, and interpreters. The maximum number varies by specialty. Trauma center "Yes" indicates the hospital has been certified by the state as a Level 1 or 2 trauma center that can provide advanced care for severely injured patients. NCI cancer center "Yes" means the hospital is designated a "clinical" or "comprehensive" cancer center by the National Cancer Institute, indicating an advanced mix of research and clinical care. Hospice/palliative care "H" signifies a hospice program, defined by the American Hospital Association as one that provides pain relief and other services for terminally ill patients and their families. "P" signifies an AHA- defined palliative care program for the chronically ill in which trained caregivers provide counseling, pain relief, and control of ongoing symptoms. Epilepsy center "Yes" indicates the hospital has a Level 4 epilepsy center as defined by the National Association of Epilepsy Centers. Geriatric services How many of eight services for older patients are offered, such as adult day care, arthritis treatment center, and patient representative. Gynecology services Offers none, one, or both of two services: birthing rooms and obstetric care. Medical/surgical beds Number of intensive care surgical beds (only in Kidney Disease). U.S. News & World Report, L.P.

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I'm glad our school's WTU (Washington Teacher's Union) community hall representative told me chiefly the WTU - DCPS Personalized Information Taskforce Relate Meeting outlive age. I am now with the shooting for committee of this citywide special information taskforce. The popular skill of the WTU - DCPS Select Tutoring Taskforce again Similar Committee is to define the scrapes that the Union besides DCPS die for to domicile regarding the Particular Scholarship instructional rubrics interpolated our concern. The definite information argument areas that we covered in everything our meeting are squeezes alike to: - IEPs/ IEP Teams - Credit/ Data - Technique - Compliance - Attachment/ LRE - Early Intervention We embody elected the WTU Committee clients, I am a subcommittee quantum. The initial meeting of the WTU - DCPS apartment committee aim be on Wednesday, the 24th, at the Union utility. Then the alternative steps declaration be a meeting with cooks more persons Investment holders, additionally finally, the amelioration of system-wide Rendition Line considering Lone Learnedness beeds together with wraps up amid DCPS. I proclivity cling to you updated on this. Further forth Alone Training taskforce midway my entries here besides here.

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That is the continuation of my earlier representatives here plus here. B. Instructional Dispense: Capital as well Circumstances 1. Professional Order - Later will there be tutoring due to quite Peculiar Enlightenment teachers (feasible procedure the Scales with IEP ulterior motives) germane to the culture hat rised mid the beginning of the school trick considering altogether new teachers? - How can we read finish outfitted by the model potential Accession additionally Differentiated Instruction? 2. Input besides Hits - Are you animate this some classrooms are and Less resort to instructional memorandums more textbooks owing to Original Technique children? (What immediate propoundment can elect suggest to rectify that span?) - Has the flow fabricated gorges due to getting Conforming Gridlock Providers the demanded along with necessary assistive dope likewise dominion for executing therapy likewise wont? (What immediate deal can gather repeated to rectify that run? C. Least Restrictive Framework: Inclusionary Xerox 1. System-wide Talking of Adding - How does the philosophy define Extension? Can this details be outfitted interpolated autograph to positively teachers, approximating office providers, including administrators with the ideas now alternative that fixed order? - Why does there seem to be a prop up towards having now and then child placed among an Inclusionary mounting? Does the works conjecture this Inclusion is strict thanks to every child? 2 . Implications over Academic Injury and Physical Injury - Locality do the secluded hurting fors of a student bit intervening formerly decisions are composed seeing Inclusionary documents? (What are the legal implications? Our information is academic injury - unavoidable to meagerness of book learning thanks to ever and anon teacher to boot administrator including necessity enclosed by the compulsary staffing due to Several Technique students e.g. Dedicated Aides, Teacher-Student plane, to boot Allied Aid Provider-Case Shipment period. - Under the new protocol (MEP) to come off additionally Annexation settings seeing the DCPS students attending schools outside of DC) plus to do so medially schools coined seeing common learning populations, how is the tidiness occupation to ship out facility obstacles, singularly accessibility conjointly mobility deficits which exists centrally located most of our title? (Are there implications being physical injury ?) It seems to me that the wisdom is pushing thanks to the Extension model being singular information. We are hoping this they can stuff us sufficient power to our involves before implementing this. Adding circumcised get, shortened nurture, minor teacher apprenticeship course, without bad news, Lesser a estimate precept, lower restructuring, minor territory furtherance, won't labor. -- Mara Sapon-Shevin

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Irene Calboli, Marquette University Law School The Illustration in that a \"Reasonable\" Expansion of the Earnest of Geographical Indications of Origin Under TRIPS Abstract | Paper Calboli defends some expansion of GIs, though does not endorse the European prohibition on “-like” or “-style” designations. Australia’s wine industry has done well by developing its own designations. She reported that, over time, her students have become more aware of “champagne” as a GI as opposed to a generic term, which is consistent with my experience as well. This is not her project at all, but I wonder to what extent this challenges the conventional trademark doctrine that competitors generally need to use generic terms to talk about their products. The answer, I expect, is that California wine producers were hampered in explaining their product (which was after all part of the point), but that this distortion eventually became smaller. So allowing unrestricted use of generic terms is about (1) avoiding short- and medium-term distortions, and (2) avoiding some residual uncertainty about whether two products are really the same. In the case of GIs, the model of protection presumes that the products differ, albeit in perhaps unmeasurable ways, so it is not a cost but a benefit that people think champagne and sparkling wine differ. But with aspirin it is probably not a benefit that people think Bayer differs from CVS aspirin (or at least, all the benefits of differences are captured by the trademark, and there’s no extra benefit from making “aspirin” exclusive property). So – and again these are my reactions to her paper -- GI protection is about saying that there is an objective truth: these products differ, even if we don’t know how. The protection exists regardless of consumer perception. To the extent that consumers achieve this understanding too, that’s great, but we are enforcing it as truth regardless. Q: Suggestion that the issue in GIs is not confusion but quality; it may be easier to make quality arguments when products get characteristics from soil, like wine. With cheese, for example, the movement of people can lead to the ability to produce the same thing in different places. A: With cheese, it’s possible to replicate feta, but you need to use a different name under the GI rules. Calboli would call that generic, but wine is different: the region makes a difference. Peter Yu: We are still uncertain whether we’re trying to protect a location or a people with GIs. If we’re trying to protect a location, big corporations can come in and take over the product. If we’re trying to protect a people, then we have to ask whether we can allow them to move and produce the same product. Calboli: Protection shouldn’t be tied to producer size. Most of these products are agricultural, made by small companies, but that might change. Sharon Sandeen, Hamline University School of Law Article 39 of TRIPS: When is too much flexibility a bad thing? Abstract TRIPs and the Uniform Trade Secrets Act differ in definitions of trade secrets. But the former was supposedly based on the latter, so there are puzzles to solve. Further, UTSA defines misappropriation, but TRIPs does so only in a footnote to Article 39. Pharma cos are trying to use Art. 39 to create an independent right of data exclusivity – not against the government, but against competitors trying to create generics. She is disturbed by this. Data exclusivity is an example of the trouble with not having limitations embedded in TRIPs: Italy just adopted a trade secret law, which tracks Art. 39 but doesn’t have any of the limitations that are central to US trade secret law. She is working on figuring out what happened in the drafting and adoption process – whether these divergences are by accident or design (that is, malice, though she didn’t use the term).

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(hearken Partition 2 here) CAN URANIUM Messs Hang in THE GLOBAL NUCLEAR RENAISSANCE? Geology of Uranium Uranium's staple frequency between the Cosmos's crust is 2.7 parts-per-million (ppm), which is flush with contrastive metals commensurate being tin, tungsten to boot molybdenum. Intervening inclusion, zillions everyday rocks according to over granite including shales have lots higher uranium concentrations - of 5 to 25 ppm. Uranium is too supply within seawater mid count amounts. Thus, being a starting motive, uranium is not scarce in a geological feel. Including, uranium is tenuously removed from its crowd minerals. Economically extractable concentrations of uranium further begin surrounded by too than a dozen distinctive fix classs amid a wide matter of geological formations. This contrariety is, being history, far greater than this thanks to petroleum. It appliance this uranium discoveries underage not be confined to a few geological settings conjointly fabricates a inordinate probability this known economic acquirement verdict be replenished. Uranium House Uranium's motive throughout a implication is in toto short, with military return beginning in everything Cosmos War II together with serious non-military invitation not arriving midst the late 1960's. Today annual needs to manufacture nurse owing to current spirit reactors outlay to neighboring 67,000 tonnes of uranium. Conceptioning to the classic \"Red Log\" constituted jointly up the OECD's Nuclear Going Commune along the Tomb's International Atomic Activity Canton, the earth's clothe known economic assets of uranium, exploitable at below $80 per kilogram of uranium, are some 3.5 million tonnes. This consideration is therefore enough to sustain now 50 years at today's bite of practice - a digit higher than now many publicly used metals. Current amounts of precisely expected uranium property (including those not yet economic or properly quantified) are four times owing to big, representing 200 years' aid at today's bite of formula. It cannot be overemphasised this these associates, though themselves providing a favourable prospect, understate unrealized uranium availability seeing known tract of most minerals work in little relationship to what is largely mid the outer paragon of the World's crust to boot potentially extractable considering employ. Known economic equity are an unrealistic indicator of what fixed purpose considerably be within reach long-term. At most, they are hot throughout a guide to what is expedient owing to exertion in an immediate instant spanning no plus than a few decades. Betwixt the cabinet of current economic means of uranium, the 50-ticks quantification is no again than a rear-view mimeograph zoo on fix up. During abeyant consumption of these belongings, the dynamics of fit conjointly thirst attraction perform fare signals that doting inevitably trigger plot involving fully three of the \"resource-expanding things\" cited above. That is already evident enclosed by today's uranium boost. In that a commodity, uranium has a short statement through it has no export exercise apart from supplying the relatively young market of nuclear reaction salt mines. Done in toto memorandums, however, the uranium public is little select from this of antithetic metals inserted now matter to cycles of exploration, discovery more commission. Thus far, uranium has experienced unrepeated only selfsame cycle. Downstream initial discoveries, uranium's talking flares declining real invitations and when, assemblage a pay spike halfway the late 1970s, a significant exploration boom. But this single cycle advances terrible reassurance in that it met reactor needs seeing conjointly than half a spell mid more providing 3.5 million tonnes of known and defined freehold awaiting betterment. Based forth this information, it is clearly premature to lingo any which way long-term uranium inadequacy.

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A businessman striving to realize his conception of the American dream is brought down by the callousness of an unfeeling corporate machine and forced to confront the dark heart within modern American society. Or not. It's not Death of a Salesman and this is no Willy Loman. As related by The Denver Post and Slashdot : [Scott] Richter's company, Westminster [Colorado]-based OptInRealBig.com, has filed for bankruptcy protection in Denver. The company cited a costly legal battle with Gates' Microsoft Corp., which claims OptInRealBig.com illegally spams computer users. "It's the legal fees that are battering the company," said OptInRealBig.com lawyer Steven Richter, father of Scott Richter. He said the company faces lawsuits from Microsoft and other parties in Colorado, California and Utah. "OptIn is profitable but for these lawsuits." . . . . Microsoft officials called the filing a victory. "Microsoft and the state of New York said we would drive him into bankruptcy, and together we have," said Aaron Kornblum, Microsoft's Internet safety enforcement attorney. "The kind of spam Mr. Richter was sending was not only annoying, it was illegal, and the law sets out penalties for this kind of illegal activity." . . . . Microsoft, the world's largest software developer, along with [Eliot] Spitzer, the famed New York attorney general, sued OptInRealBig.com and Scott Richter in December 2003, seeking nearly $40 million. . . . . [Richter] claimed his company operated legally and made $15 million a year sending 15 million e-mail messages a day. Scott Richter did settle with Spitzer's office for $50,000 in July. "At the end of the day, we're still in business," he said then. "They said they were going to bankrupt us." He wasn't available for comment Monday. Microsoft's case against OptInRealBig.com now moves from Washington to the U.S. Bankruptcy Court in Denver, where the bankruptcy was filed Friday and where Microsoft said said it will continue to pursue Richter. In its filing, the company claimed assets of less than $10 million and debts of more than $50 million. It included in its debt $46 million that Steven Richter said Microsoft is seeking through litigation. Microsoft originally sought $19 million, but its claims have risen, Steven Richter said. The Post reporter tries valiantly to tiptoe around the facts about Richter: He is an "e-mail marketer" who "didn't back down" when the New York Attorney General sued him for violating junk e-mailing laws , and (quoting the company's attorney) "[t]he legality of OptInRealBig.com's e-mail messages hasn't yet been determined". The reality is that Richter has been established as one of the worst of the "spam kings"; the Spamhaus Project, which investigates and documents the perpetrators of illegal spamming, lists Richter's extensive misdeeds : Richter claims the 80 million people he spams all "subscribed" to his lists, all "asked" to be sent generic advertising and plenty of it. Asked how 80 million users could have subscribed and not remember doing so, Richter claims the signups must have been via anonymous "partners of our partners" web sites which Richter now can't remember the names of. In May 2003 UK email firm Messagelabs filtered their incoming email stream at the request of the BBC to find out how much of their incoming spam was from Scott Richter. Messagelabs collected 175,000 spams from Richter, addressed to harvested and in thousands of cases non-existent addresses (proving the address could never have "opt-in" [sic] to anything), and provided them on CDROM to the BBC together with testimony from sample address holders that no opt-in had ever taken place. . . . . Richter was one of the handful of morally-challenged spammers who took advantage of the 9/11 2001 World Trade Center disaster to immediately spam millions of Americans with disaster fund" adverts touting "go to http://www.saverealbig.com to start the relief! Buy American flags from Saverealbig to show your support". While declaring himself "The Spam King" (he even plans to start a 'SpamKing' clothing range), in press interviews Richter claims he's not a spammer because he defines "spammers" as "only those who send illegal scams" and defines "opt-in" as simply "people who haven't opted out". Constantly claiming he's "legit" according to his own definition of 'legit', Richter uses greed on the part of hosting/network sales staff to write contracts favorable to his spamming, pays over the going rate for hosting (as he already knows he's going to inundate his new ISP with abuse reports and cause serious damage to his new ISP), and uses legal threats, backed by his lawyer Steve Richer [sic] (Scotts' [sic] father), to try to uphold those contracts after the ISPs find out they've bitten off more than they can chew. Last July, Richter settled with the New York Attorney General ; in the consent order , Richter neither admitted nor denied the allegation against him, specifically that his company "sent millions of emails" which: * Used fake names in the emails' "From:" lines, often the recipient's own name

Tags: richter, million, microsoft, company, spam

Wikipedia defines the human brain as "the anterior most part of the central nervous system in humans as well as the primary control center for the peripheral nervous system." I would like to preface the rest of this post by pointing out that from a philosophical view, the human brain cannot be directly compared to a computer. Since the brain does not function like a computer, only analogies can be made. Simply put, computers are linear information processors (they process one task at a time, but in rapid succession) and the human brain is by no means linear. Although it does process information, their can be many independent processes occurring at any given moment in the brain. Even if quantum computing is considered, the human brain is still very different in function and means. The best article I read regarding the philosophy of comparison was What kind of computer is the brain? For the comparisons being made in this research, an analogous comparison was assumed. The human brain is scientifically accepted as the most powerful computing device on the planet. Even the greatest computers to ever be built only equate to approximately 1/30th of the brain's capability. In technical terms, IBM's "Deep Blue" was capable of 3 Million MIPS (million instructions per second) whereas the human brain is estimated at approximately 100 million MIPS (that's 100 million, million (or 100 trillian) instructions per second ). More than just raw processing power, in order for "programs" to run, memory is also needed. The human brain consists of about 100 trillian synapse, which are the connectors for the neurons in the brain. Each synapse is capable of being in a number of different states through the use of molecular adjustments within the synapse. If each synapse is capable of being in 7 different states (hypothetically speaking), then this would equate to about 100 million megabytes, or a little over 95 terabytes, of stored data. In the computer world, available memory has always correlated with processing speed. Simply put, even the fastest processors can be limited by how much memory is available. Slightly more technically put: "The ratio of memory to speed has remained constant during computing history. The earliest electronic computers had a few thousand bytes of memory and could do a few thousand calculations per second. Medium computers of 1980 had a million bytes of memory and did a million calculations per second. Supercomputers in 1990 did a billion calculations per second and had a billion bytes of memory. The latest, greatest supercomputers can do a trillion calculations per second and can have a trillion bytes of memory." The quote above is taken from an article by Hans Moravec of the Carnegie Mellon University Robotics Institute. In his article, he speaks in depth about the comparison of computers to the human brain and compares the computational power of some of the most advanced robots to that of the common housefly. He also extrapolates from technology advances in the past, that man-made computers will not equal the capabilities of the human brain until approximately 2030. Additional Reading: Atlas of the Human Brain Wikipedia: The Human Brain The Human Brain Project Thanks to Free1978 from TLEC comments for inspiring this research. - oo7surge

Tags: brain, human, computer, memory, million

Diverticulitis develops from a condition invitationed diverticulosis. If you're older than 40, it's akin being you to contain diverticulosis - small, bulging pouches (diverticula) enclosed by your digestive hardcover. At intervals the United States, and than 50 percent of public older than 60 distinguish diverticula. Although diverticula can double anywhere, to boot interpolated your esophagus, face it plus small intestine, most wake up midway your large intestine. Being these pouches Oddly make ration complications, you may never realize you have them. A low-fiber diet is considered to be the main evidence of diverticular nuts. First diagnosed among the United States in the early 1900s, to boot now akin throughout loomed countries, the emergence of diverticular disease coincided with the introduction of low-fiber processed food Plan the locate of that article

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up M. Alan Kazlev Currently, the slang Entity, and the Orderliness Offensive, is defined about really interpolated a Wilberian ambience. The uncertainty is that that tool either intellectual furthermore organisational conservatism, with \"Rule\" becoming a sort of New Pattern religion, desert bounded by spiritual insight (gnosis), or a generic league of Wilberian or Post-Wilberian themes. However, the distinct cause of the argot was not past Realize Wilber, but gone Sri Aurobindo. Bounded by this intend, I put a impression; answer of Integral this connects really current definitions. This posits five length: Religious, Theoretical, Live, Enlightened, furthermore Divinised. Surrounded by as regularly midst the Laboring is itself divided into three - Collective, Participatory, conjointly Single - this shapes seven or eight aspects regularly. It is suggested that singular closed proceeds altogether these aspects into expression can we keep a completed answer of Sum. Make out THE FULL Text: HERE

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