News: Carvedilol capsules [Coreg CR (R)]
Posted on April 09, 2008 in Diabetes erectile dysfunction
Over I keep possession been duplicate completed imaginable Carvedilol Coreg® altogether these days, I composition I might seeing well now update readers onward what is trip at the Coreg CR ® front as well. Coreg tablets [now generic] use Carvedilol base. The CR version uses a phosphate salt of Carvedilol. The patent application for the salt was under prosecution {US2005240027}. This has now been granted {US7268156}. The granted main/ first claim reads as under: “1. A compound which is crystalline carvedilol dihydrogen phosphate hemihydrate.” Read the patent, in its entirety, here. The patent has a priority of June 27, 2002 with a US filing of June 27, 2003 and hence should have a normal expiry of June 27, 2023 . The patent is not yet listed in the Orange Book, but I suspect, the listing will happen in a few days time. As regards the formulation, it is a c ontrolled r elease capsule. Glaxo licensed its technology/ patents from Flamel, who also manufactures the product. There are multiple generic approvals/ market players for Carvedilol base tablet, and I suspect, most of them would also be contemplating a generic version of the CR capsule.
Tags: carvedilol, patent, cr, coreg, capsule